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Aneurysmal bone cyst

Last edited: 4/15/2026

Overview

Aneurysmal bone cysts (ABCs) are benign, blood-filled lesions characterized by multilocular cysts with thin, fibrous walls, often found in the metaphysis of long bones but can occur in any bone 3.

Diagnosis

  • Histologic confirmation: Typically achieved through surgical biopsy 1.
  • Imaging: CT and MRI are crucial for delineating cyst characteristics and guiding treatment 1.
  • Contrast studies: Utilized to assess cyst septation and avoid venous opacification during injection 1.
  • Management

  • First-line treatment: Direct fibrosing agent injection (e.g., Ethibloc) under CT guidance 1.
  • Injection technique: Requires general anesthesia, precise needle placement (14-16 gauge), and obliteration of intraosseous needle tracks with histoacryl 1.
  • Adjunctive treatments: Surgical excision may be necessary for complications like fistulization or recurrence 1.
  • Special Populations

  • Pediatrics: Direct fibrosing agent injection is used but carries risks such as pulmonary embolism and early aseptic fistulization 1.
  • Rarity in specific locations: ABCs of the patella are exceptionally rare, with limited case reports 2.
  • Key Recommendations

  • Use direct fibrosing agent injection under CT guidance for treatment, particularly in pediatric patients, with careful monitoring for complications like pulmonary embolism and fistulization (Evidence: Moderate 1).
  • Ensure meticulous technique including contrast verification and needle track obliteration to minimize complications (Evidence: Moderate 1).
  • Consider surgical excision for cases complicated by fistulization or treatment failure (Evidence: Expert opinion 1).
  • References

    1 Topouchian V, Mazda K, Hamze B, Laredo JD, Penneçot GF. Aneurysmal bone cysts in children: complications of fibrosing agent injection. Radiology 2004. link 2 Mapelli S, Giraldi A. Aneurysmal bone cyst of the patella. Italian journal of orthopaedics and traumatology 1984. link 3 Chari PR, Reddy CR. Aneurysmal bone cysts. The Australian and New Zealand journal of surgery 1976. link

    Original source

    1. [1]
      Aneurysmal bone cysts in children: complications of fibrosing agent injection.Topouchian V, Mazda K, Hamze B, Laredo JD, Penneçot GF Radiology (2004)
    2. [2]
      Aneurysmal bone cyst of the patella.Mapelli S, Giraldi A Italian journal of orthopaedics and traumatology (1984)
    3. [3]
      Aneurysmal bone cysts.Chari PR, Reddy CR The Australian and New Zealand journal of surgery (1976)

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