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Orthopedics49 papers

Arthritis of glenohumeral joint

Last edited: 4/14/2026

Overview

Glenohumeral arthritis involves degenerative changes in the shoulder joint, leading to pain, stiffness, and functional impairment. Management varies based on patient age, severity, and associated rotator cuff status 127.

Diagnosis

  • Clinical Presentation: Pain, crepitus, weakness, and reduced range of motion 7.
  • Imaging: Radiographs showing osteophyte formation, sclerosis, superior humeral head migration, and bony erosion 7.
  • Advanced Imaging: MRI or ultrasound to assess rotator cuff integrity, tear size, and fatty infiltration 37.
  • Management

  • Nonoperative: Physical therapy, corticosteroid injections, and NSAIDs for pain management 7.
  • Surgical Options:
  • - Total Shoulder Arthroplasty (TSA): Preferred for intact rotator cuffs 2. - Hemiarthroplasty: Suitable for severe rotator cuff deficiency 9. - Reverse Shoulder Prosthesis: Effective for irreparable rotator cuff tears 68.
  • Biologic Resurfacing: Emerging option for younger patients with glenohumeral arthritis 4.
  • Special Populations

  • Elderly Patients: Reverse shoulder arthroplasty shows promising short-term outcomes for severe rotator cuff deficiency 68.
  • Rotator Cuff Deficiency: Hemiarthroplasty and reverse shoulder prosthesis are key interventions 97.
  • Key Recommendations

  • Assess Rotator Cuff Integrity: Use advanced imaging (MRI, ultrasound) preoperatively to guide prosthesis choice (TSA vs. RSA) 3. (Evidence: Moderate)
  • Consider Reverse Shoulder Prosthesis: For patients with severe rotator cuff deficiency, reverse shoulder arthroplasty offers effective pain relief and functional improvement 68. (Evidence: Moderate)
  • Evaluate Patient Age and Arthritis Severity: Younger patients may benefit from biologic resurfacing, while older patients with severe arthritis may require prosthetic replacement 4. (Evidence: Expert opinion)
  • References

    1 Colasanti CA, Lin CC, Simovitch RW, Virk MS, Zuckerman JD. International consensus statement on the management of glenohumeral arthritis in patients ≤ 50 years old. Journal of shoulder and elbow surgery 2023. link 2 Singh Jagdev B, McGrath J, Cole A, Gomaa AR, Chong HH, Singh HP. Total shoulder arthroplasty vs. hemiarthroplasty in patients with primary glenohumeral arthritis with intact rotator cuff: meta-analysis using the ratio of means. Journal of shoulder and elbow surgery 2022. link 3 Levin JM, Wickman J, Lazarides AL, Cunningham DJ, Goltz DE, Mather RC et al.. Is Advanced Imaging to Assess Rotator Cuff Integrity Before Shoulder Arthroplasty Cost-effective? A Decision Modeling Study. Clinical orthopaedics and related research 2022. link 4 Burkhead WZ, Krishnan SG, Lin KC. Biologic resurfacing of the arthritic glenohumeral joint: Historical review and current applications. Journal of shoulder and elbow surgery 2007. link 5 Gutiérrez S, Greiwe RM, Frankle MA, Siegal S, Lee WE. Biomechanical comparison of component position and hardware failure in the reverse shoulder prosthesis. Journal of shoulder and elbow surgery 2007. link 6 Frankle M, Levy JC, Pupello D, Siegal S, Saleem A, Mighell M et al.. The reverse shoulder prosthesis for glenohumeral arthritis associated with severe rotator cuff deficiency. a minimum two-year follow-up study of sixty patients surgical technique. The Journal of bone and joint surgery. American volume 2006. link 7 Laudicina L, D'Ambrosia R. Management of irreparable rotator cuff tears and glenohumeral arthritis. Orthopedics 2005. link 8 Frankle M, Siegal S, Pupello D, Saleem A, Mighell M, Vasey M. The Reverse Shoulder Prosthesis for glenohumeral arthritis associated with severe rotator cuff deficiency. A minimum two-year follow-up study of sixty patients. The Journal of bone and joint surgery. American volume 2005. link 9 Sanchez-Sotelo J, Cofield RH, Rowland CM. Shoulder hemiarthroplasty for glenohumeral arthritis associated with severe rotator cuff deficiency. The Journal of bone and joint surgery. American volume 2001. link

    Original source

    1. [1]
      International consensus statement on the management of glenohumeral arthritis in patients ≤ 50 years old.Colasanti CA, Lin CC, Simovitch RW, Virk MS, Zuckerman JD Journal of shoulder and elbow surgery (2023)
    2. [2]
      Total shoulder arthroplasty vs. hemiarthroplasty in patients with primary glenohumeral arthritis with intact rotator cuff: meta-analysis using the ratio of means.Singh Jagdev B, McGrath J, Cole A, Gomaa AR, Chong HH, Singh HP Journal of shoulder and elbow surgery (2022)
    3. [3]
      Is Advanced Imaging to Assess Rotator Cuff Integrity Before Shoulder Arthroplasty Cost-effective? A Decision Modeling Study.Levin JM, Wickman J, Lazarides AL, Cunningham DJ, Goltz DE, Mather RC et al. Clinical orthopaedics and related research (2022)
    4. [4]
      Biologic resurfacing of the arthritic glenohumeral joint: Historical review and current applications.Burkhead WZ, Krishnan SG, Lin KC Journal of shoulder and elbow surgery (2007)
    5. [5]
      Biomechanical comparison of component position and hardware failure in the reverse shoulder prosthesis.Gutiérrez S, Greiwe RM, Frankle MA, Siegal S, Lee WE Journal of shoulder and elbow surgery (2007)
    6. [6]
      The reverse shoulder prosthesis for glenohumeral arthritis associated with severe rotator cuff deficiency. a minimum two-year follow-up study of sixty patients surgical technique.Frankle M, Levy JC, Pupello D, Siegal S, Saleem A, Mighell M et al. The Journal of bone and joint surgery. American volume (2006)
    7. [7]
      Management of irreparable rotator cuff tears and glenohumeral arthritis.Laudicina L, D'Ambrosia R Orthopedics (2005)
    8. [8]
      The Reverse Shoulder Prosthesis for glenohumeral arthritis associated with severe rotator cuff deficiency. A minimum two-year follow-up study of sixty patients.Frankle M, Siegal S, Pupello D, Saleem A, Mighell M, Vasey M The Journal of bone and joint surgery. American volume (2005)
    9. [9]
      Shoulder hemiarthroplasty for glenohumeral arthritis associated with severe rotator cuff deficiency.Sanchez-Sotelo J, Cofield RH, Rowland CM The Journal of bone and joint surgery. American volume (2001)

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