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Dermatology17 papers

Folliculitis cruris pustulosa atrophicans

Last edited: 4/10/2026

Overview

Folliculitis cruris pustulosa atrophicans is a condition characterized by pustules on the legs that can lead to atrophic scarring. Atrophic scarring, in general, is considered a therapeutic challenge 13.

Diagnosis

Management

  • Microneedling (MN) is an effective therapeutic modality for atrophic acne scars, either as monotherapy or in combination with other treatments 3.
  • Combination therapy of microneedling with plasma gel (topical or intradermal injection) showed significantly greater reduction in atrophic acne scar scores compared to microneedling monotherapy 1.
  • Microneedling treatment demonstrated no serious adverse effects 3.
  • Special Populations

    Key Recommendations

  • Microneedling is an effective and well-tolerated therapeutic modality for treating atrophic acne scars 3. (Evidence: Moderate)
  • Combining microneedling with plasma gel (topical or intradermal) is more effective than microneedling monotherapy for treating atrophic acne scars 1. (Evidence: Moderate)
  • Further research is needed to validate the efficacy of microneedling with larger sample sizes and longer follow-up periods 3. (Evidence: Expert opinion)
  • References

    1 Mohamed MM, Sabry HH, Salem RM. Treatment of atrophic acne scars: Topical or intralesional plasma gel?. Photodermatology, photoimmunology & photomedicine 2022. link 2 Obeid G, Do G, Kirby L, Hughes C, Sbidian E, Le Cleach L. Interventions for chronic palmoplantar pustulosis: abridged Cochrane systematic review and GRADE assessments. The British journal of dermatology 2021. link 3 Sitohang IBS, Sirait SAP, Suryanegara J. Microneedling in the treatment of atrophic scars: A systematic review of randomised controlled trials. International wound journal 2021. link

    Original source

    1. [1]
      Treatment of atrophic acne scars: Topical or intralesional plasma gel?Mohamed MM, Sabry HH, Salem RM Photodermatology, photoimmunology & photomedicine (2022)
    2. [2]
      Interventions for chronic palmoplantar pustulosis: abridged Cochrane systematic review and GRADE assessments.Obeid G, Do G, Kirby L, Hughes C, Sbidian E, Le Cleach L The British journal of dermatology (2021)
    3. [3]
      Microneedling in the treatment of atrophic scars: A systematic review of randomised controlled trials.Sitohang IBS, Sirait SAP, Suryanegara J International wound journal (2021)
    4. [4]
      Infantile acropustulosis.McFadden N, Falk ES Cutis (1985)

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