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Benign chondroid syringoma

Last edited: 4/14/2026

Overview

Benign chondroid syringoma is a rare, benign adnexal tumor typically found in the head and neck region, characterized by its chondroid and syringoid histological features 1.

Diagnosis

  • Clinical Presentation: Usually asymptomatic, often discovered incidentally 1.
  • Imaging: Ultrasound and MRI can help delineate the lesion's characteristics and location 15.
  • Histopathology: Definitive diagnosis requires histopathological examination showing chondroid matrix and ductal structures 1.

    • Management

  • Surgical Excision: Recommended for definitive treatment and to rule out malignancy 1.
  • Recurrent Cases: May require further surgical intervention or observation depending on recurrence characteristics 1.

    • Special Populations

  • No Specific Guidelines: Limited data on management in pregnancy, pediatrics, or elderly populations 1.

    • Key Recommendations

  • Definitive diagnosis relies on histopathological examination (Evidence: Expert opinion 1).
  • Surgical excision is the primary treatment approach for benign chondroid syringoma (Evidence: Expert opinion 1).
  • Imaging modalities like MRI and ultrasound support diagnostic evaluation but are not definitive (Evidence: Expert opinion 15).

    • References

    1 Giovagnoni A, De Filippo M, Barile A. Diagnostic and interventional radiology: an update. Acta bio-medica : Atenei Parmensis 2020. link 2 Di Leo G, Sardanelli F. Statistical significance: p value, 0.05 threshold, and applications to radiomics-reasons for a conservative approach. European radiology experimental 2020. link 3 . Self-assessment questions in diagnostic imaging. Neuroimaging clinics of North America 2004. link 4 Levin DC, Rao VM, Parker L, Maitino AJ, Sunshine JH. Who gets paid for diagnostic imaging, and how much?. Journal of the American College of Radiology : JACR 2004. link 5 Kisner HJ. Principles and clinical applications of image analysis. Clinics in laboratory medicine 1988. link 6 Lentle BC, Scott JR, Noujaim AA, Jackson FI. Iatrogenic alterations in radionuclide biodistributions. Seminars in nuclear medicine 1979. link80045-8)

    Original source

    1. [1]
      Diagnostic and interventional radiology: an update. — Giovagnoni A, De Filippo M, Barile A Acta bio-medica : Atenei Parmensis (2020)
    2. [2]
      Statistical significance: p value, 0.05 threshold, and applications to radiomics-reasons for a conservative approach. — Di Leo G, Sardanelli F European radiology experimental (2020)
    3. [3]
      Self-assessment questions in diagnostic imaging. Neuroimaging clinics of North America (2004)
    4. [4]
      Who gets paid for diagnostic imaging, and how much? — Levin DC, Rao VM, Parker L, Maitino AJ, Sunshine JH Journal of the American College of Radiology : JACR (2004)
    5. [5]
      Principles and clinical applications of image analysis. — Kisner HJ Clinics in laboratory medicine (1988)
    6. [6]
      Iatrogenic alterations in radionuclide biodistributions. — Lentle BC, Scott JR, Noujaim AA, Jackson FI Seminars in nuclear medicine (1979)
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