← Back to guidelines
Cardiology10 papers

Prosthetic mitral valve failure requiring revision

Last edited: 4/10/2026

Overview

Prosthetic mitral valve failure can occur due to various reasons, necessitating revision surgery. Mitral valve repair (MVr) may offer superior long-term survival and freedom from valve-related complications compared to mitral valve replacement for primary mitral regurgitation 1.

Diagnosis

Management

  • Mitral valve repair (MVr) approaches include chordal replacement ("respect") and leaflet resection ("resect") 1.
  • The "respect" approach was associated with superior survival compared to the "resect" approach in an overall sample, but not in a risk-adjusted sample 1.
  • No difference was found between the "respect" and "resect" approaches in the rate of mitral regurgitation recurrence in either the overall or risk-adjusted samples 1.
  • Reoperation rates did not differ between the "respect" and "resect" approaches in the overall sample 1.
  • Special Populations

    Key Recommendations

  • Mitral valve repair (MVr) may be associated with superior long-term survival and freedom from valve-related complications compared with mitral valve replacement for primary mitral regurgitation 1. (Evidence: Moderate)
  • The chordal replacement ("respect") approach for mitral valve repair may be associated with superior survival compared to the leaflet resection ("resect") approach in an overall patient sample 1. (Evidence: Moderate)
  • There is no significant difference in the rate of mitral regurgitation recurrence between the "respect" and "resect" approaches for mitral valve repair 1. (Evidence: Moderate)
  • Reoperation rates do not appear to differ between the "respect" and "resect" approaches for mitral valve repair 1. (Evidence: Moderate)
  • References

    1 Caldonazo T, Sá MP, Jacquemyn X, Van den Eynde J, Kirov H, Harik L et al.. Respect Versus Resect Approaches for Mitral Valve Repair: A Meta-Analysis of Reconstructed Time-to-Event Data. The American journal of cardiology 2024. link

    Original source

    1. [1]
      Respect Versus Resect Approaches for Mitral Valve Repair: A Meta-Analysis of Reconstructed Time-to-Event Data.Caldonazo T, Sá MP, Jacquemyn X, Van den Eynde J, Kirov H, Harik L et al. The American journal of cardiology (2024)

    HemoChat

    by SPINAI

    Evidence-based clinical decision support powered by SNOMED-CT, Neo4j GraphRAG, and NASS/AO/NICE guidelines.

    ⚕ For clinical reference only. Not a substitute for professional judgment.

    © 2026 HemoChat. All rights reserved.
    Research·Pricing·Privacy & Terms·Refund·SNOMED-CT · NASS · AO Spine · NICE · GraphRAG