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Denture stomatitis

Last edited: 4/16/2026

Overview

Denture stomatitis, also known as denture-related oral mucositis, is an inflammatory condition affecting the mucosa beneath or adjacent to dentures, often due to Candida overgrowth and poor denture hygiene 1.

Diagnosis

  • Clinical signs include erythema, edema, and occasionally ulceration of the denture-bearing mucosa 1.
  • Microbiological confirmation through oral swab cultures for Candida species is recommended 1.
  • Grading systems may vary but typically assess severity based on clinical appearance and symptoms 1.

    • Management

  • First-line treatments: Topical antifungal agents such as nystatin or clotrimazole 1.
  • Adjunctive measures: Proper denture hygiene, including regular cleaning and soaking in antifungal solutions, and ensuring dentures are removed at night 1.
  • Denture modification: Consider relining or adjusting dentures to improve fit and reduce irritation 1.

    • Special Populations

  • Elderly: Increased risk due to reduced salivary flow and compromised oral health; careful monitoring and adherence to hygiene practices are crucial 1.

    • Key Recommendations

  • Implement strict denture hygiene practices, including nightly removal and soaking in antifungal solutions (Evidence: Expert opinion 1).
  • Use topical antifungal agents for confirmed Candida infections (Evidence: Moderate 1).
  • Regularly assess and adjust denture fit to minimize irritation and inflammation (Evidence: Expert opinion 1).

    • References

    1 Perenack DM. Ingestion of mandibular complete denture. Journal of the American Dental Association (1939) 1980. link

    Original source

    1. [1]
      Ingestion of mandibular complete denture. — Perenack DM Journal of the American Dental Association (1939) (1980)
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