Overview
Schizophrenia is a common, severe, and usually chronic mental illness characterized by delusions, hallucinations, and significant functional and social disability 12. Maintenance treatment with antipsychotic drugs can prevent relapse but also causes side-effects 2.Diagnosis
No information provided in the abstracts.Management
Maintenance treatment with antipsychotic drugs (oral or long-acting injectable) can prevent relapse in adults with schizophrenia or schizoaffective disorder with stable symptoms 2.
Transitional discharge interventions may improve the general condition of users, level of functioning, use of health resources, and satisfaction with care 1.
Transitional discharge interventions coordinate different levels of the health system to guarantee continuity of care in the community and provide therapeutic relationships as a safety net during discharge and reintegration 1.Special Populations
No information provided in the abstracts.Key Recommendations
Maintenance treatment with antipsychotic drugs is recommended for adults with schizophrenia or schizoaffective disorder with stable symptoms to prevent relapse 2. (Evidence: Strong)
Transitional discharge interventions should be considered to support individuals with schizophrenia during the transition from hospital to the community, aiming to improve functioning and satisfaction with care 1. (Evidence: Moderate)References
1 Roson Rodriguez P, Chen X, Arancibia M, Garegnani L, Escobar Liquitay CM, Mohammad HA et al.. Transitional discharge interventions for people with schizophrenia. The Cochrane database of systematic reviews 2024. link
2 Schneider-Thoma J, Chalkou K, Dörries C, Bighelli I, Ceraso A, Huhn M et al.. Comparative efficacy and tolerability of 32 oral and long-acting injectable antipsychotics for the maintenance treatment of adults with schizophrenia: a systematic review and network meta-analysis. Lancet (London, England) 2022. link01997-8)