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Neurology4064 papers

Disorder of brain

Last edited: 4/23/2026

Overview

Transient ischemic attack (TIA) is a neurological event characterized by temporary symptoms due to focal brain ischemia without infarction, typically lasting less than 24 hours. It serves as a critical warning sign for impending stroke and requires urgent evaluation and management to prevent further vascular events 12921.

Diagnosis

  • Clinical Criteria: Sudden onset of focal neurological symptoms lasting less than 24 hours with complete resolution 921.
  • Recommended Tests:
  • - Neuroimaging: Diffusion-weighted imaging (DWI) to rule out infarction 1033. - Cervical Vascular Ultrasound: To identify large arterial lesions in the neck 26. - Cardiac Evaluation: To assess for potential embolic sources 21.
  • Risk Stratification Tools:
  • - ABCD2 Score: Used to quantify stroke risk within 48 hours 721. - ABCD2 Methods: Further refined risk stratification in high-risk TIA patients 5.

    Management

  • First-Line Treatments:
  • - Antiplatelet Therapy: Aspirin (typically 325 mg initially, followed by 75-100 mg daily) 121. - Secondary Prevention: Early initiation of secondary prevention strategies to reduce stroke risk 2131.
  • Adjunctive Treatments:
  • - Statins: To manage lipid levels, e.g., atorvastatin 31. - Clopidogrel: Considered in combination with aspirin for high-risk patients 31. - Endovascular Therapy: For acute vertebrobasilar occlusion, particularly within 24 hours 2538.

    Special Populations

  • Pediatrics: Rare, but TIA can occur; neuroimaging essential for diagnosis 30.
  • Elderly: Higher risk of recurrent events and comorbidities; comprehensive risk factor management crucial 22.
  • Comorbidities: Management tailored to address specific comorbidities affecting stroke risk, such as hypertension, diabetes, and hyperhomocysteinemia 56.
  • Key Recommendations

  • Urgent Evaluation and Management: Initiate urgent evaluation and management within hours of symptom onset to prevent stroke 921 (Evidence: Strong).
  • Use of ABCD2 Score: Utilize the ABCD2 score for risk stratification in TIA patients to guide immediate and short-term management 75 (Evidence: Strong).
  • Early Antiplatelet Therapy: Start aspirin therapy promptly after diagnosis to reduce stroke risk 121 (Evidence: Strong).
  • Comprehensive Secondary Prevention: Implement comprehensive secondary prevention strategies including statins and lifestyle modifications 2131 (Evidence: Moderate).
  • Endovascular Therapy Consideration: Consider endovascular therapy within 24 hours for acute vertebrobasilar occlusion 2538 (Evidence: Moderate).
  • References

    Showing 100 most recent of 1078 indexed papers.

    1 Kazal F, Ndayishimye T, Kurtzman JT. Global Perspectives on Urologic Training in Low- and Middle-income Countries. Current urology reports 2026. link 2 McLeod G, McKendrick M, Portelli R, Husz Z, James G, Hewson D et al.. Thoracic epidural insertion using extended reality hologram assistance: a randomised trial of regional anaesthesia skill performance on the soft embalmed Thiel cadaver. British journal of anaesthesia 2026. link 3 Neumann I, Afshari A, Sudy R, Van de Velde M, Debouche S, Harlet P et al.. Methodology series of ESAIC guidelines: standards in guidelines production. European journal of anaesthesiology 2026. link 4 Walton L, Flynn A, Preston E, Davey R, Freene N. Understanding implementation outcomes of cardiovascular rehabilitation for transient ischaemic attack and mild stroke: a process evaluation. European journal of cardiovascular nursing 2026. link 5 Daghlas I, Caunca MR, Kim AS. Observed Versus Predicted Stroke Risk After Transient Ischemic Attack: A Post Hoc Analysis of a Randomized Clinical Trial. Journal of the American Heart Association 2026. link 6 Pan S, Cao YZ, Lv PH, Ding Y, Liu Z, Sun W et al.. Nomogram Model for Predicting 90-Day Excellent Outcome in Patients With Acute Vertebrobasilar Artery Occlusion Undergoing Endovascular Thrombectomy. Journal of the American Heart Association 2026. link 7 Lumia S, Iobst W, Khan Z, Sokolosky S, Hutchison BT, Guzik A et al.. Performance of the ABCD2 Score in a US Emergency Department Observation Unit. Critical pathways in cardiology 2026. link 8 Roesen P, Temuulen U, Rios AS, Ganeshan R, Braemswig TB, Khalil A et al.. Baseline Cerebral Small Vessel Disease Predicting Long-Term Cognitive Decline in Transient Ischemic Attack Patients. European journal of neurology 2026. link 9 Zhang N, Guo J, Liu W, Wu J, Jiang N. Prevalence and incidence of transient ischaemic attack: a systematic review and meta-analysis. BMC neurology 2026. link 10 Fu Y, Shang T, Wang P, Peng C. Diagnostic value of 3D arterial spin labeling plus diffusion-weighted imaging for transient ischemic attack and short-term stroke prognosis: A retrospective cohort study. Medicine 2026. link 11 Rath T, Sugden M, Evans E, Dana K, Rentschler M, Bolch C et al.. The effect of surgical field suction flow rate and venous reservoir levels on gaseous microemboli transmission⋆. The journal of extra-corporeal technology 2026. link 12 McColl AJ, Luengo-Fernandez R, Vaughan-Fowler ER, Downer MB, Pendlebury ST, Binney LE et al.. Prevalence, Predictors, and Prognosis of Depression After Transient Ischemic Attack: A Population-Based Study. Stroke 2026. link 13 Takalo E, Karpala M, An X, Cobb B, Zhao S, Bari R et al.. Intrathecal dexmedetomidine for cesarean delivery and postoperative outcomes: a single-center retrospective cohort study (2019-2020). International journal of obstetric anesthesia 2026. link 14 Spiess BD. Vasoplegia and cardiopulmonary bypass: role of oxidation-reduction dysregulation as a mechanism and therapeutic target. British journal of anaesthesia 2026. link 15 Kamijo E, Nakamura A, Ishiguro T, Kawashima A. Superficial temporal artery-middle cerebral artery double bypass for vertebrobasilar insufficiency due to multivessel intracranial stenosis: A report of two cases with a network-based hemodynamic concept. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2026. link 16 Vicente F, Anastácio L, Monteiro A, Brito J, Ramalho R, Pereira P. Effectiveness of a Nutrition Education Programme on Nutritional Knowledge in Young Football Players: A Pilot Study. Nutrients 2025. link 17 Binyamin Y, Davidor N, Orbach-Zinger S, Hayuni T, Nisky I. Novel bimanual haptic simulator for epidural loss-of-resistance detection: a pilot study assessing movement strategies and performance across anesthesiologist experience levels. International journal of obstetric anesthesia 2025. link 18 Tikeshwari, Shrivas K, Tandey K, Sharma A, Chandrawanshi NK, Ghosh KK. Advances and challenges in sample preparation and analytical methods for water-soluble vitamins: Application in food, clinical, pharmaceutical samples. Journal of pharmaceutical and biomedical analysis 2025. link 19 Shi B, Wang H, Zhao L, Cheng KW. Identification and evaluation of heat-stable vitamins for simultaneous suppression of AGE content and enhancement of nutritional and functional properties. Food chemistry 2025. link 20 Alshehri AA, Alqahtani S, Aldajani R, Alsharabi B, Alzahrani W, Alguthami G et al.. Knowledge, Attitudes, and Practices of Dietary Supplement Use in Western Saudi Arabia: A Cross-Sectional Study. Nutrients 2025. link 21 Al-Sabbagh MQ, Thirunavukkarasu S, Eswaradass P. Advances in Cardiac Workup for Transient Ischemic Attack: Improving Diagnostic Yield and Reducing Recurrent Stroke Risk. Cardiology in review 2025. link 22 Ebbesen BH, Grøntved S, Modrau B, Rathleff MS, Andreasen J, Johnsen SP. Sick leave and homecare need in patients with transient ischaemic attack compared with ischaemic stroke: A nationwide follow-up study. European journal of neurology 2025. link 23 Bajrami A, Senadim S, Geyik S. A comatose vertebrobasilar occlusion patient recovering with bilateral hearing loss following full recanalization with mechanical thrombectomy. The neuroradiology journal 2025. link 24 Wang J, Zheng H, Hu F. Unilateral Carotid Rete Mirabile Presenting with Limb-Shaking Transient Ischemic Attack. World neurosurgery 2025. link 25 Xu Y, Zhang P, Hu M, Sun W, Xu G, Dai C. Vertebrobasilar Artery Occlusion Treatment Outcomes Within 24 hours of Estimated Occlusion Time. Neurosurgery 2025. link 26 Zhang J, Li J, Ding Y. Diagnostic value of cervical vascular ultrasound in large arterial lesions of the neck in patients with transient ischemic attack. The International journal of neuroscience 2025. link 27 Kalyuzhnaya YN, Logvinov AK, Pashkevich SG, Golubova NV, Seryogina ES, Potapova EV et al.. An Alternative Photothrombotic Model of Transient Ischemic Attack. Translational stroke research 2025. link 28 Sampaio Rocha-Filho PA, de Oliveira FAA. Headache attributed to transient ischemic attack: Assessment of its characteristics, associated factors and considerations on the diagnostic criteria. Journal of the neurological sciences 2025. link 29 Ebbesen BH, Modrau B, Rathleff MS, Johnsen SP, Andreasen J. 'There are things I have learned the hard way' Patient experiences on lasting challenges 4 months after Transient Ischemic Attack: A qualitative study. Journal of clinical nursing 2025. link 30 Gazeteci Tekin H, Öztekin Ö. Transient Ischemic Attack (TIA) presenting with isolated anomic aphasia due to ischemia in the posterior cingulate gyrus in a 11-year-old girl. The International journal of neuroscience 2025. link 31 Bian M, Zhong F, Wan J. Effect of atorvastatin calcium plus clopidogrel in the treatment of patients with transient ischemic attacks and its effect on blood lipids and platelets. The International journal of neuroscience 2025. link 32 Guamán-Pilco D, Chocano E, Palà E, Lamana-Vallverdú M, Penalba A, García-Rodríguez P et al.. H-FABP as a Biomarker in Transient Ischemic Attack. Journal of cardiovascular translational research 2025. link 33 Ornello R, Foschi M, De Santis F, Romoli M, Tassinari T, Saia V et al.. Transient brain ischemic symptoms and the presence of ischemic lesions at neuroimaging: Results from the READAPT study. International journal of stroke : official journal of the International Stroke Society 2025. link 34 Beishon L, Elliott AR, Mistri AK, Eveson D, Minhas JS, Quinn TJ et al.. Prevalence of Frailty in the Transient Ischaemic Attack Clinic and Its Associations with Mortality. Cerebrovascular diseases (Basel, Switzerland) 2025. link 35 Shaw L, Isaac J, Scott J, Sharp L, Smyth E, Stuart L et al.. Development of a Standardised stroke risk assessment for patients with MigraAinous symptoms Reviewed as suspected TIA (SMART): study protocol for a mixed methods study. BMJ open 2025. link 36 Purroy F, Gallego Y, Gil-Villar MP, Begue R, Arque G, Quilez A et al.. Short- and Long-Term Prognoses After Tissue-Negative Transient Ischemic Attack. Stroke 2025. link 37 White TG, Bram R, Turpin J, Shah KA, Koul P, Link T et al.. Hemodynamic outcomes of stenting for vertebrobasilar insufficiency in patients with a low flow state. Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences 2025. link 38 Nogueira RG, Jovin TG, Liu X, Hu W, Langezaal LCM, Li C et al.. Endovascular therapy for acute vertebrobasilar occlusion (VERITAS): a systematic review and individual patient data meta-analysis. Lancet (London, England) 2025. link01820-8) 39 Long B, Marcolini E, Gottlieb M. Emergency medicine updates: Transient ischemic attack. The American journal of emergency medicine 2024. link 40 Madhusoodanan V, Bitran J, Towe M, Ritch C. Financial and Business Literacy Among Urology Residents: Is this a Problem and How Can We Better Prepare Residents for their Careers?. Current urology reports 2024. link 41 Han DS, Badalato GM, Murano TE, Anderson CB. Resident Remediation: A National Survey of Urology Program Directors. Journal of surgical education 2024. link 42 Chinn GA, Gray AT, Larson MD. Overcoming Obstacles: The Legacy of Fidel Pagés, Founder of the Epidural, 100 Years After His Passing. Anesthesia and analgesia 2024. link 43 Huang Z, Mashour GA, Hudetz AG. Propofol disrupts the functional core-matrix architecture of the thalamus in humans. Nature communications 2024. link 44 Zheng D, Yu GL, Zhou YP, Zhang QM, Wang CG, Zhang S. Association between lactic acidosis and multiple organ dysfunction syndrome after cardiopulmonary bypass. PeerJ 2024. link 45 Koeder C, Perez-Cueto FJA. Vegan nutrition: a preliminary guide for health professionals. Critical reviews in food science and nutrition 2024. link 46 Kathi S, Laza H, Singh S, Thompson L, Li W, Simpson C. Simultaneous biofortification of vitamin C and mineral nutrients in arugula microgreens. Food chemistry 2024. link 47 Puścion-Jakubik A, Zimnoch KM, Socha K. Food Supplements Containing Iron-Comparison of Actual Content with Declared Content and Health Consequences. Molecules (Basel, Switzerland) 2024. link 48 Qi YP, Crider KS, Williams AM, Tripp K, Mapango C, Rhodes EC et al.. Folate and vitamin B. Birth defects research 2024. link 49 Pellowski D, Kusch P, Henning T, Kochlik B, Maares M, Schmiedeskamp A et al.. Postprandial Micronutrient Variability and Bioavailability: An Interventional Meal Study in Young vs. Old Participants. Nutrients 2024. link 50 Tanaka K, Coutts SB, Joundi RA, Singh N, Uehara T, Ohara T et al.. Presenting Symptoms and Diffusion-Weighted MRI Positivity by Time After Transient Neurologic Events: A Pooled Analysis of 3 Cohort Studies. Neurology 2024. link 51 Bager JE, Jood K, Nordanstig A, Andersson T, Nåtman J, Hjerpe P et al.. Long-term risk-factor control and secondary prevention are insufficient after first TIA: Results from QregPV. European stroke journal 2024. link 52 Algattas H, Mitha R, Agarwal N, Lang MJ. Bow Hunter Syndrome: An Illustrative Case and Operative Management. World neurosurgery 2024. link 53 Warach S, Schellinger PD. Distinguishing Transient Cerebral Ischemia From Other Brief Neurologic Events. Neurology 2024. link 54 Miyamoto S, Hayakawa M, Okune S, Shintoku R, Yamano A, Hiramine T et al.. Hidden Bow Hunter's Syndrome Diagnosed Using Dynamic Cerebral Angiography and Successfully Treated with Spinal Surgery: A Case Report and Review of the Literature. Internal medicine (Tokyo, Japan) 2024. link 55 Förster A, Ramos A, Wenz H, Groden C, Alonso A. Computed diffusion-weighted imaging in patients with transient neurovascular symptoms with and without ischemic infarction. Journal of neuroradiology = Journal de neuroradiologie 2024. link 56 Wang Q, Liu M, Zhao K, Xu X, Zhang J, Xu B. Hyperhomocysteinemia increases the risk of vertebrobasilar dissecting aneurysm among the male Han Chinese population: a retrospective case-control study. The International journal of neuroscience 2024. link 57 Buddeberg BS, Seeberger E, Bläsi C, Dutilh G, Steiner LA, Bandschapp O et al.. Is crystalloid co-loading necessary to prevent spinal hypotension during elective cesarean delivery? A randomized double-blind trial. International journal of obstetric anesthesia 2024. link 58 McGuire LS, Charbel FT. A narrative review of techniques for surgical revascularization of the extracranial vertebral artery in vertebrobasilar insufficiency. Neuro-Chirurgie 2024. link 59 Eley N, Kumar R, Ryan R, Sethi R. Vertebrobasilar Insufficiency Syndrome in Extension: Insights into Surgical Treatment. World neurosurgery 2024. link 60 Toghdory A, Asadi M, Ghoorchi T, Hatami M. Impacts of organic manganese supplementation on blood mineral, biochemical, and hematology in Afshari Ewes and their newborn lambs in the transition period. Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2023. link 61 Cordon IM, Doerr C, Whetstone L. California's Supplemental Nutrition Assistance Program-Education (SNAP-Ed) . Public health nutrition 2023. link 62 Persello A, Souab F, Dupas T, Aillerie V, Bigot E, Denis M et al.. A Rat Model of Clinically Relevant Extracorporeal Circulation Develops Early Organ Dysfunctions. International journal of molecular sciences 2023. link 63 Abdi-Moghadam Z, Darroudi M, Mahmoudzadeh M, Mohtashami M, Jamal AM, Shamloo E et al.. Functional yogurt, enriched and probiotic: A focus on human health. Clinical nutrition ESPEN 2023. link 64 Hannes F, Moon K, Moench Pfanner R. Optimizing health and nutrition status of migrant construction workers consuming multiple micronutrient fortified rice in Singapore. PloS one 2023. link 65 Plotnikoff GA, Dobberstein L, Raatz S. Nutritional Assessment of the Symptomatic Patient on a Plant-Based Diet: Seven Key Questions. Nutrients 2023. link 66 Micheletti C, Madeo G, Macchia A, Donato K, Cristoni S, Ceccarini MR et al.. Nutrigenomics: SNPs correlated to vitamins' deficiencies. La Clinica terapeutica 2023. link 67 Ahmad M, Hassan I, Shah MA, Gani A, Muthukumarappan K. Co-encapsulation of multivitamins in micro & nano-sized starch, target release, capsule characterization and interaction studies. International journal of biological macromolecules 2023. link 68 Kaim U, Goluch ZS. Health Benefits of Bread Fortification: A Systematic Review of Clinical Trials according to the PRISMA Statement. Nutrients 2023. link 69 El Finou H, Salhi N, Zaid A, El Rhaffari L. Consumption of food supplements in the Fes-Meknes region (Morocco); profiles and typology. Roczniki Panstwowego Zakladu Higieny 2023. link 70 Waksmańska W, Bobiński R. Vitamin content in the diet among 14- to 15-year-old teenagers depending on the BMI value. Minerva pediatrics 2023. link 71 Freitas MB, Castro IRR, Schincaglia RM, Carneiro LBV, Alves-Santos NH, Normando P et al.. Characterization of micronutrient supplements use by Brazilian children 6-59 months of age: Brazilian National Survey on Child Nutrition (ENANI-2019). Cadernos de saude publica 2023. link 72 White JM, Drummond E, Bijalwan V, Singhkumarwong A, Betigeri A, Blankenship J. Micronutrient gaps during the complementary feeding period in seven countries in Southeast Asia: A Comprehensive Nutrient Gap Assessment. Maternal & child nutrition 2023. link 73 Nardi KT, Sarturi JO, Huerta-Leidenz N, Henry DD, Woerner DR, Ciriaco FM et al.. The effects of a Nutritional Packet (live yeast, vitamins C and B1, and electrolytes) offered during the final phase of feedlot steers on growth performance, nutrient digestion, and feeding behavior. Journal of animal science 2023. link 74 Zhuang Y, Yin J, Han F, You J, Ding Y, Wang Z. Impact of Replacing Soft Drinks with Dairy Products on Micronutrient Intakes of Chinese Preschool Children: A Simulation Study. Nutrients 2023. link 75 Lip GY, Genaidy A, Estes C, McKay D, Falks T. Transient ischemic attack events and incident cardiovascular and non-cardiovascular complications: Observations from a large diversified multimorbid cohort. European stroke journal 2023. link 76 Gülaşti F, Gülaşti S, Sari S. Tricuspid annular plane systolic excursion to predict arterial hypotension caused by general anesthesia induction. Minerva anestesiologica 2023. link 77 Yao K, Zu HB. Isolated transient vertigo due to TIA: challenge for diagnosis and therapy. Journal of neurology 2023. link 78 Smith LJ, Gregory P, Clatworthy P, Gallop L, Stothart G. Working Memory Impairment in Transient Ischaemic Attack: N-back as a Sensitive Measure for Detection. Brain impairment : a multidisciplinary journal of the Australian Society for the Study of Brain Impairment 2023. link 79 Micieli A, Singh N, Jahn B, Siebert U, Menon BK, Demchuk AM. Cost-effectiveness of testing for CYP2C19 loss-of-function carriers following transient ischemic attack/minor stroke: A Canadian perspective. International journal of stroke : official journal of the International Stroke Society 2023. link 80 Wang L, Chaudhari K, Winters A, Sun Y, Berry R, Tang C et al.. Recurrent Transient Ischemic Attack Induces Neural Cytoskeleton Modification and Gliosis in an Experimental Model. Translational stroke research 2023. link 81 Ho R, McDonald C, Pauls JP, Li Z. 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    Original source

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      Observed Versus Predicted Stroke Risk After Transient Ischemic Attack: A Post Hoc Analysis of a Randomized Clinical Trial.Daghlas I, Caunca MR, Kim AS Journal of the American Heart Association (2026)
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      Nomogram Model for Predicting 90-Day Excellent Outcome in Patients With Acute Vertebrobasilar Artery Occlusion Undergoing Endovascular Thrombectomy.Pan S, Cao YZ, Lv PH, Ding Y, Liu Z, Sun W et al. Journal of the American Heart Association (2026)
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