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Cardiology12 papers

Prosthetic aortic valve failure requiring revision

Last edited: 4/10/2026

Overview

Prosthetic aortic valve failure necessitates revision, with options including redo surgical aortic valve replacement (redo-SAVR) and valve-in-valve transcatheter aortic valve implantation (ViV-TAVI) 1. The choice between these techniques is debated, particularly given the increasing popularity of ViV-TAVI as a less invasive alternative 1.

Management

  • Valve-in-valve transcatheter aortic valve implantation (ViV-TAVI) demonstrated lower 1-year mortality, acute kidney injury, bleeding, stroke, and new pacemaker implantation compared to redo-SAVR 1.
  • Redo-SAVR showed more favorable mean postoperative aortic valve gradients 1.
  • Both redo-SAVR and ViV-TAVI exhibited similar procedural and short-term mortality 1.
  • Key Recommendations

  • Valve-in-valve transcatheter aortic valve implantation (ViV-TAVI) is associated with lower 1-year mortality, acute kidney injury, bleeding, stroke, and new pacemaker implantation compared to redo-SAVR 1. (Evidence: Moderate)
  • Redo surgical aortic valve replacement (redo-SAVR) may result in more favorable postoperative aortic valve gradients 1. (Evidence: Moderate)
  • Short-term mortality is similar between ViV-TAVI and redo-SAVR for failed bioprostheses 1. (Evidence: Moderate)
  • References

    1 Comentale G, Ahmadi-Hadad A, Moldon HJ, Carbone A, Manzo R, Franzone A et al.. Transcatheter aortic valve implantation vs. surgery for failed bioprosthesis: a meta-analysis of over 20 000 patients. Journal of cardiovascular medicine (Hagerstown, Md.) 2025. link

    Original source

    1. [1]
      Transcatheter aortic valve implantation vs. surgery for failed bioprosthesis: a meta-analysis of over 20 000 patients.Comentale G, Ahmadi-Hadad A, Moldon HJ, Carbone A, Manzo R, Franzone A et al. Journal of cardiovascular medicine (Hagerstown, Md.) (2025)

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