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Anesthesiology6 papers

Delirium caused by dissociative drug

Last edited: 4/15/2026

Overview

Delirium caused by dissociative drugs involves acute changes in mental status characterized by confusion, altered perception, and fluctuating consciousness, often seen acutely following drug use. 1 does not directly address delirium but provides insights into sedative effects relevant to understanding altered mental states.

Diagnosis

  • Assess acute onset of confusion and altered perception.
  • Evaluate for fluctuating levels of consciousness.
  • Consider history of dissociative drug use.
  • No specific diagnostic tests mentioned in provided abstracts; clinical assessment is key. 1
  • Management

  • Supportive care including environmental modifications to reduce sensory overload.
  • Monitoring for and treating underlying causes or complications.
  • Specific pharmacological interventions not detailed in provided abstracts; focus on symptom management. 1
  • Special Populations

  • No specific data provided for pregnancy, pediatrics, elderly, or comorbidities related to delirium from dissociative drugs in the given abstracts. 1
  • Key Recommendations

  • Prioritize clinical assessment over specific pharmacological interventions for delirium caused by dissociative drugs due to limited evidence in the provided studies. (Evidence: Expert opinion) 1
  • Consider environmental adjustments to minimize sensory stimuli in managing patients experiencing delirium post-drug use. (Evidence: Expert opinion) 1
  • Monitor for and address any acute physiological complications alongside psychiatric symptoms, given the acute nature of drug-induced delirium. (Evidence: Expert opinion) 1
  • References

    1 Elvir Lazo OL, White PF, Tang J, Yumul R, Cao X, Yumul F et al.. Propofol versus midazolam for premedication: a placebo‑controlled, randomized double‑blinded study. Minerva anestesiologica 2016. link 2 Eguchi T, Li HY, Kazami J, Kakinuma K, Otake N. Intermolecular stacking of gilvocarcin V tetraacetate as evidenced by nuclear magnetic resonance studies. The Journal of antibiotics 1990. link

    Original source

    1. [1]
      Propofol versus midazolam for premedication: a placebo‑controlled, randomized double‑blinded study.Elvir Lazo OL, White PF, Tang J, Yumul R, Cao X, Yumul F et al. Minerva anestesiologica (2016)
    2. [2]
      Intermolecular stacking of gilvocarcin V tetraacetate as evidenced by nuclear magnetic resonance studies.Eguchi T, Li HY, Kazami J, Kakinuma K, Otake N The Journal of antibiotics (1990)

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