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Cardiology2868 papers

Sleep apnea

Last edited: 4/23/2026

Overview

Obstructive sleep apnea (OSA) is characterized by recurrent episodes of partial or complete upper airway obstruction during sleep, leading to disrupted breathing, hypoxia, and sleep fragmentation. It is associated with numerous comorbidities, including cardiovascular diseases, hypertension, and metabolic disorders 1101118202332353941445165.

Diagnosis

  • Key Diagnostic Criteria: Recurrent apnea or hypopnea events, oxygen desaturation, and sleep fragmentation 18285257.
  • Recommended Tests: Polysomnography (PSG) is the gold standard for diagnosis 1285157.
  • Grading: Severity is typically graded by the apnea-hypopnea index (AHI): mild (5-14 events/hour), moderate (15-29 events/hour), severe (≥30 events/hour) 11639.

    • Management

  • First-Line Treatments:
    • - Continuous Positive Airway Pressure (CPAP): Primary treatment for moderate to severe OSA 32394560. - Mandibular Advancement Devices (MADs): Effective for mild to moderate OSA 31.
  • Adjunctive Treatments:
    • - Lifestyle Modifications: Weight loss, positional therapy, avoiding alcohol and sedatives 11023. - Surgical Interventions: Uvulopalatopharyngoplasty (UPPP), tonsillectomy, and newer techniques like barbed suture pharyngoplasty 353340. - Pharmacological Interventions: Limited evidence; GLP-1 receptor agonists show promise in specific populations 3335.

    Special Populations

  • Pediatrics: Drug-induced sleep endoscopy (DISEDS) can guide surgical interventions effectively 2.
  • Elderly: Increased risk of adverse events during procedural sedation; careful monitoring required 5355.
  • Comorbidities: OSA management impacts cardiovascular outcomes; CPAP reduces cardiovascular morbidity 111423324165.
  • Hypertension: OSA significantly influences blood pressure control; CPAP therapy beneficial 10183265.

    • Key Recommendations

  • Use Polysomnography for Diagnosis: PSG is essential for diagnosing OSA and grading severity 15157. (Evidence: Strong)
  • Initiate CPAP for Moderate to Severe OSA: CPAP therapy is recommended as first-line treatment for moderate to severe OSA 323960. (Evidence: Strong)
  • Consider Lifestyle Modifications: Incorporate weight loss and avoidance of alcohol and sedatives to manage OSA 11023. (Evidence: Moderate)
  • Monitor High-Risk Patients During Sedation: Extra vigilance is needed for patients with OSA undergoing procedural sedation 5355. (Evidence: Moderate)
  • Evaluate Comorbid Conditions: Address cardiovascular risks and hypertension management in OSA patients through CPAP therapy 11184165. (Evidence: Moderate)

    • References

    Showing 100 most recent of 1406 indexed papers.

    1 Wei GC, Zhao Q, Chen QL, Xiao Q, Zhou GP, Wang YP et al.. Assessing the causal association between obstructive sleep apnea and the risk of atrial fibrillation. Medicine 2026. link 2 Ibrahim AF, Khan S, Hoang-Tran C, Nanu DP, Nguyen SA, Carr MM. Pediatric Drug-Induced Sleep Endoscopy Directed Surgery Outcomes With Trisomy 21 Subgroup Comparison: A Meta-Analysis. Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 2026. link 3 Marzetti A, Tripodi C, Raponi I. Tonsils Sparing Antero-Lateral Barbed Pharyngoplasty: A Minimally Invasive Approach for OSAHS. The Laryngoscope 2026. link 4 Onozawa T, Hase Y, Kimura Y, Kido K. Intravenous Sedation of a Patient With Morbid Obesity and Severe Sleep Apnea Syndrome for Dental Treatment: A Case Report. Anesthesia progress 2026. link 5 Tekumalla S, Kaki P, Lu J, Boon M, Huntley C. Downstream Impact of a Sleep Surgery Program; Optimizing Patient Care and Generating Clinical Volume. The Laryngoscope 2026. link 6 Cammaroto G, Mira FA, Favier V, Nunes HDSS, de Castro JV, Carsuzaa F et al.. Experts V/S AI´s 2.0: Comparative evaluation of AI models and expert consensus in obstructive sleep apnea assessment. European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery 2026. link 7 Rasmussen NG, Martin KA, Dunn RA, Garrett AL, Bansberg SF, Ruoff CM. Resolution of central sleep apnea following upper airway surgery: A case report. Sleep medicine 2026. link 8 Zhang X, Tang H, Han T, Li Y, Su L. The diagnostic yield of a structured comorbidity workup in a real-life outpatient population with obstructive sleep apnea: a cross-sectional study. Annals of medicine 2026. link 9 Bokov P, Dudoignon B, Delclaux C. Hypoxic burden as a cause of cardiovascular morbidity in childhood obstructive sleep apnea. Pediatric research 2026. link 10 Buffolo F, Votta S, Goi J, Burrello J, Di Dalmazi G, Cicero AFG et al.. Screening of obstructive sleep apnea in patients with hypertension: review of the literature and results of an Italian survey. Journal of hypertension 2026. link 11 Zhao W, Du J, Liu Y, Zhou Y, Zhang Z, Li S et al.. Longitudinal changes of obstructive sleep apnea and its impact on cardiovascular outcomes: Results from the Sleep Heart Health Study. Pulmonology 2026. link 12 Huhtakangas JK, Huhtakangas J, Haapea M, Saaresranta T. OSA Treatment Lowers the Risk of Declining Daily Activities. Journal of the neurological sciences 2026. link 13 Wang Z, Xu L, Lu M, Yu W. Association between obstructive sleep apnea and coronary inflammation: A coronary CT angiography study. Sleep medicine 2026. link 14 Malhotra A, More S, Alpert N, Pépin JL, Cole KV, Woodford C et al.. Dose-response relationship of sleep apnea therapy and healthcare use in patients with comorbidities. Sleep 2026. link 15 Durak B, Özol D, Saraç S, Durak İ, Tanrıkulu A. The Hidden Burden of COMISA in Hypertensive Obstructive Sleep Apnea Patients. Anatolian journal of cardiology 2026. link 16 Matthes S, Treml M, Schiza SE, Bouloukaki I, Trakada G, Pataka A et al.. The modified Baveno classification for obstructive sleep apnoea: design of a pan-European prospective study. Sleep medicine 2026. link 17 Mokhlesi B, Hache-Marliere M, Bjork ST, Jain D, Malhotra A, Masa JF et al.. Impact of positive airway pressure therapy on pulmonary arterial pressures in obstructive sleep apnoea or obesity hypoventilation syndrome: a systematic review and meta-analysis. The European respiratory journal 2026. link 18 Guo C, Dou JH, Guo FS, Li DN, Han T, Wei J. Association between hemoglobin and all-cause mortality in patients with obstructive sleep apnea and hypertension: insights from an observational study. Journal of human hypertension 2026. link 19 Yang X, Wang C, Ouyang D, Xu H, Wu Z, Ye H et al.. CDC25A Alleviates Obstructive Sleep Apnea-Hypopnea Syndrome With Hypertension and Inhibits Ferroptosis. Journal of sleep research 2026. link 20 Andersen ML, Alvarenga TA, Glauser VA, Vasco MB, Drager LF, Tufik S. Sleep apnea, heart health and testosterone: unravelling the triad of well-being. EBioMedicine 2026. link 21 Pang L, Du S, Wu S, Xian Q, Zeng Z, Guo D et al.. Genetic assessment of the causal relationship between obstructive sleep apnea and pulmonary hypertension: Mendelian randomization and meta-analysis. Respiratory medicine 2026. link 22 Wei F, Wu T, Deng J, Gong J, Zhang S, Cui Z. Development and Validation of an Explainable Machine Learning Model for Identifying Hypertension Status in Patients With Obstructive Sleep Apnea. Journal of clinical hypertension (Greenwich, Conn.) 2026. link 23 Feng T, Li Q, Chen Y, Duan R. Evaluating the relationship between obstructive sleep apnea and all-cause and cause-specific mortality in adults with and without metabolic syndrome using real-world data. European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery 2026. link 24 Imani MM, Imani A, Akbari S, Sadeghi M, Brühl AB, Brand S. A systematic review, meta-analysis, and trial sequential analysis on association of circulating vascular cell adhesion molecule-1 (VCAM-1) levels in obstructive sleep apnea adults: A possible link between cardiovascular disease and obstructive sleep apnea. International orthodontics 2026. link 25 Shahrbabaki SS, Mittinty M, Tonchev IR, Strong C, Chapman D, Lorensini S et al.. Continuous positive airway pressure reduces nocturnal arrhythmia avalanche burden in obstructive sleep apnea: An adherence-dependent effect. Heart rhythm 2026. link 26 Ueda K, Yeerbolati A, Liang L, Ogura S, Takase M, Goda N et al.. The nondipping blood pressure pattern induced by chronic intermittent hypoxia and its renal mechanism. Journal of hypertension 2026. link 27 Bock JM, Vungarala S, Sompalli S, Covassin N, Bukartyk J, Karim S et al.. High-Intensity Atorvastatin and 24-Hour Blood Pressure in Obstructive Sleep Apnea: A Randomized, -Double-Blind, Placebo-Controlled Pilot Study. American journal of hypertension 2026. link 28 Vermeer J, van den Broek M, Vinck-de Greef T, Janssen H, van Hirtum P, Overeem S et al.. Obstructive sleep apnea screening performance of the STOP-BANG questionnaire and a home sleep apnea test device in atrial fibrillation ablation candidates. Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing 2026. link 29 Nassi T, Amidi Y, Oppersma E, Donker DW, Redeker NS, Westover MB et al.. Unraveling sleep apnea dynamics: quantifying loop gain using dynamical modeling of ventilatory control. Sleep 2026. link 30 Verbraecken J, Amodio E, Basoglu OK, Bellazzi R, Bradicich M, Bruyneel M et al.. European Respiratory Society statement on advanced telemedicine for obstructive sleep apnoea (e-Sleep). The European respiratory journal 2025. link 31 Sousa S, Correia S, de Almeida AM, Videira G, Dias R, Ramos SF et al.. Treatment of obstructive sleep apnea syndrome (OSAS) with mandibular advancement devices-A statement of the Portuguese Society of Pulmonology, the Portuguese Society of Stomatology and Dental Medicine, the Portuguese Dental Association, and the Portuguese Society of Temporomandibular Disorders, Orofacial Pain and Sleep. Pulmonology 2025. link 32 Benjafield AV, Pepin JL, Cistulli PA, Wimms A, Lavergne F, Sert Kuniyoshi FH et al.. Positive airway pressure therapy and all-cause and cardiovascular mortality in people with obstructive sleep apnoea: a systematic review and meta-analysis of randomised controlled trials and confounder-adjusted, non-randomised controlled studies. The Lancet. Respiratory medicine 2025. link00002-5) 33 Kow CS, Ramachandram DS, Hasan SS, Thiruchelvam K. Efficacy and safety of GLP-1 receptor agonists in the management of obstructive sleep apnea in individuals without diabetes: A systematic review and meta-analysis of randomized, placebo-controlled trials. Sleep medicine 2025. link 34 Papageorgiou SN, Konstantinidis I, Papadopoulou AK, Apostolidou-Kiouti F, Avgerinos I, Pataka A et al.. Comparative efficacy of non-pharmacological interventions for adults with sleep apnea: A systematic review and network meta-analysis. Sleep medicine 2025. link 35 Yang R, Zhang L, Guo J, Wang N, Zhang Q, Qi Z et al.. Glucagon-like Peptide-1 receptor agonists for obstructive sleep apnea in patients with obesity and type 2 diabetes mellitus: a systematic review and meta-analysis. Journal of translational medicine 2025. link 36 Badr MS, Khayat RN, Allam JS, Hyer S, Mustafa RA, Naughton MT et al.. Treatment of central sleep apnea in adults: an American Academy of Sleep Medicine clinical practice guideline. Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine 2025. link 37 Mehra R, Auckley DH, Johnson KG, Billings ME, Carandang G, Falck-Ytter Y et al.. Evaluation and management of obstructive sleep apnea in adults hospitalized for medical care: an American Academy of Sleep Medicine clinical practice guideline. Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine 2025. link 38 Yeh WC, Li YS, Chang YP, Hsu CY. The efficacy and safety of dual orexin receptor antagonists in obstructive sleep apnea: A systematic review and meta-analysis of randomised controlled trials. Journal of sleep research 2025. link 39 Benning L, Herzig JJ, Mollet MS, Bradicich M, Pengo MF, Ulrich S et al.. Effects of CPAP on Blood Pressure Parameter Across Different Severities of Obstructive Sleep Apnoea: A Meta-Analysis. Journal of sleep research 2025. link 40 McCray LR, Kulangara AJ, Nguyen SA, Meyer TA, Labadie RF, Abdelwahab MA. Suicidality in adults with obstructive sleep apnea: A systematic review and Meta-Analysis. Sleep & breathing = Schlaf & Atmung 2025. link 41 Li SS, Tian XD, Song JK, Wu CZ, Wang WL, Tang Z. Advanced Oxidation Protein Products in Obstructive Sleep Apnea Hypopnea Syndrome-A Systematic Review and Meta-Analysis. Journal of oral rehabilitation 2025. link 42 Sajith Kumar S, Suchitra Lakshmi G, Sohail A, Jagadeesh KV, Bagepally BS. Cost effectiveness of obstructive sleep apnea therapies: a systematic review and meta-analysis of cost utility studies. Expert review of pharmacoeconomics & outcomes research 2025. link 43 Wang M, Yin X, Liang Y, Zhang C, Zhang X, Jiang X et al.. Comparative efficacy of electrical stimulation therapies for obstructive sleep apnea: A network meta-analysis of randomized controlled trials. Medicine 2025. link 44 Tahmasebi A, Beheshti R, Mahmoudi M, Jalilzadeh M, Salehi-Pourmehr H. Alterations in gut microbial community structure in obstructive sleep apnea /hypopnea syndrome (OSAHS): A systematic review and meta-analysis. Respiratory medicine 2025. link 45 Paradowska-Stolarz AM. Is malocclusion a risk factor for obstructive sleep apnea and temporomandibular disorders? An orthodontic point of view. Dental and medical problems 2025. link 46 Mertz L. Beyond the Mask: Nerve Stimulation and Other Breakthroughs for Sleep Apnea. IEEE pulse 2025. link 47 Bates M. "Not Your Grandfather's CPAP": Improving Sleep Apnea Therapy Adherence With Emerging Technology. IEEE pulse 2025. link 48 Grifantini K. Flipping the Script: How New Drugs Are Disrupting Sleep Apnea Care. IEEE pulse 2025. link 49 Andresen C, Sideris A. Industry Corner Live With Somnair CEO Anders Sideris. IEEE pulse 2025. link 50 Banks J. Transformative OSA Orthopedic Surgery: Reducing Reliance on Nightly Devices. IEEE pulse 2025. link 51 Park S, Bak SH, Kim HS, Lee KA. Association between obstructive sleep apnea and hyperuricemia/gout in the general population: a cross-sectional study. BMC musculoskeletal disorders 2025. link 52 Kashiwabara K, Tanaka F, Yamanouchi T, Yoshida M, Yoshida T, Ando M. Clinical predictors of underlying severe obstructive sleep apnea in patients undergoing gastrointestinal endoscopy under conscious sedation. Sleep & breathing = Schlaf & Atmung 2025. link 53 Ceban F, Abayomi N, Saripella A, Ariaratnam J, Katsnelson G, Yan E et al.. Adverse events in patients with obstructive sleep apnea undergoing procedural sedation in ambulatory settings: An updated systematic review and meta-analysis. Sleep medicine reviews 2025. link 54 Choi H, Lee CH, Jung YJ, Lee DC, Lee SW. Can oxygen desaturation during gastrointestinal endoscopy under conscious sedation predict obstructive sleep apnea?. Respiratory medicine 2025. link 55 Fisher JD, Aldrich T, Lewallen L, Adkins J, Mustehsan MH, Ash Y et al.. Safety of non-anesthesiologist positive pressure ventilation and sedation/analgesia during cardiac electrophysiology (EP) procedures in high-risk patients with known or risk factors for obstructive sleep apnea (OSA). Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing 2025. link 56 Gündüz Ö, Özcan KM, Kundi FCS, Erkılıç E, Fırat S. Determination of optimal sedation depth in sleep endoscopy with bispectrometry and simultaneous polysomnography. European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery 2025. link 57 Kashiwabara K, Tanaka F, Yamanouchi T, Yoshida M, Yoshida T, Ando M. Severity of obstructive sleep apnea diagnosed incidentally during gastrointestinal endoscopy under conscious sedation. Sleep & breathing = Schlaf & Atmung 2025. link 58 Li H, Jia X, Ye H, Liang JW, Zhao WL, Cui P et al.. Impact of lateral positioning on upper airway morphology in sedated children under five. World journal of pediatrics : WJP 2025. link 59 Kaffenberger TM, Huntley C, Boon M, Soose RJ, Whelan RL, Postol A et al.. Analysis of Recent Sleep Surgery Fellowship Training. The Laryngoscope 2025. link 60 Llerena P, Kaki P, DeKloe J, Kim S, Jackson J, Kaffenberger TM et al.. Comprehensive Management of Obstructive Sleep Apnea With CPAP in a Surgical Otolaryngology Practice. The Laryngoscope 2025. link 61 Ikeda K, Chiba S. Screening of pediatric obstructive sleep apnea using video monitoring. International journal of pediatric otorhinolaryngology 2025. link 62 Archontogeorgis K, Nena E, Steiropoulos P. Roles of vitamins and nutrition in obstructive sleep apnea. Expert review of respiratory medicine 2025. link 63 Inoue M, Sakata S, Arima H, Yamato I, Oishi E, Ibaraki A et al.. Sleep-related breathing disorder in a Japanese occupational population and its association with exercise-induced blood pressure elevation. Hypertension research : official journal of the Japanese Society of Hypertension 2025. link 64 Condoleo V, Severini G, Armentaro G, Francica M, Crudo G, De Marco M et al.. Effect of continuous positive airway pressure on non-fatal stroke and paroxysmal atrial fibrillation recurrence in obstructive sleep apnoea elderly patients. European journal of internal medicine 2025. link 65 Akinmoju OD, Olatunji G, Kokori E, Ogieuhi IJ, Babalola AE, Obi ES et al.. Comparative Efficacy of Continuous Positive Airway Pressure and Antihypertensive Medications in Obstructive Sleep Apnea-Related Hypertension: A Narrative Review. High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension 2025. link 66 Muniz CR, Borges TGV, Ferreira FR, Brendim MP, Muxfeldt ES. Relationship between Quality of Life and Swallowing in Hypertensive Individuals with Obstructive Sleep Apnea. Dysphagia 2025. link 67 Moscucci F, Bucciarelli V, Gallina S, Sciomer S, Mattioli AV, Maffei S et al.. Obstructive sleep apnea syndrome (OSAS) in women: A forgotten cardiovascular risk factor. Maturitas 2025. link 68 Khan AY, Curry B, Jergel A, Keesari R, Prosky J, Garcia RU. Obstructive Sleep Apnea and Short-Term Outcomes After Pediatric Cardiac Surgery. Pediatric cardiology 2025. link 69 Wang Y, Shi C, Luo J, Huang R, Xiao Y. Rapid eye movement (REM)-related obstructive sleep apnea and hypertension: insights from the clinical spectrum of apnea-hypopnea index ratios across REM and non-REM sleep stages in a Chinese cohort. Journal of sleep research 2025. link 70 Ben Hmida L, Moussa I, Jallouli NL, Mrassi H, Sahnoun I, Douik El Gharbi L. Relationship between Charlson Comorbidity Index and Obstructive Sleep Apnea severity indicators in a Tunisian cohort. La Tunisie medicale 2025. link 71 Goyal A, Pakhare A, Pavirala ST, Lahiri A, Shrivastava N, Bohra A et al.. Prevalence and association analysis of obstructive sleep apnea in India: Results from BLESS cohort. Sleep medicine 2025. link 72 Sanchez-Azofra A, Orr JE, Sanz-Rubio D, Marin-Oto M, Alarcon-Sisamon S, Vicente E et al.. Apnea-Specific Pulse-Rate Response is Associated With Early Subclinical Atherosclerosis in Obstructive Sleep Apnea. Archivos de bronconeumologia 2025. link 73 Gang C, Chen C. Age at diagnosis of obstructive sleep apnea and subsequent risk of dementia. Journal of psychiatric research 2025. link 74 Pejovic S, Shang Y, Vgontzas AN, Fernandez-Mendoza J, He F, Li Y et al.. C-reactive protein improves the ability to detect hypertension and insulin resistance in mild-to-moderate obstructive sleep apnea: Age effect. Journal of sleep research 2025. link 75 Abd-Alrazaq A, Aslam H, AlSaad R, Alsahli M, Ahmed A, Damseh R et al.. Detection of Sleep Apnea Using Wearable AI: Systematic Review and Meta-Analysis. Journal of medical Internet research 2024. link 76 Saba ES, Kim H, Huynh P, Jiang N. Orofacial Myofunctional Therapy for Obstructive Sleep Apnea: A Systematic Review and Meta-Analysis. The Laryngoscope 2024. link 77 Malhotra A, Heilmann CR, Banerjee KK, Dunn JP, Bunck MC, Bednarik J. Weight reduction and the impact on apnea-hypopnea index: A systematic meta-analysis. Sleep medicine 2024. link 78 Hasuneh MM, Toubasi AA, Khraisat B, Aldabbas H, Al-Iede M. Risk Factors of Obstructive Sleep Apnea (OSA) in Pediatric Patients: A Systematic Review and Meta-analysis. Journal of pediatric health care : official publication of National Association of Pediatric Nurse Associates & Practitioners 2024. link 79 Alrubasy WA, Abuawwad MT, Taha MJJ, Khurais M, Sayed MS, Dahik AM et al.. Hypoglossal nerve stimulation for obstructive sleep apnea in adults: An updated systematic review and meta-analysis. Respiratory medicine 2024. link 80 Lin CF, Ho NH, Hsu WL, Lin CH, Wang YH, Wang YP. Effects of aerobic exercise and resistance training on obstructive sleep apnea: a systematic review and meta-analysis. Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine 2024. link 81 Zhang J, Chen Z, Deng Y, Teng X, Ling X, He C et al.. Impacts of renal denervation on blood pressure in patients with obstructive sleep apnea. Sleep & breathing = Schlaf & Atmung 2024. link 82 Liao J, Shi Y, Gao X, Zhang B, Li Y, Xu W et al.. Efficacy of Oral Appliance for Mild, Moderate, and Severe Obstructive Sleep Apnea: A Meta-analysis. Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 2024. link 83 Gerdung CA, Ofosu DB, Rodriguez-Lopez S, Palkowski S, Keto-Lambert D, Lin M et al.. Positive Airway Pressure and Metabolic Markers in Children With Obstructive Sleep Apnea. Respiratory care 2024. link 84 Machado CAO, de Resende CMBM, Stuginski-Barbosa J, Porporatti AL, Carra MC, Michelloti A et al.. Association between obstructive sleep apnea and temporomandibular disorders: A meta-analysis. Journal of oral rehabilitation 2024. link 85 Quinlan CM, Chang X, March M, Mentch FD, Qu HQ, Liu Y et al.. Identification of novel loci in obstructive sleep apnea in European American and African American children. Sleep 2024. link 86 Zhao DF, Zhang YZ, Sun X, Su CY, Zhang LQ. Association between obstructive sleep apnea severity and depression risk: a systematic review and dose-response meta-analysis. Sleep & breathing = Schlaf & Atmung 2024. link 87 Boppana TK, Mittal S, Madan K, Tiwari P, Mohan A, Hadda V. Antioxidant therapies for obstructive sleep apnea: A systematic review and meta-analysis. Sleep & breathing = Schlaf & Atmung 2024. link 88 Prechaporn W, Hantrakul P, Ngamjarus C, Sukeepaisarnjaroen W, Sawanyawisuth K, Khamsai S. Pooled prevalences of obstructive sleep apnea and heart failure: a systematic review and meta-analysis. Heart failure reviews 2024. link 89 Zhang Y, Leng S, Hu Q, Li Y, Wei Y, Lu Y et al.. Pharmacological interventions for pediatric obstructive sleep apnea (OSA): Network meta-analysis. Sleep medicine 2024. link 90 Nobre ML, Sarmento ACA, de Oliveira PF, Wanderley FF, Diniz Júnior J, Gonçalves AK. Pharmacological treatment for obstructive sleep apnea: A systematic review and meta-analysis. Clinics (Sao Paulo, Brazil) 2024. link 91 Bulloch G, Seth I, Zhu Z, Sukumar S, McNab A. Ocular manifestations of obstructive sleep apnea: a systematic review and meta-analysis. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 2024. link 92 Zeng J, He J, Chen M, Li J. Association between mean platelet volume and obstructive sleep apnea-hypopnea syndrome: A systemic review and meta-analysis. PloS one 2024. link 93 Kim DH, Kim SW, Han JS, Kim GJ, Basurrah MA, Hwang SH. Hypoglossal Nerve Stimulation Effects on Obstructive Sleep Apnea Over Time: A Systematic Review and Meta-analysis. Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 2024. link 94 Chan YH, Teo CB, Tay JK, Cheong CS. The association between obstructive sleep apnea and osteoporosis: A systematic review and meta-analysis. Sleep medicine reviews 2024. link 95 Belanche Monterde A, Zubizarreta-Macho Á, Lobo Galindo AB, Albaladejo Martínez A, Montiel-Company JM. Mandibular advancement devices decrease systolic pressure during the day and night in patients with obstructive sleep apnea: A systematic review and meta-analysis. Sleep & breathing = Schlaf & Atmung 2024. link 96 Barateau L, Baillieul S, Andrejak C, Bequignon É, Boutouyrie P, Dauvilliers Y et al.. Guidelines for the assessment and management of residual sleepiness in obstructive apnea-hypopnea syndrome: Endorsed by the French Sleep Research and Medicine Society (SFRMS) and the French Speaking Society of Respiratory Diseases (SPLF). Respiratory medicine and research 2024. link 97 Behnoush AH, Khalaji A, Amirkhani N, Pezeshki PS. Diagnostic Role of Circulating Endocan Levels in Obstructive Sleep Apnea: A Systematic Review and Meta-Analysis. Angiology 2024. link 98 Msaad S, Khemakhem R, Abdelmouleh D. Predictive factors of persistent/recurrent pediatric obstructive sleep apnea-hypopnea syndrome after adenotonsillectomy. La Tunisie medicale 2024. link 99 Günther S, Renaud B. In patients with OSA and CVD, CPAP did not reduce major adverse cardiac and cerebrovascular events. Annals of internal medicine 2024. link 100 Farid S, Giunio-Zorkin M, Schust DJ, Cortese R. Obstructive sleep apnea in pregnancy: A review of the literature from the obstetrics practitioner's view and a proposed clinical approach. European journal of obstetrics, gynecology, and reproductive biology 2024. link

    Original source

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      Assessing the causal association between obstructive sleep apnea and the risk of atrial fibrillation. — Wei GC, Zhao Q, Chen QL, Xiao Q, Zhou GP, Wang YP et al. Medicine (2026)
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      Pediatric Drug-Induced Sleep Endoscopy Directed Surgery Outcomes With Trisomy 21 Subgroup Comparison: A Meta-Analysis. — Ibrahim AF, Khan S, Hoang-Tran C, Nanu DP, Nguyen SA, Carr MM Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery (2026)
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      Tonsils Sparing Antero-Lateral Barbed Pharyngoplasty: A Minimally Invasive Approach for OSAHS. — Marzetti A, Tripodi C, Raponi I The Laryngoscope (2026)
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      Intravenous Sedation of a Patient With Morbid Obesity and Severe Sleep Apnea Syndrome for Dental Treatment: A Case Report. — Onozawa T, Hase Y, Kimura Y, Kido K Anesthesia progress (2026)
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      Downstream Impact of a Sleep Surgery Program; Optimizing Patient Care and Generating Clinical Volume. — Tekumalla S, Kaki P, Lu J, Boon M, Huntley C The Laryngoscope (2026)
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      Experts V/S AI´s 2.0: Comparative evaluation of AI models and expert consensus in obstructive sleep apnea assessment. — Cammaroto G, Mira FA, Favier V, Nunes HDSS, de Castro JV, Carsuzaa F et al. European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery (2026)
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      The diagnostic yield of a structured comorbidity workup in a real-life outpatient population with obstructive sleep apnea: a cross-sectional study. — Zhang X, Tang H, Han T, Li Y, Su L Annals of medicine (2026)
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      Hypoxic burden as a cause of cardiovascular morbidity in childhood obstructive sleep apnea. — Bokov P, Dudoignon B, Delclaux C Pediatric research (2026)
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      Screening of obstructive sleep apnea in patients with hypertension: review of the literature and results of an Italian survey. — Buffolo F, Votta S, Goi J, Burrello J, Di Dalmazi G, Cicero AFG et al. Journal of hypertension (2026)
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      Longitudinal changes of obstructive sleep apnea and its impact on cardiovascular outcomes: Results from the Sleep Heart Health Study. — Zhao W, Du J, Liu Y, Zhou Y, Zhang Z, Li S et al. Pulmonology (2026)
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      Association between obstructive sleep apnea and coronary inflammation: A coronary CT angiography study. — Wang Z, Xu L, Lu M, Yu W Sleep medicine (2026)
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      The Hidden Burden of COMISA in Hypertensive Obstructive Sleep Apnea Patients. — Durak B, Özol D, Saraç S, Durak İ, Tanrıkulu A Anatolian journal of cardiology (2026)
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      The modified Baveno classification for obstructive sleep apnoea: design of a pan-European prospective study. — Matthes S, Treml M, Schiza SE, Bouloukaki I, Trakada G, Pataka A et al. Sleep medicine (2026)
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      Impact of positive airway pressure therapy on pulmonary arterial pressures in obstructive sleep apnoea or obesity hypoventilation syndrome: a systematic review and meta-analysis. — Mokhlesi B, Hache-Marliere M, Bjork ST, Jain D, Malhotra A, Masa JF et al. The European respiratory journal (2026)
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