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Cardiology6 papers

Moderate tricuspid valve regurgitation

Last edited: 4/10/2026

Overview

Tricuspid regurgitation (TR) is a condition where the tricuspid valve does not close properly, allowing blood to leak backward into the right atrium. Moderate TR is associated with increased adverse outcomes in patients with heart failure 1.

Diagnosis

  • Tricuspid regurgitation is graded based on severity 1.
  • Echocardiography is the primary imaging modality for assessing TR severity.
  • Management

  • Management strategies for moderate TR are not detailed in the provided abstracts.
  • However, moderate and severe TR are associated with increased all-cause mortality and heart failure rehospitalization rates 1.
  • Key Recommendations

  • Moderate and severe tricuspid regurgitation are associated with increased all-cause mortality and heart failure rehospitalization rates in patients with heart failure 1. (Evidence: Moderate)
  • In patients with heart failure, moderate to severe TR is linked to higher all-cause mortality, heart failure rehospitalization rates, and cardiovascular mortality compared to no or mild TR 1. (Evidence: Moderate)
  • References

    1 Sun Z, Luo Y, Wang X, Chang T, Chang M, Cui Y et al.. Association between tricuspid regurgitation and heart failure outcomes: A meta-analysis. ESC heart failure 2025. link

    Original source

    1. [1]
      Association between tricuspid regurgitation and heart failure outcomes: A meta-analysis.Sun Z, Luo Y, Wang X, Chang T, Chang M, Cui Y et al. ESC heart failure (2025)

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