Polyneuropathy caused by drug

Overview

Diagnosis

Management

Special Populations

Key Recommendations

References

Showing 100 most recent of 497 indexed papers.

1 Liang J, Brand L, Ruiter R, Smit PW, Vos CNF, van der Vlugt JJB et al.. Pharmacogenomics-guided personalized medicine in a clinical setting: real-world data. Pharmacogenetics and genomics 2026. link 2 Valz Gris A, Farina S, Porcelli M, Di Pumpo M, Farina A, Ricciardi W et al.. Polypharmacy management interventions in older adults: An umbrella review of meta-analyses of randomized controlled trials. Public health 2026. link 3 Adebisi YA, Alshahrani NZ, Bafail DA. Socioeconomic deprivation and its association with polypharmacy in England: results from a national cross-sectional survey. International journal of clinical pharmacy 2026. link 4 Huon JF, Blanchard B, Spiesser-Robelet L, Mongaret C, Chaumais MC, Nizet P. Evaluation of the Perception of Deprescribing by French Pharmacy Students: A National Observational Study. Basic & clinical pharmacology & toxicology 2026. link 5 Duncan LJ, McCahon D, Caddick B, Parslow RM, Turner K, Chew-Graham CA et al.. Patients' experiences of a patient-centred polypharmacy medication review intervention: a mixed-methods study. The British journal of general practice : the journal of the Royal College of General Practitioners 2026. link 6 Roa Santervas L, Skovlund E, Kristoffersen ES, Ringstad IB, Fjeld KG, Hove LH et al.. Collaborative medication reviews during acute primary care admissions for older adults with polypharmacy: a randomised controlled trial. Age and ageing 2026. link 7 Christensen LWS, El Gamah I, Barre AOI, Moga DC, Aharaz A, Bornæs O et al.. Patients' Attitudes Towards Deprescribing and Associations With Patient-Related Factors Across Two Hospital Settings. Basic & clinical pharmacology & toxicology 2026. link 8 Baas G, Heringa M, Verdoorn S, Kwint HF, Badawy E, Gussekloo J et al.. A Clinical Medication Review Focused on Deprescribing in Older Patients With Hyperpolypharmacy: A Mixed-Methods Feasibility Study. Basic & clinical pharmacology & toxicology 2026. link 9 Ouraou R, Cossette B, Perron ME, Hudon C. Pharmacists' role in interventions addressing excessive polypharmacy: a scoping review. International journal of clinical pharmacy 2026. link 10 Schmidt J, Lampe D, Poppe A, Meyer I, Söling S, Köberlein-Neu J et al.. Enhancing Continuous Medication Safety Through e-Prescription and Clinical Decision Support Systems in Outpatient Practices and Pharmacies: Protocol for a Multiperspective Study (eRIKA Study). JMIR research protocols 2026. link 11 Osińska M, Meyer-Massetti C, Welte N, Zúñiga F. Difficulties measuring a polypharmacy quality indicator in Switzerland's residential long-term care institutions - a mixed-methods study. Geriatric nursing (New York, N.Y.) 2026. link 12 Parodi López N, Thulesius H, Mannheimer S, Jungo KT, Weir KR, Rozsnyai Z et al.. Patients' perspectives on deprescribing in swedish primary care: an exploratory survey study. Scandinavian journal of primary health care 2026. link 13 Chae H, Ah YM, Jang S, Jang S, Lee HJ, Kim JH et al.. Resolving Medication-Related Problems in Older Adults through a Multidisciplinary Approach in Korea's Hospital-Based Polypharmacy Program. Yonsei medical journal 2026. link 14 Sloan CE, Ashner MC, McDermott CL, Burrows BT, Pieper C, Bhatt AS et al.. Association Between Polypharmacy and Physical Function in Middle-aged Adults: Findings from the CARDIA Function Study. Journal of general internal medicine 2026. link 15 Kim SW, Baek JY, Lee M, Han SG, Kim WY, Kim D et al.. Exploring the Barriers and Facilitators of Deprescribing in Older Adults: Qualitative Study of Patients and Geriatrics Experts. Journal of Korean medical science 2025. link 16 Tejani AM, Perry TL. Reducing prescribing cascades. African journal of primary health care & family medicine 2025. link 17 Megerlin F, Bouvenot G, Queneau P. Drug deprescribing policy and incentives in France. Annales pharmaceutiques francaises 2025. link 18 Stingl JC, Viviani R. Pharmacogenetic guided drug therapy - how to deal with phenoconversion in polypharmacy. Expert opinion on drug metabolism & toxicology 2025. link 19 Hamed N, Bates C, Khan MU, Maidment I. Realist review: understanding the challenges of medicine optimisation among older people from ethnic minority communities with polypharmacy in primary care. BMC geriatrics 2025. link 20 Blease J, Bhonsle Y, Ireson R, Farroha A, Westley G, Cooper R et al.. The role of community pharmacists in medicines optimisation for housebound people: A scoping review. PloS one 2025. link 21 Ie K, Machino R, Albert SM, Tomita S, Ohashi H, Motohashi I et al.. Proactive Deprescribing Among Older Adults With Polypharmacy: Barriers and Enablers. Annals of family medicine 2025. link 22 Als JG, Thomsen JL, Sørensen SS, Johnsen SP, Merrild CH. 'You would rather not fill your body with pills'-patient perspectives on polypharmacy and medication reviews by pharmacists in general practice. Scandinavian journal of primary health care 2025. link 23 Kallis TJ, Mattick K, Scott J, Payne RA. How do pharmacists navigate clinical uncertainty when reviewing polypharmacy? A critical literature review. BMC primary care 2025. link 24 Hamed N, Bates C, Khan MU, Maidment I. Understanding the challenges of medicine optimisation among older people (aged 60 years and above) from ethnic minority communities with polypharmacy in primary care: a realist review protocol. Systematic reviews 2025. link 25 Dalton K, Evrard P, Moriarty F, O'Mahony A, Horan R, Byrne S et al.. How are prescribing cascades defined in the literature? A scoping review. Research in social & administrative pharmacy : RSAP 2025. link 26 Szoszkiewicz M, Deskur-Śmielecka E, Styszyński A, Kusyń M, Krzemińska K, Więckowska B et al.. The hidden risks of polypharmacy: Exploring potentially inappropriate prescribing with STOPP/START criteria version 3-A cross-sectional study. PloS one 2025. link 27 Karimi R, Robinson-Barella A, Davey V, Sinclair DR, Hanratty B, Todd A. Understanding polypharmacy for people receiving home care services: a scoping review of the evidence. Age and ageing 2025. link 28 Tenzek KE, Chen HW, Brady LA, Wurst C, Cosmai M, Carlson J et al.. Doctor-Patient Deprescribing Conversations: A Multidisciplinary Analysis of Quality Assurance Recordings. Basic & clinical pharmacology & toxicology 2025. link 29 Mouazer A, Dubois S, Léguillon R, Boudegzdame N, Levrard T, Le Bars Y et al.. A simulation trial evaluating ABiMed, a clinical decision support system for medication reviews and polypharmacy management. Research in social & administrative pharmacy : RSAP 2025. link 30 Omuya H, Welch L, Raňola TS, McConnell ME, Malta JS, Genisot A et al.. Enhancing older Veterans' care: Insights from medication reviews and deprescribing interventions. Research in social & administrative pharmacy : RSAP 2025. link 31 Fallis S, Lam I, McCarthy L, Sergeant M. Polypharmacy: Institutional Approaches to Support Patients, Systems and the Climate. Healthcare quarterly (Toronto, Ont.) 2025. link 32 Zhao Z, Zhao Y, Hu X, Wang X, Wang G, Zhang X et al.. Use of Drugs With Actionable Pharmacogenetic Biomarkers and Possible Prescribing Changes Among Older People. Journal of the American Geriatrics Society 2025. link 33 Dumitrescu I, Casteels M, De Vliegher K, Hubens C, Dilles T. Home Care Patient's Experiences and Medication Burden Related to High-Risk Medication Use: A Cross-Sectional Study. International journal of older people nursing 2025. link 34 Doherty AS, Lund LC, Moriarty F, Boland F, Clyne B, Fahey T et al.. Prescribing Cascades Among Older Community-Dwelling Adults: Application of Prescription Sequence Symmetry Analysis to a National Database in Ireland. Annals of family medicine 2025. link 35 Modesto ACF, Lopes LPN, Neiva Pantuzza LL, Moura MDG, de Oliveira JC, Lopes LC. Instruments for assessing healthcare professionals' knowledge, attitudes and practices regarding deprescribing: a scoping review protocol. BMJ open 2025. link 36 Okati L, Lo S, Gnjidic D, Li SJ, Thillainadesan J. Mobile applications on app stores for deprescribing: A scoping review. British journal of clinical pharmacology 2025. link 37 Rochon PA, Li J, O'Mahony D, Onder G, Petrovic M, Sternberg SA et al.. The impact of age, sex, and gender on polypharmacy and potential prescribing cascades: Lessons from five databases. Journal of the American Geriatrics Society 2025. link 38 Mair A, Kirke C, Scott MG, Micheal N, Law S, Kanan Y et al.. iSIMPATHY: a multinational pre-post non-randomised intervention study transforming medication review. BMJ open 2025. link 39 Kaae S, Holst SS, Hansen JM, Vermehren C. New program theory in pharmacist-led patient-centered medication review in general practice: A qualitative pilot study. Research in social & administrative pharmacy : RSAP 2025. link 40 Song J, Huang J, Mao J, Cao J, Zhao Q. Analysis of a medication discrepancy management platform in reducing medication discrepancy and influencing factors among elderly patients with polypharmacy. European journal of clinical pharmacology 2025. link 41 Engels L, van den Akker M, Denig P, Stoffers H, Gerger H, Bohnen J et al.. Medication Management in Patients With Polypharmacy in Primary Care: A Scoping Review of Clinical Practice Guidelines. Journal of evidence-based medicine 2025. link 42 Vamadevan A, Vijayan V, Cole C, Jayasudha K, Yusuf N, Walker LE. A NASSS framework-guided systematic review and exploratory modelling of digital health interventions for polypharmacy management in older adults. BMC geriatrics 2025. link 43 Daunt R, Dalton K, Curtin D, O'Mahony D. Factors Influencing Hospital Physicians' Recognition of Prescribing Cascades: A Qualitative Interview Study. Drugs & aging 2025. link 44 Mouazer A, Léguillon R, Boudegzdame N, Levrard T, Le Bars Y, Simon C et al.. ABiMed: An intelligent and visual clinical decision support system for medication reviews and polypharmacy management. BMC medical informatics and decision making 2025. link 45 Stephan Y, Sutin AR, Terracciano A. Personality traits and polypharmacy: meta-analysis of five samples. Psychology & health 2025. link 46 Yu YY, Wu PH, Ho CH, Chen CJ, Liu CF, Su HC et al.. Effects of physician-led medication reconciliation on the outcomes of outpatients utilizing the PharmaCloud system. BMC health services research 2025. link 47 Lee GB, Hosking SM, Etherton-Beer C, Pasco JA, Williams LJ, Holloway-Kew KL et al.. Defining polypharmacy in older adults: a cross-sectional comparison of prevalence estimates calculated according to active ingredient and unique product counts. International journal of clinical pharmacy 2025. link 48 Thiruchelvam K, Egan N, Hasan SS, Byles J. Impact of Australian home medicines reviews on continuous polypharmacy and associated costs among older women: a cohort study. International journal of clinical pharmacy 2025. link 49 Mena S, Dubois J, Schneider M, Niquille A. Implementation of medication reviews to optimize the use of medications in Swiss nursing homes: a mixed-methods study. BMC health services research 2025. link 50 Agwunobi AJ, Seeley AE, Tucker KL, Bateman PA, Clark CE, Clegg A et al.. Understanding structured medication reviews delivered by clinical pharmacists in primary care in England: a national cross-sectional survey. BMJ open 2025. link 51 Kinahan C, Kirke C, O'Hagan L, Moriarty F, Murphy KD, Sahm LJ et al.. Evaluating the impact of general practice pharmacist-led person-centred medicines reviews on medicines appropriateness and patient-reported outcome measures. British journal of clinical pharmacology 2025. link 52 Meyer S, Söling S, Lampe D, Poppe A, Bartels R, Grandt D et al.. Implementation of an electronic medication management support system in hospitalised polypharmacy patients: study protocol of a stepped-wedge cluster-randomised controlled trial (TOP study). BMJ open 2025. link 53 Yang HW, Yu CH, Huang TY, Huang CH, Su YJ. Reducing polypharmacy through deprescribing in the emergency department. Medicine 2025. link 54 Bischof T, Al Jalali V, Zeitlinger M, Jorda A, Hana M, Singeorzan KN et al.. Chat GPT vs. Clinical Decision Support Systems in the Analysis of Drug-Drug Interactions. Clinical pharmacology and therapeutics 2025. link 55 Al Bulushi S, McIntosh T, Talkhan H, Grant A, Stewart D, Al Famy M et al.. Barriers and facilitators to implementing polypharmacy management frameworks: a theory based qualitative exploration of key stakeholders. International journal of clinical pharmacy 2025. link 56 Madanat F, Noorsaeed S, Alkhlaifat R, Mueller T, Kurdi A. A comprehensive systematic review of the types of medication classes targeted by deprescribing tools and the tools/interventions applied to each class. Expert review of clinical pharmacology 2025. link 57 Khadka A, Kaundinnyayana S, Roka K, Poudel A, Shrestha S. Exploration of Perceptions of Deprescribing Practices Among Doctors in a Low- and Middle-Income Country: A Mixed-Methods Study. Basic & clinical pharmacology & toxicology 2025. link 58 Payne RA, Blair PS, Caddick B, Chew-Graham CA, Dreischulte T, Duncan LJ et al.. Optimising polypharmacy management in primary care through general practitioner-pharmacist collaboration, informatics, and enhancing clinician engagement: the IMPPP cluster-randomised trial. The lancet. Healthy longevity 2025. link 59 Kumar A, Konduru RK, Rajaram S, Mani M, Natarajan A, Cherian JJ et al.. Implementation of an Interdepartmental Collaborative Medication Review to Reduce Potentially Inappropriate Medication Use in Hospitalized Older Adults: Protocol for a Mixed Methods Study. JMIR research protocols 2025. link 60 Socrates V, Wright DS, Huang T, Fereydooni S, Dien C, Chi L et al.. Identifying Deprescribing Opportunities With Large Language Models in Older Adults: Retrospective Cohort Study. JMIR aging 2025. link 61 Schuh MJ, Crosby SK. Polypharmacy as Formal Training and a Model of Practice. The Senior care pharmacist 2024. link 62 Gavazova E, Staynova R, Grekova-Kafalova D. Managing polypharmacy through medication review tools - pros and cons. Folia medica 2024. link 63 Zhao D, Huang P, Yu L, He Y. Pharmacokinetics-Pharmacodynamics Modeling for Evaluating Drug-Drug Interactions in Polypharmacy: Development and Challenges. Clinical pharmacokinetics 2024. link 64 Daunt R, Curtin D, O'Mahony D. Optimizing drug therapy for older adults: shifting away from problematic polypharmacy. Expert opinion on pharmacotherapy 2024. link 65 Santra G. Polypharmacy and Deprescription: Role of Internists. The Journal of the Association of Physicians of India 2024. link 66 Russ K, Vaňková T. Lékové interakce - rizika u pacientů s polypragmazií. Casopis lekaru ceskych 2024. link 67 Hartinger JM, Bobek DL. Polypragmazie a jak jí předcházet. Casopis lekaru ceskych 2024. link 68 Barakat M, Nassar R, Gharaibeh L, Thiab S, Nashwan AJ. Current Landscape and Future Directions of Deprescribing and Polypharmacy Practices in Jordan. Medical principles and practice : international journal of the Kuwait University, Health Science Centre 2024. link 69 Abeleira-Pazos MT, García-Mato E, Diniz-Freitas M, Muñoz-Navarro C, Lago-Méndez L, Vázquez-García E et al.. Discrepancy in medications reported by elderly patients in the dental office and in their electronic medical records: A pilot study. Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry 2024. link 70 Kassis A, Moles R, Carter S. Stakeholders' perspectives and experiences of the pharmacist's role in deprescribing in ambulatory care: A qualitative meta-synthesis. Research in social & administrative pharmacy : RSAP 2024. link 71 Tantipinichwong N, Keller MS. Operation Polypharmacy: a pharmacist-led ambulatory care clinic design and evaluation for older patients. Scientific reports 2024. link 72 Geremie T, Guiguet-Auclair C, Laroche ML, Mely P, Gerbaud L, Blanquet M. Deprescribing in older adults in a French community: a questionnaire study on patients' beliefs and attitudes. BMC geriatrics 2024. link 73 Agosti P, D'Avanzo B, Monti I, Cortesi L, Nobili A, Tettamanti M. Development and validation of the Medical Attitudes Towards Deprescribing Questionnaire. Internal and emergency medicine 2024. link 74 Pocknell S, Fudge N, Collins S, Roberts C, Swinglehurst D. 'Troubling' medication reviews in the context of polypharmacy and ageing: A linguistic ethnography. Social science & medicine (1982) 2024. link 75 Kim S, Lee H, Park J, Kang J, Rahmati M, Rhee SY et al.. Global and regional prevalence of polypharmacy and related factors, 1997-2022: An umbrella review. Archives of gerontology and geriatrics 2024. link 76 Lamy JB, Mouazer A, Léguillon R, Lelong R, Darmoni S, Sedki K et al.. Adaptive questionnaires for facilitating patient data entry in clinical decision support systems: methods and application to STOPP/START v2. BMC medical informatics and decision making 2024. link 77 Shin WY, Go TH, Kim JH. Trends in commonly used and potentially inappropriate medications in older Korean patients with polypharmacy. BMC geriatrics 2024. link 78 Gagnon ME, Mésidor M, Simard M, Chiu YM, Gosselin M, Candas B et al.. A comparative analysis of medication counting methods to assess polypharmacy in medico-administrative databases. Research in social & administrative pharmacy : RSAP 2024. link 79 Hogervorst S, Adriaanse MC, Vervloet M, Teichert M, Beckeringh JJ, van Dijk L et al.. A survey on the implementation of clinical medication reviews in community pharmacies within a multidisciplinary setting. BMC health services research 2024. link 80 Ghassab-Abdollahi N, Ghorbani Z, Kheirollahi N, Nadrian H, Hashemiparast M. Exploring the reasons for self-administration medication errors among illiterate and low-literate community-dwelling older adults with polypharmacy: a qualitative study. BMC geriatrics 2024. link 81 Lüthold RV, Rozsnyai Z, Weir KR, Streit S, Jungo KT. Exploring GP and patient attitudes towards the use and deprescribing of dietary supplements: a survey study in Switzerland. BMC primary care 2024. link 82 Parslow RM, Duncan LJ, Caddick B, Chew-Graham CA, Turner K, Payne RA et al.. Collaborative discussions between GPs and pharmacists to optimise patient medication: a qualitative study within a UK primary care clinical trial. The British journal of general practice : the journal of the Royal College of General Practitioners 2024. link 83 Roncal-Belzunce V, Gutiérrez-Valencia M, Leache L, Saiz LC, Bell JS, Erviti J et al.. Systematic review and meta-analysis on the effectiveness of multidisciplinary interventions to address polypharmacy in community-dwelling older adults. Ageing research reviews 2024. link 84 Koren MJ, Kelly NA, Lau JD, Jonas CK, Pinheiro LC, Banerjee S et al.. Association of Healthy Lifestyle and Incident Polypharmacy. The American journal of medicine 2024. link 85 Mortelmans L, Goossens E, De Graef M, Van Dingenen J, De Cock AM, Petrovic M et al.. Evaluation of methods measuring medication adherence in patients with polypharmacy: a longitudinal and patient perspective. European journal of clinical pharmacology 2024. link 86 Warmoth K, Rees J, Day J, Cockcroft E, Aylward A, Pollock L et al.. Assessing deprescribing tools for implementation in care homes: A qualitative study of the views of care home staff. Research in social & administrative pharmacy : RSAP 2024. link 87 Etherton-Beer C, Page A, Criddle D, Somers G, Parkinson L, Clifford R et al.. The Australian Team Approach to Polypharmacy Evaluation and Reduction (AusTAPER) hospital study: effect of a collaborative medication review on the number of current regular medicines for older hospital inpatients. Internal medicine journal 2024. link 88 Sánchez-Valle J, Correia RB, Camacho-Artacho M, Lepore R, Mattos MM, Rocha LM et al.. Prevalence and differences in the co-administration of drugs known to interact: an analysis of three distinct and large populations. BMC medicine 2024. link 89 Pereira A, Veríssimo M, Ribeiro O. Deprescribing in Older Adults: Attitudes, Awareness, Training, and Clinical Practice Among Portuguese Physicians. Acta medica portuguesa 2024. link 90 Van der Linden L, Tournoy J. Prevalence and trends in polypharmacy and excessive polypharmacy: a retrospective national database analysis (2012-2021). International journal of clinical pharmacy 2024. link 91 Mohammad AK, Hugtenburg JG, Vanhommerig JW, van den Bemt PMLA, Denig P, Karapinar-Carkıt F. Identifying and quantifying potentially problematic prescribing cascades in clinical practice: A mixed-methods study. Journal of the American Geriatrics Society 2024. link 92 Growdon ME, Hunt LJ, Miller MJ, Halim M, Karliner LS, Gonzales R et al.. eConsultation for Deprescribing Among Older Adults: Clinician Perspectives on Implementation Barriers and Facilitators. Journal of general internal medicine 2024. link 93 Brünn R, Basten J, Lemke D, Piotrowski A, Söling S, Surmann B et al.. Digital Medication Management in Polypharmacy—Findings of a Cluster-Randomized, Controlled Trial With a Stepped-Wedge Design in Primary Care Practices (AdAM). Deutsches Arzteblatt international 2024. link 94 Rao A, Kim J, Lie W, Pang M, Fuh L, Dreyer KJ et al.. Proactive Polypharmacy Management Using Large Language Models: Opportunities to Enhance Geriatric Care. Journal of medical systems 2024. link 95 Rea E, Portman D, Ioannou K, Lumley B. Pharmacist-driven deprescribing initiative in primary care. Journal of the American Pharmacists Association : JAPhA 2024. link 96 Dara ON, Ibrahim AA, Mohammed TA. Advancing medical imaging: detecting polypharmacy and adverse drug effects with Graph Convolutional Networks (GCN). BMC medical imaging 2024. link 97 Liu L, Brokenshire B, Davies D, Harrison J. Preliminary feasibility assessment of a targeted, pharmacist-led intervention for older adults with polypharmacy: a mixed-methods study. International journal of clinical pharmacy 2024. link 98 O'Mahony C, Dalton K, O'Hagan L, Murphy KD, Kinahan C, Coyle E et al.. Economic cost-benefit analysis of person-centred medicines reviews by general practice pharmacists. International journal of clinical pharmacy 2024. link 99 Dil-Nahlieli D, Ben-Yehuda A, Souroujon D, Hyam E, Shafran-Tikvah S. Validation of a novel Artificial Pharmacology Intelligence (API) system for the management of patients with polypharmacy. Research in social & administrative pharmacy : RSAP 2024. link 100 Thompson W, Lundby C, Bleik A, Waring H, Hong JA, Xi C et al.. Measuring Quality of Life in Deprescribing Trials: A Scoping Review. Drugs & aging 2024. link