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Rheumatology45 papers

Nodular fasciitis

Last edited: 4/15/2026

Overview

Nodular fasciitis is a benign fibroblastic proliferation commonly found in soft tissues, characterized by rapid growth and self-limiting nature. It can occur in various locations, including unusual sites such as the scalp in newborns and oral cavity 12.

Diagnosis

  • Clinical Presentation: Sudden appearance of a small lump without obvious cause 2.
  • Histological Features: Characterized by proliferation of fibroblasts with a storiform pattern, often initially alarming but ultimately diagnostic of nodular fasciitis 2.
  • Imaging: Not typically required but may show a well-defined mass 12.
  • Biopsy: Essential for definitive diagnosis, distinguishing from sarcomas 2.
  • Management

  • Surgical Excision: Local removal is curative; recurrence is rare following complete excision 2.
  • No Additional Therapy: Generally no need for adjuvant treatments such as chemotherapy or radiation 2.
  • Special Populations

  • Pediatrics: Can occur in newborns, presenting as scalp lesions 1.
  • Recurrence: Not reported in pediatric cases within the follow-up period 1.
  • Key Recommendations

  • Perform a biopsy for definitive diagnosis to differentiate from malignant lesions (Evidence: Moderate 2).
  • Surgical excision is recommended for definitive treatment, with close follow-up to ensure no recurrence (Evidence: Moderate 2).
  • No adjuvant therapies are necessary following surgical removal (Evidence: Expert opinion 2).
  • References

    1 Barohn RJ, Kasdon DL. Cranial fasciitis: nodular fasciitis of the head. Surgical neurology 1980. link 2 Larsson A, Svartz K. Nodular fascitis in the oral cavity. International journal of oral surgery 1976. link80060-9)

    Original source

    1. [1]
      Cranial fasciitis: nodular fasciitis of the head.Barohn RJ, Kasdon DL Surgical neurology (1980)
    2. [2]
      Nodular fascitis in the oral cavity.Larsson A, Svartz K International journal of oral surgery (1976)

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