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Neurosurgery6 papers

Arthritis of lumbosacral spine

Last edited: 4/16/2026

Overview

Degenerative arthritis of the lumbosacral spine involves structural changes in the intervertebral discs and facet joints, leading to pain, stiffness, and functional impairment. Minimally invasive surgical techniques, such as transforaminal lumbar interbody fusion (MI-TLIF), are increasingly utilized to address severe cases 1.

Diagnosis

  • Clinical Presentation: Persistent lower back pain, radiculopathy, and functional disability 1.
  • Imaging Studies: MRI and CT scans essential for identifying disc degeneration, spinal stenosis, and instability 1.
  • Functional Assessment: Oswestry Disability Index (ODI) and SF-36 scores to quantify disability and quality of life 1.
  • Management

  • Non-Surgical: Physical therapy, weight management, NSAIDs (e.g., ibuprofen 400-800 mg qid), and muscle relaxants 1.
  • Surgical: MI-TLIF with percutaneous bilateral pedicle screw fixation for refractory cases 1.
  • Post-Surgical Rehabilitation: Early mobilization and structured physical therapy to improve outcomes 1.
  • Special Populations

  • Elderly: MI-TLIF can be effective but requires careful assessment of comorbidities and surgical risk 1.
  • Comorbidities: Patients with significant comorbidities may benefit from less invasive approaches if surgical intervention is necessary 1.
  • Key Recommendations

  • Consider MI-TLIF for Severe Degenerative Lumbosacral Disease: Minimally invasive techniques show potential advantages in managing refractory cases (Evidence: Moderate 1).
  • Assess Functional Outcomes Using ODI and SF-36: Regular evaluation of disability and quality of life post-treatment is crucial (Evidence: Moderate 1).
  • Tailor Surgical Approach Based on Patient Comorbidities: Individualize surgical intervention considering patient-specific risks (Evidence: Expert opinion 1).
  • References

    1 Millimaggi DF, Norcia VD, Luzzi S, Alfiero T, Galzio RJ, Ricci A. Minimally Invasive Transforaminal Lumbar Interbody Fusion with Percutaneous Bilateral Pedicle Screw Fixation for Lumbosacral Spine Degenerative Diseases. A Retrospective Database of 40 Consecutive Cases and Literature Review. Turkish neurosurgery 2018. link

    Original source

    1. [1]

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