Overview
Subacute invasive pulmonary aspergillosis (IPA) is a complication that can occur in critically ill patients, particularly those with influenza 1. It is associated with increased morbidity and mortality 1.Diagnosis
Influenza-associated pulmonary aspergillosis (IAPA) prevalence in critically ill influenza patients is approximately 19.2% 1.
Risk factors include prior organ transplantation 1.
Clinical features and diagnostic criteria are not detailed in the provided abstract.
No grading of diagnostic certainty is mentioned.Management
Early diagnosis and initiation of antifungal treatment are essential 1.
Specific antifungal agents, doses, or treatment durations are not mentioned.Special Populations
Patients who have undergone organ transplantation are identified as a risk factor 1.Key Recommendations
Early diagnosis of IAPA and initiation of antifungal treatment are essential 1. (Evidence: Moderate)
Future research should focus on developing a clinical algorithm for IAPA 1. (Evidence: Expert opinion)References
1 Lu LY, Lee HM, Burke A, Li Bassi G, Torres A, Fraser JF et al.. Prevalence, Risk Factors, Clinical Features, and Outcome of Influenza-Associated Pulmonary Aspergillosis in Critically Ill Patients: A Systematic Review and Meta-Analysis. Chest 2024. link