Overview
Antral gastritis involves inflammation localized to the antrum of the stomach, often associated with various etiologies including Helicobacter pylori infection, autoimmune conditions, or as a complication in advanced malignancies 1.Diagnosis
Endoscopy with biopsy for histological confirmation 1.
Serology and urea breath tests for H. pylori infection 1.
Imaging studies (e.g., CT) may be indicated in complex cases or malignancy suspicion 1.Management
First-line treatments:
- Antibiotic therapy for H. pylori infection (specific regimens not detailed in abstracts) 1.
- Proton pump inhibitors (PPIs) for symptom control and healing 1.
Adjunctive treatments:
- Dietary modifications to avoid irritants 1.
- Symptomatic relief with antacids or H2 receptor antagonists 1.Special Populations
Advanced malignancies: Percutaneous transhepatic feeding jejunostomy may be considered in cases with advanced antral cancer affecting oral intake 1.Key Recommendations
Perform endoscopy with biopsy for definitive diagnosis of antral gastritis (Evidence: Moderate) 1.
Initiate PPI therapy alongside appropriate antibiotic treatment if H. pylori infection is confirmed (Evidence: Moderate) 1.
Consider percutaneous transhepatic feeding jejunostomy in patients with advanced antral cancer impacting nutritional intake (Evidence: Weak) 1.References
1 Haskell L, Gordon RL, Salomonowitz E, Ayalon A, Durst A. Technical developments and instrumentation: percutaneous transhepatic feeding jejunostomy. Journal of surgical oncology 1985. link