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Urology22 papers

Calcium oxalate calculus of kidney

Last edited: 4/10/2026

Overview

Calcium oxalate (CaOx) kidney stones are a common condition with high global prevalence and recurrence rates 1. Macrophages play a significant role in the formation of CaOx stones, with research shifting towards understanding macrophage phenotypes and signaling pathways involved in this process 1.

Diagnosis

  • No diagnostic criteria or specific tests for CaOx calculus were mentioned in the provided abstracts.

    • Management

  • Targeting M2-like macrophage function may offer a therapeutic strategy for stone prevention 1.

    • Special Populations

  • No information on special populations was provided in the abstracts.

    • Key Recommendations

  • Consider targeting M2-like macrophage function as a potential therapeutic strategy for preventing calcium oxalate kidney stones. (Evidence: Weak)

    • References

    1 Taguchi K, Okada A, Unno R, Hamamoto S, Yasui T. Macrophage Function in Calcium Oxalate Kidney Stone Formation: A Systematic Review of Literature. Frontiers in immunology 2021. link

    Original source

    1. [1]
      Macrophage Function in Calcium Oxalate Kidney Stone Formation: A Systematic Review of Literature. — Taguchi K, Okada A, Unno R, Hamamoto S, Yasui T Frontiers in immunology (2021)
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