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Oncology131 papers

Intimal sarcoma

Last edited: 4/13/2026

Overview

Intimal sarcoma is a rare and aggressive malignancy arising from the intimal layer of blood vessels, often affecting large arteries and veins. It typically presents with local symptoms due to mass effect or embolization, and diagnosis requires a high index of suspicion given its rarity. 2349

Diagnosis

  • Imaging studies (CT, MRI, angiography) crucial for initial detection and characterization.
  • Histopathological confirmation required; biopsy often guided by imaging.
  • Immunohistochemistry aids in distinguishing from other vascular tumors. 2349
  • Management

  • Surgical resection when feasible, often combined with adjuvant therapies.
  • Radiation therapy may be used postoperatively or in unresectable cases.
  • Systemic chemotherapy regimens (e.g., gemcitabine, docetaxel) tailored based on multidisciplinary consensus. 2349
  • Special Populations

  • Pediatrics: Limited data; management typically involves multidisciplinary approaches similar to adults but with considerations for growth and development. 49
  • Elderly: Treatment strategies adjusted for comorbidities and functional status; less emphasis on aggressive interventions. 23
  • Comorbidities: Presence of significant comorbidities may influence treatment intensity, favoring less invasive or palliative approaches. 23
  • Key Recommendations

  • Early and accurate imaging for diagnosis, including CT, MRI, and angiography (Evidence: Moderate 23)
  • Multidisciplinary team approach for treatment planning, integrating surgical, radiological, and oncological expertise (Evidence: Expert opinion 49)
  • Consider adjuvant therapies (radiation, chemotherapy) based on tumor stage and resectability (Evidence: Moderate 23)
  • Tailor treatment to patient age and comorbidities, prioritizing quality of life in elderly or high-risk patients (Evidence: Expert opinion 23)
  • Regular follow-up with imaging to monitor for recurrence and metastasis (Evidence: Expert opinion 49)
  • References

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Academic Metrics and Demographics and National Institutes of Health Grant Funding in Interventional Radiology. Journal of vascular and interventional radiology : JVIR 2025. link 6 Malhotra A, Futela D, Khunte M, Wu X, Payabvash S, Gandhi D et al.. IR Physician Compensation at U.S. Medical Schools: Trends and Segments. Journal of vascular and interventional radiology : JVIR 2025. link 7 Stirrat T, Thiru S, Gao Y, Tran C, Baek G, Zhou A et al.. Gender disparities in authorship: A fifteen-year bibliometric analysis of interventional radiology journals. Current problems in diagnostic radiology 2025. link 8 Dewald CLA, Blum SFU, Becker LS, Barzakova E, Franke M, Westphalen K et al.. Exploring gender roles in German interventional radiology - how progressive are we?. RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin 2025. link 9 Dablan A, Özgül H, Kartal YC, Tekin AF. Comparative analysis of interventional radiology awareness: insights from Turkey, the USA, and Europe using Google Trends data. Clinical imaging 2025. link 10 Borse R, Irani Z. Interventional radiology for international medical graduates: Pathways, perspectives, and possibilities. Current problems in diagnostic radiology 2025. link 11 Schreiter J, Heinrich F, Hatscher B, Schott D, Hansen C. Multimodal human-computer interaction in interventional radiology and surgery: a systematic literature review. International journal of computer assisted radiology and surgery 2025. link 12 Lee C, Khunte M, Tegtmeyer K, Futela D, Bajaj S, Payabvash S et al.. Industry relationships with interventional radiologists: Who are the high payment physicians?. Current problems in diagnostic radiology 2025. link 13 Hunt ER, Vo S, Benson A, Thomas S, Dabbara H, Le RT. Female Representation in Integrated Interventional Radiology Residency: Trends, Underrepresentation, and Modest Growth Over Five Years. Journal of the American College of Radiology : JACR 2025. link 14 Ebel S, Ehrengut C, Denecke T, Gößmann H, Beeskow AB. GPT-4o’s competency in answering the simulated written European Board of Interventional Radiology exam compared to a medical student and experts in Germany and its ability to generate exam items on interventional radiology: a descriptive study. Journal of educational evaluation for health professions 2024. link 15 Islam M, Lee J, Huy B, Shanmugasundaram S, Kumar A, Shukla P. Association of Scholarly Impact to Industrial Contributions Among Academic Interventional Radiologists. Journal of the American College of Radiology : JACR 2024. link 16 Cao Y, Yu L, Xiong F, Wang J, Kan X, Zheng C. Longitudinal investigation of undergraduates' radiation anxiety, interest, and career intention in interventional radiology. European radiology 2024. link 17 Warren BE, Bilbily A, Gichoya JW, Conway A, Li B, Fawzy A et al.. An Introductory Guide to Artificial Intelligence in Interventional Radiology: Part 1 Foundational Knowledge. Canadian Association of Radiologists journal = Journal l'Association canadienne des radiologistes 2024. link 18 Alswang JM, Musa B, Ashraf N, Ahmad B, Mbuguje EM, Naif A et al.. Assessing interventional radiology specialty knowledge and perception amongst Tanzanian medical students before and after exposure to an immersive curriculum. Clinical radiology 2024. link 19 Khaja MS, Sabri SS. Status Report on the Integrated and Independent IR Residencies: Origins and Projections for the Future. Journal of vascular and interventional radiology : JVIR 2023. link 20 Matsumoto AH, Dake MD. Implications of IR Being a Primary Specialty on the Professional Organizational Relationship between Interventional and Diagnostic Radiology. Journal of vascular and interventional radiology : JVIR 2023. link 21 Higgins MCSS, Sun YL, Rochon PJ. Workforce Diversity of Interventional Radiology Physicians in North America: Reflections on the U.S. Experience. Canadian Association of Radiologists journal = Journal l'Association canadienne des radiologistes 2023. link 22 Cyphers ED, Groskreutz D, Grilli C, Ahuja RS. Exposure to IR Rotations in Osteopathic Medical Schools: Trends in Residency Applications and Matching. Journal of vascular and interventional radiology : JVIR 2023. link 23 McGinnis HD, Sze DY. The IR Trainee Workforce 10 Years after Becoming a Primary Medical Specialty. Journal of vascular and interventional radiology : JVIR 2023. link 24 Osman FH, Koe JSE, Lau ESW, Nagaraj D, Ng HH, Ng A et al.. The current status of interventional radiology in the undergraduate medical curriculum and the way forward. The British journal of radiology 2023. link 25 Garg T, Weiss CR, Gade TPF, Glasgow E, Palacios V, Doshi P et al.. Society of Interventional Radiology Foundation Funding to National Institutes of Health Funding: Report from the Society of Interventional Radiology Foundation/National Institutes of Health Task Force. Journal of vascular and interventional radiology : JVIR 2023. link 26 Mahay U, Jenkins P, Watkins L, Mandal I, Lewis O, Harborne KE et al.. Interventional radiology training in the UK: a view from within-a national survey. The British journal of radiology 2023. link 27 Shanmugasundaram S, Huy B, Shihora D, Lamparello N, Kumar A, Shukla P. Evaluation of h-index in Academic Interventional Radiology. Academic radiology 2023. link 28 Moriarty HK, Clements W, Zia A, Connor B, Goh GS. The gender imbalance in Interventional Radiology in Australia and New Zealand. Journal of medical imaging and radiation oncology 2023. link 29 Cheng JL, Park LS, Dibble EH, Baird GL, George PF, Ahn SH. Diversity in interventional radiology: Survey of medical student interest with focus on women and members of underrepresented in medicine racial and ethnic groups. Clinical imaging 2023. link 30 Osman FH, Koe JSE, Lau ESW, Nagaraj D, Ng HH, Ong LA et al.. Evaluation of learning and exposure in the undergraduate interventional radiology curriculum (ELIXIR). Clinical radiology 2023. link 31 Kim J, Kaylor K, Lamparello N. The Gender Gap in Interventional Radiology: Barriers, Opportunities, and the Role of the Integrated IR Residency. Academic radiology 2023. link 32 Jenkins P, MacCormick A, Harborne K, Liu W, Mahay U, Zhong J et al.. Barriers to research in interventional radiology within the UK. Clinical radiology 2022. link 33 Oladini LK, Rezaee M, Thukral S, Raiter S, Odetoyinbo K, Keller E et al.. Opportunities for Excellence in Interventional Radiology Training: A Qualitative Study. Journal of the American College of Radiology : JACR 2022. link 34 Khaja MS, Jo A, Sherk WM, Majdalany BS, Dunnick NR, Bailey JE et al.. Perspective on the New IR Residency Selection Process: 4-year Experience at a Large, Collaborative Training Program. Academic radiology 2022. link 35 Akii Bua A, Chinweze RO, Nwose S, Mohammed S. Perceptions of interventional radiology amongst international medical graduates. Clinical radiology 2022. link 36 Desai SB, Pareek A, Lungren MP. Current and emerging artificial intelligence applications for pediatric interventional radiology. Pediatric radiology 2022. link 37 Sieren M, Katoh M, Mahnken AH, Reimer P, Westphalen K, Hoffmann RT et al.. Work and Training Conditions of German Residents and Young Radiologists in Interventional Radiology - A Nationwide Survey. RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin 2022. link 38 Xiang DH, Snyder A, Capua JD, Galla N, Tischfield DJ, Lewis T et al.. Mentorship in Interventional Radiology: Addressing Obstacles to Pursuing Research and Innovation Among IR Trainees. Academic radiology 2022. link 39 Li O, Ross M, Wiseman D. Women in Interventional Radiology: Exploring the Gender Disparity in Canada. Current problems in diagnostic radiology 2021. link 40 Goldman D, Keller EJ. A Citizen of Two Worlds: The IR/DR Residency. Current problems in diagnostic radiology 2021. link 41 Parikh RS, Shamimi-Noori S, Reddy S, Gade T, Nadolski GJ, Hunt SJ. Demographic Trends in Female Interventional Radiology Trainees With the Advent of the Integrated Interventional Radiology Residency. Journal of the American College of Radiology : JACR 2021. link 42 Zeng CH, Lu J, Zhu HD, Teng GJ. Benchmark Status of Women Interventional Radiologists in China. Journal of vascular and interventional radiology : JVIR 2021. link 43 Park LS, Dibble EH, Baird GL, George P, Ahn SH. Considerations in Specialty Selections: What Medical Students Think, Know, and Think They Know about Interventional Radiology. Journal of vascular and interventional radiology : JVIR 2021. link 44 Xu Y, Pervez A, Theodoulou I, Zhong J, Lam S, Gkiousias V et al.. Future Interventional Radiologists and Where to Find Them-Insights from Five UK Interventional Radiology Symposia for Junior Doctors and Medical Students. Cardiovascular and interventional radiology 2021. link 45 Huasen B, Suwathep P, Khan A, Connor B, Holden A. Female medical student impression of interventional radiology: what can we do to improve this?. Diagnostic and interventional radiology (Ankara, Turkey) 2021. link 46 Wang MT, Foo M, Maingard J, Kok HK, Lamanna A, Jhamb A et al.. Social media in interventional radiology. Journal of medical imaging and radiation oncology 2021. link 47 Makris GC, Burrows V, Lyall F, Moore A, Hamady MS. Vascular and Interventional Radiology Training; International Perspectives and Challenges. Cardiovascular and interventional radiology 2021. link 48 Mandal I, Minocha A, Yeung J, Bandula S, Rabouhans J. Interventional radiology training: a comparison of 5 English-speaking countries. The British journal of radiology 2020. link 49 Duc NM, Ha HD, Thong PM. An Overview of Vietnamese Society of Interventional Radiology. Medical archives (Sarajevo, Bosnia and Herzegovina) 2020. link 50 Foo M, Maingard J, Wang M, Kok HK, Chandra RV, Jhamb A et al.. Women in interventional radiology: insights into Australia's gender gap. Clinical radiology 2020. link 51 Wadhwa V, Vilanilam GK, Malhotra A, Lamparello NA. Descriptive analysis of interventional radiology residency program directors in the United States. Clinical imaging 2020. link 52 Stoehr F, Schotten S, Pitton MB, Dueber C, Schmidt F, Hansen NL et al.. 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Expanding the Teaching Toolbox: Characterizing Utility of a Web-Based Lecture Series in Educating Future Colleagues and Referrers about the Field of IR. Journal of vascular and interventional radiology : JVIR 2019. link 58 Perez MG, Fassiotto M, Altamirano J, Hwang GL, Maldonado Y, Josephs S et al.. Untapped Resources: Attaining Equitable Representation for Women in IR. Journal of vascular and interventional radiology : JVIR 2019. link 59 Muzumdar S, Dayal S, Mohamed M, Sandhu S, Singh S, Walker P. Understanding the Awareness, Knowledge and Perceptions of Interventional Radiology Amongst Undergraduates in the UK. Cardiovascular and interventional radiology 2019. link 60 Makary MS, Rajan A, Miller RJ, Elliott ED, Spain JW, Guy GE. Institutional Interventional Radiology Symposium Increases Medical Student Interest and Identifies Target Recruitment Candidates. Current problems in diagnostic radiology 2019. link 61 Clements W, Goh GS, Nguyen J, Vrazas J, Rogan C, Lau G et al.. 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    Original source

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