Overview
Megalocornea is a rare, non-progressive congenital condition characterized by an enlarged cornea (typically >13 mm diameter) with normal corneal thickness and clear stroma 1. It is often associated with an enlarged anterior chamber and an extended ciliary ring, and may present with early cataracts and zonular anomalies 1.Diagnosis
Management
Surgical approaches for cataract surgery in megalocornea include phacoemulsification (62.1%) and extracapsular cataract extraction (33.3%) 1.
Intraocular lens (IOL) displacement occurred in 25% of cases, and further surgery was required in 21.5% 1.
Despite risks, appropriate IOL selection and surgical techniques can lead to favorable visual outcomes 1.Special Populations
Key Recommendations
Megalocornea presents unique challenges during cataract surgery, particularly regarding the risk of IOL displacement due to zonular weakness and capsular enlargement 1. (Evidence: Moderate)
Phacoemulsification and extracapsular cataract extraction are common surgical approaches for cataract surgery in megalocornea 1. (Evidence: Moderate)
Careful IOL selection and surgical technique are crucial to achieve favorable visual outcomes in patients with megalocornea undergoing cataract surgery 1. (Evidence: Moderate)References
1 Vaccaro S, Ventura M, Passaro ML, Ferrara M, Semeraro F, Dhubhghaill SN et al.. Cataract surgery in megalocornea: A qualitative and quantitative evaluation of published literature. Acta ophthalmologica 2025. link