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Pediatrics10 papers

Uncomplicated non-allergic asthma

Last edited: 4/10/2026

Overview

Asthma is a common chronic respiratory disease characterized by reversible airway obstruction and inflammation 1. Acute asthma exacerbations are a frequent cause of pediatric hospitalizations 1.

Diagnosis

  • No specific diagnostic criteria or grading systems are mentioned in the provided abstracts.
  • Management

  • Non-invasive positive pressure ventilation (NPPV) is being investigated as an add-on therapy to usual care (bronchodilators and corticosteroids) for acute asthma in children 1.
  • Evidence supporting the routine use of NPPV is weak, and clinical guidelines do not currently recommend it 1.
  • A previous review did not demonstrate a clear benefit of NPPV, but was limited by small sample sizes 1.
  • Special Populations

  • Pediatrics: NPPV is being assessed as an add-on therapy for children (< 18 years) hospitalized with acute asthma exacerbations 1.
  • Key Recommendations

  • Non-invasive positive pressure ventilation (NPPV) may be an effective way to improve outcomes for some children with acute asthma, although evidence is weak 1. (Evidence: Weak)
  • References

    1 Korang SK, Baker M, Feinberg J, Newth CJ, Khemani RG, Jakobsen JC. Non-invasive positive pressure ventilation for acute asthma in children. The Cochrane database of systematic reviews 2024. link

    Original source

    1. [1]
      Non-invasive positive pressure ventilation for acute asthma in children.Korang SK, Baker M, Feinberg J, Newth CJ, Khemani RG, Jakobsen JC The Cochrane database of systematic reviews (2024)

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