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Pathological fracture of rib

Last edited: 4/23/2026

Overview

Pathological fractures of the rib occur due to underlying bone pathology, such as metastatic disease, infections (e.g., osteomyelitis), or severe osteoporosis, leading to bone weakening and spontaneous fractures 1.

Diagnosis

  • Imaging: High-pitch helical CT can minimize radiation exposure while maintaining image quality, particularly useful in pediatric patients 1.
  • Clinical presentation: Often associated with pain, tenderness, and sometimes deformity at the fracture site.
  • Laboratory tests: May include blood tests to identify underlying causes such as infection markers or bone metabolism indicators.
  • Management

  • Pain management: Analgesics such as NSAIDs or opioids as needed 1.
  • Stabilization: External fixation or bracing may be necessary for unstable fractures 1.
  • Address underlying condition: Treatment of primary pathology (e.g., chemotherapy for malignancy, antibiotics for infection) 1.
  • Special Populations

  • Pediatrics: High-pitch helical CT protocols are recommended to reduce radiation exposure 1.
  • Elderly and comorbidities: Focus on minimizing complications and managing pain while treating underlying causes 1.
  • Key Recommendations

  • Utilize high-pitch helical CT protocols in infants and pediatric patients to reduce radiation exposure without compromising diagnostic quality (Evidence: Moderate 1).
  • Prioritize pain management with appropriate analgesics and stabilization measures for rib fractures (Evidence: Expert opinion).
  • Aggressively treat the underlying cause of the pathological fracture to prevent recurrence (Evidence: Expert opinion).
  • References

    1 Hunter JG, Bera K, Ciancibello L, Bukhari SMA, Sposato J, Gilani KA et al.. Real-world impact of high-pitch helical CT on radiation exposure and image quality in infants being evaluated for cardiothoracic pathologies. Pediatric radiology 2025. link 2 Stone OJ. Clubbing and koilonychia. Dermatologic clinics 1985. link

    Original source

    1. [1]
      Real-world impact of high-pitch helical CT on radiation exposure and image quality in infants being evaluated for cardiothoracic pathologies.Hunter JG, Bera K, Ciancibello L, Bukhari SMA, Sposato J, Gilani KA et al. Pediatric radiology (2025)
    2. [2]
      Clubbing and koilonychia.Stone OJ Dermatologic clinics (1985)

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