Overview
Inflammatory pseudotumor (IPT) of the liver is a rare, benign lesion of unknown etiology often presenting with fever and mimicking neoplastic processes 2.Diagnosis
Imaging findings: Hypodense mass on CT, enhanced on MRI 2
Diagnostic confirmation: US-guided needle biopsy 3
Associated symptoms: Persistent unexplained fever 2Management
Surgical resection: Effective for definitive diagnosis and treatment 23
Adjunctive therapy: Corticosteroids may be considered for symptom management, though specific dosing is not detailed 2Special Populations
Comorbidities: Possible interaction noted with recurrent gouty arthritis 2Key Recommendations
Perform imaging studies (CT, MRI) for diagnosis and characterization of liver IPT masses (Evidence: Moderate 2)
Consider surgical excision for definitive treatment and resolution of symptoms (Evidence: Moderate 23)
Evaluate for and manage comorbid conditions that may interact with IPT, such as recurrent gouty arthritis (Evidence: Weak 2)References
1 Mehta V, Torkian BA, Daines SM, Kelly TF. Otolaryngologists and orbital pseudotumor: a case report. Ear, nose, & throat journal 2008. link
2 Takahashi T, Haneda T, Nagano T, Kawahito Y, Mori Y, Senga K et al.. Inflammatory pseudotumor of the liver complicated with recurrent gouty arthritis. Internal medicine (Tokyo, Japan) 2001. link
3 Irie H, Muranaka T, Nanjo T, Hanada K, Oshiumi Y. Inflammatory pseudotumor of the liver. Radiation medicine 1989. link