Overview
Chronic neutrophilia is a persistent elevation of neutrophil counts in the blood. This condition can be associated with various underlying causes, including infections, inflammatory conditions, and hematologic malignancies.Diagnosis
Diagnosis is based on repeated complete blood counts demonstrating an elevated absolute neutrophil count.
Further investigation is guided by clinical suspicion and may include inflammatory markers, infectious workup, and peripheral blood smear review.Management
Management focuses on identifying and treating the underlying cause of chronic neutrophilia.
For asymptomatic individuals with benign causes, observation may be sufficient.
For symptomatic patients or those with serious underlying conditions, specific treatments targeting the etiology are required.Special Populations
Pediatric patients may require age-specific evaluation and management strategies.Key Recommendations
Adherence to prophylaxis in hemophilia patients is influenced by acceptance and self-management skills 1.
Learning self-infusion in hemophilia is typically initiated before puberty, with full self-management achieved approximately 10 years later 1.
Adherence levels to prophylaxis in hemophilia vary by age, with the highest levels in children (1-12 years) and the lowest in adults aged 25-40 years 1.References
1 Schrijvers LH, Schuurmans MJ, Fischer K. Promoting self-management and adherence during prophylaxis: evidence-based recommendations for haemophilia professionals. Haemophilia : the official journal of the World Federation of Hemophilia 2016. link