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Toxicology4 papers

Nephropathy induced by amphotericin

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Management

In a retrospective study of 603 lung transplant recipients, only one patient (0.2%) discontinued iABLC therapy due to a drug-attributable adverse event [PMID:35506698].

Complications

Among 603 patients receiving iABLC prophylaxis, only one patient (0.2%) experienced a drug-attributable adverse event leading to discontinuation [PMID:35506698].

Prognosis & Follow-up

In the study cohort, one-year adverse events including rejection (68.7%), graft loss, and death (13.3%) matched national outcomes [PMID:35506698].

References

1 Huggins JP, Pease R, Stanly K, Workman A, Reynolds J, Alexander BD. Safety of Inhaled Amphotericin B Lipid Complex as Antifungal Prophylaxis in Lung Transplant Recipients. Antimicrobial agents and chemotherapy 2022. link

1 papers cited of 4 indexed.

Original source

  1. [1]
    Safety of Inhaled Amphotericin B Lipid Complex as Antifungal Prophylaxis in Lung Transplant Recipients.Huggins JP, Pease R, Stanly K, Workman A, Reynolds J, Alexander BD Antimicrobial agents and chemotherapy (2022)

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