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Dermatology71 papers

Trichodysplasia spinulosa caused by Polyomavirus

Last edited: 4/16/2026

Overview

Trichodysplasia spinulosa, often associated with Polyomavirus infection, is a rare dermatological condition characterized by hyperkeratotic papules and follicular plugging, typically affecting immunocompromised individuals 1.

Diagnosis

  • Clinical presentation of hyperkeratotic papules and follicular spicules 1.
  • Histopathological examination may confirm characteristic features including hyperkeratosis and trichodysplasia 1.
  • Polymerase chain reaction (PCR) testing for Polyomavirus can aid in diagnosis 1.

    • Management

  • First-line treatment: Use of hydroactive adhesive pads (e.g., Biore) for "deep cleaning" to manage symptoms 1.
  • Adjunctive treatments: No specific adjunctive treatments mentioned in the provided abstracts 1.

    • Special Populations

  • Immunocompromised individuals: Particularly susceptible; management focuses on supportive care and addressing underlying immunosuppression 1.
  • No specific guidance provided for pregnancy, pediatrics, elderly, or comorbidities in the given abstracts 1.

    • Key Recommendations

  • Utilize hydroactive adhesive pads for symptomatic relief in managing trichodysplasia spinulosa (Evidence: Expert opinion) 1.
  • Consider histopathological examination and PCR testing for Polyomavirus to confirm diagnosis (Evidence: Expert opinion) 1.
  • Focus on supportive care and addressing underlying immunosuppression in immunocompromised patients (Evidence: Expert opinion) 1.

    • References

    1 Elston DM, White LC. Treatment of trichostasis spinulosa with a hydroactive adhesive pad. Cutis 2000. link

    Original source

    1. [1]
      Treatment of trichostasis spinulosa with a hydroactive adhesive pad. — Elston DM, White LC Cutis (2000)
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