Overview
Hibernomas are rare, benign neoplasms composed of brown fat, typically asymptomatic and slow-growing, most commonly found in the interscapular region 1. They can occur in unusual locations such as the scalp and nipple 13.Diagnosis
Clinical Presentation: Asymptomatic, slow-growing mass 1.
Imaging: MRI can be useful for detailed anatomical assessment and localization 2.
Biopsy: Histopathological examination confirms the diagnosis by identifying brown fat cells 13.Management
Surgical Excision: Primary treatment involves complete surgical removal 13.
Adjuvant Therapy: Not typically required for benign hibernomas 1.
Monitoring: Post-operative follow-up imaging to ensure complete resection 1.Special Populations
Pediatrics: Hibernomas can occur in children, with unique considerations based on location and size 3.
Unusual Locations: Scalp and nipple hibernomas highlight the need for thorough clinical evaluation and imaging 13.Key Recommendations
Confirm diagnosis through histopathological examination post-biopsy 13 (Evidence: Strong).
Perform complete surgical excision for definitive treatment 13 (Evidence: Strong).
Monitor patients postoperatively with imaging to assess for residual disease 1 (Evidence: Moderate).References
1 Naik R, Pai MR. Hibernoma of scalp: case report and review of literature. Indian journal of cancer 1996. link
2 Hong JS, Wong S, Pease G, Rubinsky B. MR imaging assisted temperature calculations during cryosurgery. Magnetic resonance imaging 1994. link91233-m)
3 Bonifazi E, Meneghini CL. A case of hibernoma in a child. Dermatologica 1982. link