Overview
Neuroblastoma is a malignant tumor that arises from primitive neural crest cells. It is the most common extracranial solid tumor of childhood.Diagnosis
Neuroblastoma can present with a variety of symptoms depending on the location of the primary tumor and presence of metastases.
Diagnostic imaging modalities include computed tomography (CT) 1.Management
Surgical therapy is a component of management 1.
Ventriculoperitoneal shunt placement is a notable procedure performed 1.Special Populations
This review focuses on pediatric patients aged 0-18 years, with the majority (66.1%) belonging to the 0-5 age range 1.
Most patients (63.4%) presented between 1-12 months of age 1.Key Recommendations
Computed tomography is a frequently utilized diagnostic imaging modality 1. (Evidence: Moderate)
Surgical therapy is utilized in the management of neuroblastoma 1. (Evidence: Moderate)
Ventriculoperitoneal shunt placement is a common surgical procedure 1. (Evidence: Moderate)References
1 Oyemolade TA, Mukumbya B, Oboh EN, Nischal SA, Ozobu I, Palla A et al.. Profile of Pediatric Neurosurgery in Nigeria from 1962 to 2021: A Systematic Review. World neurosurgery 2024. link