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Nephrology1 paper

Monomorphic adenoma

Last edited: 4/16/2026

Overview

Monomorphic adenoma is a benign epithelial neoplasm commonly found in the salivary glands, rarely occurring in oral mucosal sites such as the palate. 1

Diagnosis

  • Histological confirmation required for diagnosis.
  • Imaging (e.g., CT, MRI) may be used to assess extent and local invasion.
  • Fine-needle aspiration biopsy can be diagnostic but definitive diagnosis relies on histopathology. 1
  • Management

  • Surgical excision is the primary treatment modality.
  • Careful perioperative management is crucial, especially in patients with comorbidities like hemodialysis dependence.
  • Antibiotic prophylaxis may be necessary to prevent infection, though specific drug classes and doses are not detailed in the abstract. 1
  • Special Populations

  • Hemodialysis Patients: Requires meticulous management of anemia, hyperkalemia, bleeding risk, and delayed wound healing. Close monitoring and multidisciplinary care are essential. 1
  • Key Recommendations

  • Perform histological examination for definitive diagnosis of monomorphic adenoma. (Evidence: Moderate) 1
  • Employ surgical excision as the first-line treatment approach. (Evidence: Expert opinion) 1
  • In patients with comorbidities like hemodialysis, tailor perioperative care to address specific risks such as bleeding tendency and infection prophylaxis. (Evidence: Expert opinion) 1
  • References

    1 Shibata H, Ikemura K, Miyake M. Oral surgery and hemodialysis. International journal of oral surgery 1984. link80053-8)

    Original source

    1. [1]
      Oral surgery and hemodialysis.Shibata H, Ikemura K, Miyake M International journal of oral surgery (1984)

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