Clinical Presentation
An HIV-negative lung transplant recipient presented with fever, lung infiltrate, and acute kidney injury, indicative of disseminated E. cuniculi infection [PMID:23388129].
Diagnosis
Renal biopsy revealed granulomatous interstitial nephritis with characteristic 'belt-like stripe' organisms in tubular epithelial cells, confirmed by electron microscopy, PCR, and cell culture [PMID:23388129].
Management
The patient was treated with albendazole and had immunosuppressive therapy reduced, though clinical outcomes were complicated by other infections [PMID:23388129].
References
1 Levine DJ, Riley DJ, Jorgensen JH, McClain WD, Tio F, Visvesvara GS et al.. Key diagnostic features of granulomatous interstitial nephritis due to Encephalitozoon cuniculi in a lung transplant recipient. The American journal of surgical pathology 2013. link
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