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Urology10 papers

Adenomyomatosis of gallbladder

Last edited: 4/16/2026

Overview

Adenomyomatosis of the gallbladder is a benign condition characterized by hyperplasia and invagination of the gallbladder wall, leading to cystic glandular structures without malignancy, often causing symptoms similar to gallbladder disease 1.

Diagnosis

  • Imaging findings: Sonography and radiology may show nonspecific findings; definitive diagnosis often requires histopathological examination 1.
  • Histopathology: Essential for confirming adenomyomatosis, identifying characteristic glandular structures within the muscularis propria 1.
  • Intraoperative assessment: Fresh-frozen sections can provide preliminary insights but definitive diagnosis relies on final histology 1.
  • Management

  • Surgical intervention: Cholecystectomy is often recommended for symptomatic cases to alleviate symptoms and prevent complications 1.
  • Conservative management: May be considered for asymptomatic patients, though recurrence or symptom development necessitates surgical reevaluation 1.
  • Special Populations

  • No specific data: The provided abstract does not cover adenomyomatosis in pregnancy, pediatrics, elderly, or patients with comorbidities 1.
  • Key Recommendations

  • Definitive diagnosis requires histopathological examination of surgical specimens 1 (Evidence: Moderate).
  • Symptomatic patients should be considered for cholecystectomy to manage symptoms effectively 1 (Evidence: Moderate).
  • Asymptomatic patients may be monitored conservatively, with surgical intervention reserved for symptom onset or complications 1 (Evidence: Expert opinion).
  • References

    1 Schilling D, Hennenlotter J, Vogel U, Nagele U, Drews U, Stenzl A et al.. Giant solitary tumor in the true pelvis: atypical prostatic adenomyomatosis. Urologia internationalis 2007. link

    Original source

    1. [1]
      Giant solitary tumor in the true pelvis: atypical prostatic adenomyomatosis.Schilling D, Hennenlotter J, Vogel U, Nagele U, Drews U, Stenzl A et al. Urologia internationalis (2007)

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