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Dermatology2 papers

Malignant melanoma of palate

Last edited: 4/10/2026

Overview

Malignant melanoma is an aggressive and lethal form of skin cancer. Emerging evidence suggests that intermittent hypoxia, a feature of obstructive sleep apnea (OSA), may be associated with melanoma tumorigenesis 1.

Diagnosis

Management

Special Populations

Key Recommendations

  • Patients with obstructive sleep apnea (OSA) may have an increased incidence of melanoma compared to those without OSA 1.
  • References

    1 Tan NKW, Yap DWT, Tan BKJ, Teo YH, Tan EKH, Chan JY et al.. The association of obstructive sleep apnea with melanoma incidence and mortality: a meta-analysis of 5,276,451 patients. Sleep medicine 2021. link

    Original source

    1. [1]
      The association of obstructive sleep apnea with melanoma incidence and mortality: a meta-analysis of 5,276,451 patients.Tan NKW, Yap DWT, Tan BKJ, Teo YH, Tan EKH, Chan JY et al. Sleep medicine (2021)

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