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Psychiatry56 papers

Identity disorder

Last edited: 4/15/2026

Overview

Dissociative Identity Disorder (DID) is characterized by the presence of two or more distinct personality states or identities within a single individual, often associated with a history of trauma 13.

Diagnosis

  • Key Criteria: Presence of two or more distinct identity states, gaps in recall of everyday events, personal information, and traumatic events 3.
  • Recommended Tests: Neuroimaging studies focusing on hippocampal and amygdala volumes may provide supportive evidence but are not definitive diagnostic tools 1.
  • Diagnostic Challenges: Reliability of diagnosis remains contentious; no definitive proof links DID solely to childhood trauma, and diagnosis in children is rarely reported 3.
  • Management

  • First-Line Treatments: Psychotherapy, particularly trauma-focused therapies such as Cognitive Behavioral Therapy (CBT) and Eye Movement Desensitization and Reprocessing (EMDR) 3.
  • Adjunctive Treatments: Pharmacotherapy may be considered for comorbid conditions like PTSD; specific drug classes include SSRIs and SNRIs, though exact dosing is not specified in the abstracts 1.
  • Special Populations

  • Pediatrics: DID diagnosis in children is almost never reported, suggesting limited applicability of the diagnosis in this population 3.
  • Comorbidities: DID often co-occurs with PTSD, influencing treatment approaches to address both conditions simultaneously 1.
  • Key Recommendations

  • Prioritize Psychotherapeutic Interventions: Focus on trauma-focused psychotherapies for DID management (Evidence: Moderate 3).
  • Consider Neuroimaging for Research Purposes: Use neuroimaging studies to explore structural brain differences, particularly in hippocampal and amygdala volumes, though not for diagnostic purposes (Evidence: Weak 1).
  • Exercise Caution in Pediatric Diagnoses: Avoid diagnosing DID in children due to lack of reported cases and potential iatrogenic effects (Evidence: Expert opinion 3).
  • References

    1 Blihar D, Crisafio A, Delgado E, Buryak M, Gonzalez M, Waechter R. A Meta-Analysis of Hippocampal and Amygdala Volumes in Patients Diagnosed With Dissociative Identity Disorder. Journal of trauma & dissociation : the official journal of the International Society for the Study of Dissociation (ISSD) 2021. link 2 Grouin C, Rosier A, Dameron O, Zweigenbaum P. Testing tactics to localize de-identification. Studies in health technology and informatics 2009. link 3 Piper A, Merskey H. The persistence of folly: a critical examination of dissociative identity disorder. Part I. The excesses of an improbable concept. Canadian journal of psychiatry. Revue canadienne de psychiatrie 2004. link

    Original source

    1. [1]
      A Meta-Analysis of Hippocampal and Amygdala Volumes in Patients Diagnosed With Dissociative Identity Disorder.Blihar D, Crisafio A, Delgado E, Buryak M, Gonzalez M, Waechter R Journal of trauma & dissociation : the official journal of the International Society for the Study of Dissociation (ISSD) (2021)
    2. [2]
      Testing tactics to localize de-identification.Grouin C, Rosier A, Dameron O, Zweigenbaum P Studies in health technology and informatics (2009)
    3. [3]
      The persistence of folly: a critical examination of dissociative identity disorder. Part I. The excesses of an improbable concept.Piper A, Merskey H Canadian journal of psychiatry. Revue canadienne de psychiatrie (2004)

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