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Obstetrics38 papers

Harmful pattern of use of methamphetamine

Last edited: 4/10/2026

Overview

Methamphetamine use is associated with significant adverse developmental outcomes in children exposed prenatally. Prenatal exposure may lead to alterations in brain microstructure and reduced subcortical volumes 1.

Diagnosis

Management

Special Populations

Pregnancy

Prenatal methamphetamine exposure is associated with adverse child developmental outcomes 1.

Key Recommendations

  • Prenatal methamphetamine exposure is associated with poorer intellectual functioning, problem-solving skills, short-term memory, and language development in children 1. (Evidence: Moderate)
  • Prenatal methamphetamine exposure may alter whole brain microstructure and reduce subcortical volumes in multiple brain regions 1. (Evidence: Moderate)
  • Further intervention studies are needed to identify effective prevention and harm minimization approaches for prenatal methamphetamine exposure 1. (Evidence: Expert opinion)

    • References

    1 Kunkler C, Lewis AJ, Almeida R. Methamphetamine exposure during pregnancy: A meta-analysis of child developmental outcomes. Neuroscience and biobehavioral reviews 2022. link

    Original source

    1. [1]
      Methamphetamine exposure during pregnancy: A meta-analysis of child developmental outcomes. — Kunkler C, Lewis AJ, Almeida R Neuroscience and biobehavioral reviews (2022)
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