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Psychiatry7 papers

Secondary tic disorder

Last edited: 4/10/2026

Overview

Secondary tic disorders are characterized by the presence of tics that are caused by a known medical condition or substance use. These tics are typically persistent and can significantly impact a patient's quality of life.

Diagnosis

  • Tics are sudden, rapid, recurrent, non-rhythmic motor movements or vocalizations 1.
  • Diagnosis requires the presence of tics that are attributable to the physiological effects of a substance or another medical condition 1.
  • Diagnostic evaluation may include a thorough medical history, physical examination, and potentially neuroimaging or laboratory tests to rule out underlying causes 1.
  • Management

  • Psychoeducation is recommended as an initial intervention for tic disorders, regardless of symptom severity 1.
  • Habit Reversal Training (HRT), particularly the Comprehensive Behavioral Intervention for Tics (CBIT) package, has the most evidence for efficacy 1.
  • Exposure and Response Prevention (ERP) is also recommended, though with a lesser degree of certainty than HRT/CBIT due to fewer studies 1.
  • Cognitive interventions and third-wave interventions are not recommended as stand-alone treatments 1.
  • Videoconference delivery of HRT/CBIT is the most evaluated novel treatment delivery format 1.
  • Key Recommendations

  • Psychoeducation is recommended as an initial intervention for tic disorders 1. (Evidence: Expert opinion)
  • Habit Reversal Training (HRT), including Comprehensive Behavioral Intervention for Tics (CBIT), is recommended for tic disorders 1. (Evidence: Moderate)
  • Exposure and Response Prevention (ERP) is recommended for tic disorders, though with less certainty than HRT/CBIT 1. (Evidence: Weak)
  • References

    1 Andrén P, Jakubovski E, Murphy TL, Woitecki K, Tarnok Z, Zimmerman-Brenner S et al.. European clinical guidelines for Tourette syndrome and other tic disorders-version 2.0. Part II: psychological interventions. European child & adolescent psychiatry 2022. link

    Original source

    1. [1]
      European clinical guidelines for Tourette syndrome and other tic disorders-version 2.0. Part II: psychological interventions.Andrén P, Jakubovski E, Murphy TL, Woitecki K, Tarnok Z, Zimmerman-Brenner S et al. European child & adolescent psychiatry (2022)

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