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Congenital dysplasia of cardiac valve

Last edited: 4/22/2026

Overview

Congenital dysplasia of the cardiac valve, particularly the tricuspid valve, involves abnormal development leading to structural defects such as thickened leaflets, fused chordae tendineae, and papillary muscle hypertrophy, often associated with regurgitation and heart chamber dilation. 12

Diagnosis

  • Clinical Signs: Tachycardia, tachypnea, dyspnea, and murmurs (right apical systolic murmur).
  • Imaging: Thoracic radiographs showing cardiomegaly, echocardiography for detailed valve assessment.
  • Key Findings: Tricuspid valve dysplasia, severe tricuspid regurgitation, right-heart dilation, patent foramen ovale.
  • Additional Anomalies: May include mitral valve malformations, ventricular septal defects, and other congenital heart anomalies. 12
  • Management

  • Surgical Intervention: Indicated for severe cases with significant regurgitation and hemodynamic compromise.
  • Medical Management: Supportive care including diuretics and afterload reduction agents (e.g., vasodilators) as needed.
  • Monitoring: Regular echocardiographic follow-up to assess valve function and heart chamber dimensions.
  • Specific Drug Classes: No specific doses mentioned; tailored based on clinical response. 1
  • Special Populations

  • Pediatrics: Early diagnosis via echocardiography crucial for managing congenital defects effectively. 1
  • Comorbidities: Presence of additional cardiac anomalies may complicate management and require multidisciplinary approaches. 2
  • Key Recommendations

  • Utilize echocardiography for definitive diagnosis of tricuspid valve dysplasia and associated anomalies (Evidence: Moderate 12)
  • Consider surgical intervention for severe cases with hemodynamic instability (Evidence: Expert opinion 1)
  • Implement supportive medical management including diuretics and afterload reduction as indicated (Evidence: Weak 1)
  • References

    1 Dias Moreira AS, Grint K, Stepien R, Shaw G, Peek S. Tricuspid valve dysplasia and a patent foramen ovale resulting in severe tricuspid regurgitation and right-heart dilation in a Red Angus calf. Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology 2019. link 2 Liu SK, Tilley LP. Dysplasia of the tricuspid valve in the dog and cat. Journal of the American Veterinary Medical Association 1976. link

    Original source

    1. [1]
      Tricuspid valve dysplasia and a patent foramen ovale resulting in severe tricuspid regurgitation and right-heart dilation in a Red Angus calf.Dias Moreira AS, Grint K, Stepien R, Shaw G, Peek S Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology (2019)
    2. [2]
      Dysplasia of the tricuspid valve in the dog and cat.Liu SK, Tilley LP Journal of the American Veterinary Medical Association (1976)

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