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Gastroenterology776 papers

Secondary diabetes mellitus

Last edited: 4/17/2026

Overview

Secondary diabetes mellitus refers to diabetes developing as a consequence of another condition, often involving pancreatic damage or dysfunction, such as chronic pancreatitis or pancreatic exocrine insufficiency 316.

Diagnosis

  • Clinical Presentation: Symptoms of diabetes alongside signs of underlying pancreatic disease 16.
  • Laboratory Tests: Fasting glucose levels, HbA1c, and pancreatic function tests (e.g., fecal elastase-1 for exocrine function) 3.
  • Imaging: CT or MRI to assess pancreatic morphology and identify structural abnormalities 218.
  • Genetic Testing: Consider in cases with familial patterns or specific syndromes 16.
  • Management

  • Address Underlying Condition: Treat the primary cause (e.g., managing chronic pancreatitis, surgical intervention for vascular anomalies) 618.
  • Glycemic Control: Initiate appropriate antidiabetic therapy (e.g., metformin, insulin) tailored to the patient's needs 16.
  • Nutritional Support: Consider pancreatic enzyme replacement therapy if exocrine insufficiency is present 3.
  • Multidisciplinary Care: Involvement of endocrinologists, gastroenterologists, and surgeons as needed 11.
  • Special Populations

  • Pregnancy: Management requires careful consideration of teratogenic risks and glycemic control; consult endocrinology and maternal-fetal medicine specialists 16.
  • Elderly: Focus on minimizing sedation risks during procedures like ERCP; consider less invasive sedation techniques 1920.
  • Comorbidities: Tailor sedation and procedural approaches to manage cardiovascular and respiratory risks, especially in high-risk patients 1924.
  • Key Recommendations

  • Identify and Treat Underlying Cause: Prioritize addressing the primary pancreatic pathology to potentially reverse or stabilize secondary diabetes (Evidence: Moderate 36).
  • Optimize Glycemic Control: Use individualized antidiabetic therapy, considering the severity and type of diabetes (Evidence: Moderate 16).
  • Consider Exocrine Support: Implement pancreatic enzyme replacement therapy if pancreatic exocrine insufficiency is diagnosed (Evidence: Moderate 3).
  • Multidisciplinary Approach: Engage a team of specialists to manage complex cases effectively (Evidence: Expert opinion 11).
  • Minimize Procedural Risks in Special Populations: Tailor sedation and procedural strategies to reduce complications in elderly and high-risk patients (Evidence: Moderate 1920).
  • References

    Showing 100 most recent of 142 indexed papers.

    1 Wang Q, Chen H, Lv Z, Zhang P, Li Y, Zhao C et al.. The molecular mechanism of cuproptosis and research progress in pancreatic diseases. Annals of medicine 2026. link 2 Darbhamulla S, Masuda H, Ng R, Shore T, Reidy B, Roseverne L et al.. The Utility of 24/7 Interventional Radiology Service Post-pancreaticoduodennectomy. Pancreas 2026. link 3 Dominguez-Muñoz JE, Vujasinovic M, de la Iglesia D, Cahen D, Capurso G, Gubergrits N et al.. European guidelines for the diagnosis and treatment of pancreatic exocrine insufficiency: UEG, EPC, EDS, ESPEN, ESPGHAN, ESDO, and ESPCG evidence-based recommendations. United European gastroenterology journal 2025. link 4 Jankowski WM, Fichna J, Tarasiuk-Zawadzka A. A systematic review of the relationship between gut microbiota and prevalence of pancreatic diseases. Microbial pathogenesis 2025. link 5 Wang Y, Su J, Liu X, Song H, Liu Z, Ren H et al.. Uric acid and related disorders in the risk of pancreatic diseases: A UK Biobank prospective study. Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2025. link 6 Li X, Hong W, Zou Z, Du J, Su R, Wang L et al.. Emergency pancreatoduodenectomy for non-traumatic conditions: a case series analysis. BMC gastroenterology 2025. link 7 Kim IJ, Choi GJ, Oh HC, Kang H. Comparison of Remimazolam and Propofol for Sedation in Endoscopic Retrograde Cholangiopancreatography: A Systematic Review and Meta-Analysis With Trial Sequential Analysis. Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society 2025. link 8 Iwata S, Iwashita T, Senju A, Tezuka R, Uemura S, Fukada M et al.. Successful Surgical Resection of Pancreatic Arteriovenous Malformation Complicated by Acute Pancreatitis. Internal medicine (Tokyo, Japan) 2025. link 9 Arino H, Wada M, Kobayashi H, Yoshida A, Oka S, Inokuma T. Metachronous Rupture of Pancreatoduodenal Artery Aneurysm with Median Arcuate Ligament Syndrome: A Case Report and Review of 11 Cases. Internal medicine (Tokyo, Japan) 2025. link 10 Löhr JM. Pancreas 2000. My journey with the central organ. Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2024. link 11 Domínguez Muñoz JE, Martínez Moneo E, Bolado Concejo F, Alberca de Las Parras F, Carballo Álvarez F, Elola Somoza FJ. Pancreas units within gastroenterology departments. Organizational and operational standards for a patient-centered service. Revista espanola de enfermedades digestivas 2024. link 12 Domínguez-Muñoz JE, Martínez Moneo E, Bolado Concejo F, Alberca de Las Parras F, Carballo Álvarez F, Elola Somoza FJ. Pancreas units within gastroenterology departments. Organizational and operational standards for a patient-centered service. Gastroenterologia y hepatologia 2024. link 13 Zhang W, Wang L, Zhu N, Wu W, Liu H. A prospective, randomized, single-blinded study comparing the efficacy and safety of dexmedetomidine and propofol for sedation during endoscopic retrograde cholangiopancreatography. BMC anesthesiology 2024. link 14 Li Z, Tabbara SO, Nwosu A, Souers RJ, Goyal A, Kurian EM et al.. Pancreaticobiliary Cytology Practice in 2021: Results of a College of American Pathologists Survey. Archives of pathology & laboratory medicine 2024. link 15 Vouros D, Bramis K, Alexakis N, Kotsarinis V, Antonakis P, Memos N et al.. Completion Pancreatectomy. Indications and Outcomes: A Systematic Review. The American surgeon 2023. link 16 Petrov MS. Fatty change of the pancreas: the Pandora's box of pancreatology. The lancet. Gastroenterology & hepatology 2023. link00064-X) 17 Singh J, Pathania J, Bodh V, Sharma R, Kumar R, Sharma B. Etomidate-ketamine versus dexmedetomidine-ketamine for entropy-guided procedural sedation during endoscopic retrograde cholangiopancreatography procedures: A randomized single blind study. Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology 2023. link 18 Anderloni A, Khalaf K. Recent Advances in Biliopancreatic Endoscopy. Medicina (Kaunas, Lithuania) 2022. link 19 Breazu CM, Alexa AL, Urs O, Mercea V, Tantau M, Bartos A et al.. Sedation for Endoscopic Retrograde Cholangiopancreatography in Elderly Patients - the Effect of Intravenous Lidocaine Infusion. A Randomised, Double-Blind, Placebo Controlled Trial. Journal of gastrointestinal and liver diseases : JGLD 2022. link 20 Hui RW, Leung CM. Patient-Controlled Sedation Versus Clinician-Administered Sedation for Endoscopic Retrograde Cholangiopancreatography: A Systematic Review. Anesthesia and analgesia 2022. link 21 Alzanbagi AB, Jilani TL, Qureshi LA, Ibrahim IM, Tashkandi AMS, Elshrief EEA et al.. Randomized trial comparing general anesthesia with anesthesiologist-administered deep sedation for ERCP in average-risk patients. Gastrointestinal endoscopy 2022. link 22 Deter RL, Dicker P, Lee W, Tully EC, Cody F, Malone FD et al.. Growth patterns and cardiovascular abnormalities in SGA fetuses: 2. Normal growth and progressive growth restriction. The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2022. link 23 Deter RL, Lee W, Dicker P, Tully EC, Cody F, Malone FD et al.. Growth patterns and cardiovascular abnormalities in SGA fetuses: 3. Late, adaptive and recovering growth restriction. The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2022. link 24 Gorris M, Hoogenboom SA, Wallace MB, van Hooft JE. Artificial intelligence for the management of pancreatic diseases. Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society 2021. link 25 Tamura N, Hanaoka T, Ito K, Araki A, Miyashita C, Ito S et al.. Mediating Factors Between Parental Socioeconomic Status and Small for Gestational Age in Infants: Results from the Hokkaido Study on Environment and Children's Health. Maternal and child health journal 2021. link 26 Guo P, Wu H, Liu L, Zhao Q, Jin Z. Efficacy of an Oxycodone-Propofol Combination versus a Fentanyl-Propofol Combination in Conscious Sedation during Therapeutic Endoscopic Retrograde Cholangiopancreatography in Elderly Patients. Gerontology 2021. link 27 Paul J, Shihaz AVH. PANCREATIC STEATOSIS: A NEW DIAGNOSIS AND THERAPEUTIC CHALLENGE IN GASTROENTEROLOGY. Arquivos de gastroenterologia 2020. link 28 Tsen A, Han S, Moreau C, Akshintala VS, Yazici C, Archibugi L et al.. The State of Mentorship and Pancreatic Research Among Trainees in Pancreatology: A Multinational Survey Study. Pancreas 2020. link 29 Chen TH, Su CH, Hsiao CY, Kao SY, Tsai PJ. Preemptive light sedation in intensive care unit may reduce pulmonary complications in geriatrics receiving pancreaticoduodenectomy. Journal of the Chinese Medical Association : JCMA 2020. link 30 Lee JG, Yoo KS, Byun YJ. Continuous infusion versus intermittent bolus injection of propofol during endoscopic retrograde cholangiopancreatography. The Korean journal of internal medicine 2020. link 31 Mani C, Kochhar P, Ravikumar G, Dwarkanath P, Sheela CN, George S et al.. Placental expression of ENG, VEGF, and FLT: Gender-specific associations with maternal vitamin B. European journal of clinical nutrition 2020. link 32 Ramiro Pumar G, Mendoza Jiménez-Ridruejo J, Santander Vaquero C. Hemosuccus pancreaticus: a rare cause of gastrointestinal bleeding. Revista espanola de enfermedades digestivas 2019. link 33 Ibiebele I, Bowen JR, Nippita TA, Morris JM, Ford JB. Childhood health and education outcomes following early term induction for large-for-gestational age: A population-based record linkage study. Acta obstetricia et gynecologica Scandinavica 2019. link 34 Smith ZL, Mullady DK, Lang GD, Das KK, Hovis RM, Patel RS et al.. A randomized controlled trial evaluating general endotracheal anesthesia versus monitored anesthesia care and the incidence of sedation-related adverse events during ERCP in high-risk patients. Gastrointestinal endoscopy 2019. link 35 Kumar M, Santhanam S, Thomas N, Jana AK. A prospective observational study comparing cardiac function of small for gestational age with appropriate for gestational age babies using serial echocardiographic studies. The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2019. link 36 Lu Z, Li W, Chen H, Qian Y. Efficacy of a Dexmedetomidine-Remifentanil Combination Compared with a Midazolam-Remifentanil Combination for Conscious Sedation During Therapeutic Endoscopic Retrograde Cholangio-Pancreatography: A Prospective, Randomized, Single-Blinded Preliminary Trial. Digestive diseases and sciences 2018. link 37 Zhou Y, Wang W, Shi Y, Lu X, Zhan Q, Chen H et al.. Substantial atherosclerotic celiac axis stenosis is a new risk factor for biliary fistula after pancreaticoduodenectomy. International journal of surgery (London, England) 2018. link 38 Sun GQ, Gao BF, Li GJ, Lei YL, Li J. Application of remifentanil for conscious sedation and analgesia in short-term ERCP and EST surgery. Medicine 2017. link 39 Eberl S, Koers L, van Hooft JE, de Jong E, Schneider T, Hollmann MW et al.. Sedation with propofol during ERCP: is the combination with esketamine more effective and safer than with alfentanil? Study protocol for a randomized controlled trial. Trials 2017. link 40 Sun N, Lu G, Zhang L, Wang X, Gao C, Bi J et al.. Clinical efficacy of spleen-preserving distal pancreatectomy with or without splenic vessel preservation: A Meta-analysis. Medicine 2017. link 41 Chen Y, Zhu B, Wu X, Li S, Tao F. Association between maternal vitamin D deficiency and small for gestational age: evidence from a meta-analysis of prospective cohort studies. BMJ open 2017. link 42 Aurensanz Clemente E, Ayerza Casas A, Samper Villagrasa P, Ruiz Frontera P, Bueno Lozano G. Evaluation of cardiac function in a group of small for gestational age school-age children treated with growth hormone. Medicina clinica 2017. link 43 Kennedy GT, McMillan MT, Sprys MH, Bassi C, Greig PD, Hansen PD et al.. The influence of fellowship training on the practice of pancreatoduodenectomy. HPB : the official journal of the International Hepato Pancreato Biliary Association 2016. link 44 Gani F, Kim Y, Weiss MJ, Makary MA, Wolfgang CL, Hirose K et al.. Effect of surgeon and anesthesiologist volume on surgical outcomes. The Journal of surgical research 2016. link 45 Zhang J, Huang Y, Li Z, Li J, Liu K, Li C. Sedation and use of analgesics in endoscopic retrograde cholangiopancreatography: a double-blind comparison study of meperidine/midazolam, remifentanil/ midazolam, and remifentanil alone. International journal of clinical pharmacology and therapeutics 2016. link 46 Seto TL, Tabangin ME, Langdon G, Mangeot C, Dawodu A, Steinhoff M et al.. Racial disparities in cord blood vitamin D levels and its association with small-for-gestational-age infants. Journal of perinatology : official journal of the California Perinatal Association 2016. link 47 Peralta G, Gerstein WH, Roldan CA, Fleming H. Pancreaticopericardial Fistula Treated Successfully With Pericardial and Pancreatic Drains. The Canadian journal of cardiology 2016. link 48 Whitcomb DC. Innovation and hard work: The 2015 George E. Palade Medal Award Lecture. Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2015. link 49 Nilsson A, Grossmann B, Kullman E, Uustal E, Sjöberg F, Nilsson L. Sedation during endoscopic retrograde cholangiopancreatography: a randomized controlled study of patient-controlled propofol sedation and that given by a nurse anesthetist. Scandinavian journal of gastroenterology 2015. link 50 Haytural C, Aydınlı B, Demir B, Bozkurt E, Parlak E, Dişibeyaz S et al.. Comparison of Propofol, Propofol-Remifentanil, and Propofol-Fentanyl Administrations with Each Other Used for the Sedation of Patients to Undergo ERCP. BioMed research international 2015. link 51 Fassoulaki A, Iatrelli I, Vezakis A, Polydorou A. Deep sedation for endoscopic cholangiopancreatography with or without pre or intraprocedural opioids: A double-blind randomised controlled trial. European journal of anaesthesiology 2015. link 52 Narayanan S, Shannon A, Nandalan S, Jaitly V, Greer S. Alternative sedation for the higher risk endoscopy: a randomized controlled trial of ketamine use in endoscopic retrograde cholangiopancreatography. Scandinavian journal of gastroenterology 2015. link 53 Morisset J. Seventy years of pancreatic physiology: take a look back. Pancreas 2014. link 54 Tucker Edmonds B, McKenzie F, Fadel WF, Matthias MS, Salyers MP, Barnato AE et al.. Using simulation to assess the influence of race and insurer on shared decision making in periviable counseling. Simulation in healthcare : journal of the Society for Simulation in Healthcare 2014. link 55 Lee BS, Ryu J, Lee SH, Lee MG, Jang SE, Hwang JH et al.. Midazolam with meperidine and dexmedetomidine vs. midazolam with meperidine for sedation during ERCP: prospective, randomized, double-blinded trial. Endoscopy 2014. link 56 Jilesen AP, Tol JA, Busch OR, van Delden OM, van Gulik TM, Nieveen van Dijkum EJ et al.. Emergency management in patients with late hemorrhage after pancreatoduodenectomy for a periampullary tumor. World journal of surgery 2014. link 57 Casadei R, Ricci C, Giampalma E, D'Ambra M, Taffurelli G, Mosconi C et al.. Interventional radiology procedures after pancreatic resections for pancreatic and periampullary diseases. JOP : Journal of the pancreas 2014. link 58 Kang CM, Chung YE, Jung MJ, Hwang HK, Choi SH, Lee WJ. Splenic vein thrombosis and pancreatic fistula after minimally invasive distal pancreatectomy. The British journal of surgery 2014. link 59 Bens S, Haake A, Richter J, Leohold J, Kolarova J, Vater I et al.. Frequency and characterization of DNA methylation defects in children born SGA. European journal of human genetics : EJHG 2013. link 60 Barnett SR, Berzin T, Sanaka S, Pleskow D, Sawhney M, Chuttani R. Deep sedation without intubation for ERCP is appropriate in healthier, non-obese patients. Digestive diseases and sciences 2013. link 61 Mazanikov M, Udd M, Kylänpää L, Mustonen H, Lindström O, Färkkilä M et al.. A randomized comparison of target-controlled propofol infusion and patient-controlled sedation during ERCP. Endoscopy 2013. link 62 Garewal D, Vele L, Waikar P. Anaesthetic considerations for endoscopic retrograde cholangio-pancreatography procedures. Current opinion in anaesthesiology 2013. link 63 Christie A, Robertson I, Moss J. Interventional radiology emergency service provision for a large UK urban population: initial 3.5 years of experience. Clinical radiology 2013. link 64 Gawlas I, Sethi M, Winner M, Epelboym I, Lee JL, Schrope BA et al.. Readmission after pancreatic resection is not an appropriate measure of quality. Annals of surgical oncology 2013. link 65 Polkowski M, Larghi A, Weynand B, Boustière C, Giovannini M, Pujol B et al.. Learning, techniques, and complications of endoscopic ultrasound (EUS)-guided sampling in gastroenterology: European Society of Gastrointestinal Endoscopy (ESGE) Technical Guideline. Endoscopy 2012. link 66 Fabbri LP, Nucera M, Marsili M, Al Malyan M, Becchi C. Ketamine, propofol and low dose remifentanil versus propofol and remifentanil for ERCP outside the operating room: is ketamine not only a "rescue drug"?. Medical science monitor : international medical journal of experimental and clinical research 2012. link 67 Grasso RF, Cazzato RL, Luppi G, Faiella E, Del Vescovo R, Giurazza F et al.. Pancreatic arteriovenous malformation involving the duodenum embolized with ethylene-vinyl alcohol copolymer (Onyx). Cardiovascular and interventional radiology 2012. link 68 Lordan JT, Woods J, Keeling P, Paterson IM. A retrospective analysis of benzodiazepine sedation vs. propofol anaesthesia in 252 patients undergoing endoscopic retrograde cholangiopancreatography. HPB : the official journal of the International Hepato Pancreato Biliary Association 2011. link 69 Berzin TM, Sanaka S, Barnett SR, Sundar E, Sepe PS, Jakubowski M et al.. A prospective assessment of sedation-related adverse events and patient and endoscopist satisfaction in ERCP with anesthesiologist-administered sedation. Gastrointestinal endoscopy 2011. link 70 Bilge I, Poyrazoglu S, Bas F, Emre S, Sirin A, Gokalp S et al.. Ambulatory blood pressure monitoring and renal functions in term small-for-gestational age children. Pediatric nephrology (Berlin, Germany) 2011. link 71 Fernández-Zapico ME. 'Maintain focus and aim high'. An interview with Dr. Chung Owyang, H. Marvin Pollard Collegiate Professor, Department of Internal Medicine, University of Michigan, Ann Arbor, mMch., USA. Interviewed by Martín E Fernández-Zapico. Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2010. link 72 De Reu PA, Oosterbaan HP, Smits LJ, Nijhuis JG. Avoidable mortality in small-for-gestational-age children in the Netherlands. Journal of perinatal medicine 2010. link 73 Bradley TJ, Potts JE, Lee SK, Potts MT, De Souza AM, Sandor GG. Early changes in the biophysical properties of the aorta in pre-adolescent children born small for gestational age. The Journal of pediatrics 2010. link 74 Okah FA, Hoff GL, Dew PC, Cai J. Ponderal index of the newborn: effect of smoking on the index of the small-for-gestational-age infant. American journal of perinatology 2010. link 75 Lomberk G. Funding opportunities for rare pancreatic diseases. Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2009. link 76 Petersen OH. 'Now we have to use the skills we have developed in cell physiological studies to attack the most crucial problems in pancreatic pathology': an interview with Ole H. Petersen, Medical Research Council Professor of Physiology, University of Liverpool, UK. [Interview by Martín E Fernández-Zapico]. Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2009. link 77 Colak MC, Kocaturk H, Bayram E, Karaca L. Inferior pancreaticoduodenal artery false aneurysm: a rare cause of gastrointestinal bleeding diagnosed by three-dimensional computed tomography. Singapore medical journal 2009. link 78 Lomberk G. Societies. Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2008. link 79 Rajesh G, Nair AS, Narayanan VA, Balakrishnan V. Tropical pancreatitis and fibrocalculous pancreatic diabetes--two sides of the same coin?. Tropical gastroenterology : official journal of the Digestive Diseases Foundation 2008. link 80 Paspatis GA, Manolaraki MM, Vardas E, Theodoropoulou A, Chlouverakis G. Deep sedation for endoscopic retrograde cholangiopancreatography: intravenous propofol alone versus intravenous propofol with oral midazolam premedication. Endoscopy 2008. link 81 Pisello F, Geraci G, Facella T, Li Volsi F, Modica G, Sciumè C. What to do when endoscopic retrograde cholangio-pancreatography fails? Personal experience. Il Giornale di chirurgia 2008. link 82 Shreeve DR. Professor HT (Harry) Howat: prime leader in pancreatology development in the UK. The journal of the Royal College of Physicians of Edinburgh 2007. link 83 Urrutia R. The future of pancreatology: how to go where we have never been before. American journal of surgery 2007. link 84 Yüksel O, Parlak E, Köklü S, Ertugrul I, Tunç B, Sahin B. Conscious sedation during endoscopic retrograde cholangiopancreatography: midazolam or midazolam plus meperidine?. European journal of gastroenterology & hepatology 2007. link 85 Ong WC, Santosh D, Lakhtakia S, Reddy DN. A randomized controlled trial on use of propofol alone versus propofol with midazolam, ketamine, and pentazocine "sedato-analgesic cocktail" for sedation during ERCP. Endoscopy 2007. link 86 Künzli BM, Berberat PO, Giese T, Csizmadia E, Kaczmarek E, Baker C et al.. Upregulation of CD39/NTPDases and P2 receptors in human pancreatic disease. American journal of physiology. Gastrointestinal and liver physiology 2007. link 87 Vaysse N. 'You can do it!' Nicole Vaysse is interviewed by Matin E. Fernandez-Zapico. Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2006. link 88 Uchida E, Aimoto T, Nakamura Y, Katsuno A, Chou K, Kawamoto M et al.. Pancreatic arteriovenous malformation involving adjacent duodenum with gastrointestinal bleeding: report of a case. Journal of Nippon Medical School = Nippon Ika Daigaku zasshi 2006. link 89 Poland D. Universal scaling of the C--G distribution of genes. Biophysical chemistry 2005. link 90 Mazzon D, Germanà B, Poole D, Celato M, Bernardi L, Calleri G et al.. Conscious sedation during endoscopic retrograde colangiopancreatography: implementation of SIED-SIAARTI-ANOTE guidelines in Belluno Hospital. Minerva anestesiologica 2005. link 91 Riphaus A, Stergiou N, Wehrmann T. Sedation with propofol for routine ERCP in high-risk octogenarians: a randomized, controlled study. The American journal of gastroenterology 2005. link 92 Strambi M, Vezzosi P, Buoni S, Berni S, Longini M. Blood pressure in the small-for-gestational age newborn. Minerva pediatrica 2004. link 93 Konturek SJ, Zabielski R, Konturek JW, Czarnecki J. Neuroendocrinology of the pancreas; role of brain-gut axis in pancreatic secretion. European journal of pharmacology 2003. link 94 Ankorina-Stark I, Amstrup J, Novak I. Regulation of the Na+/Ca2+ exchanger in rat pancreatic ducts. The Journal of membrane biology 2002. link 95 Iwashita Y, Kawano T, Maeda T, Nagasaki S, Kitano S. Pancreatic arteriovenous malformation treated by transcatheter embolization. Hepato-gastroenterology 2002. link 96 Baron JH. The pancreas. The Mount Sinai journal of medicine, New York 2000. link 97 Jung M, Hofmann C, Kiesslich R, Brackertz A. Improved sedation in diagnostic and therapeutic ERCP: propofol is an alternative to midazolam. Endoscopy 2000. link 98 Wehrmann T, Kokabpick S, Lembcke B, Caspary WF, Seifert H. Efficacy and safety of intravenous propofol sedation during routine ERCP: a prospective, controlled study. Gastrointestinal endoscopy 1999. link70281-6) 99 Clausson B, Cnattingius S, Axelsson O. Preterm and term births of small for gestational age infants: a population-based study of risk factors among nulliparous women. British journal of obstetrics and gynaecology 1998. link 100 Berney T, Pretre R, Chassot G, Morel P. The role of revascularization in celiac occlusion and pancreatoduodenectomy. American journal of surgery 1998. link00195-0)

    Original source

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      The molecular mechanism of cuproptosis and research progress in pancreatic diseases.Wang Q, Chen H, Lv Z, Zhang P, Li Y, Zhao C et al. Annals of medicine (2026)
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      The Utility of 24/7 Interventional Radiology Service Post-pancreaticoduodennectomy.Darbhamulla S, Masuda H, Ng R, Shore T, Reidy B, Roseverne L et al. Pancreas (2026)
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      European guidelines for the diagnosis and treatment of pancreatic exocrine insufficiency: UEG, EPC, EDS, ESPEN, ESPGHAN, ESDO, and ESPCG evidence-based recommendations.Dominguez-Muñoz JE, Vujasinovic M, de la Iglesia D, Cahen D, Capurso G, Gubergrits N et al. United European gastroenterology journal (2025)
    4. [4]
      A systematic review of the relationship between gut microbiota and prevalence of pancreatic diseases.Jankowski WM, Fichna J, Tarasiuk-Zawadzka A Microbial pathogenesis (2025)
    5. [5]
      Uric acid and related disorders in the risk of pancreatic diseases: A UK Biobank prospective study.Wang Y, Su J, Liu X, Song H, Liu Z, Ren H et al. Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] (2025)
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      Emergency pancreatoduodenectomy for non-traumatic conditions: a case series analysis.Li X, Hong W, Zou Z, Du J, Su R, Wang L et al. BMC gastroenterology (2025)
    7. [7]
      Comparison of Remimazolam and Propofol for Sedation in Endoscopic Retrograde Cholangiopancreatography: A Systematic Review and Meta-Analysis With Trial Sequential Analysis.Kim IJ, Choi GJ, Oh HC, Kang H Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society (2025)
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      Successful Surgical Resection of Pancreatic Arteriovenous Malformation Complicated by Acute Pancreatitis.Iwata S, Iwashita T, Senju A, Tezuka R, Uemura S, Fukada M et al. Internal medicine (Tokyo, Japan) (2025)
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      Metachronous Rupture of Pancreatoduodenal Artery Aneurysm with Median Arcuate Ligament Syndrome: A Case Report and Review of 11 Cases.Arino H, Wada M, Kobayashi H, Yoshida A, Oka S, Inokuma T Internal medicine (Tokyo, Japan) (2025)
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      Pancreas 2000. My journey with the central organ.Löhr JM Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] (2024)
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      Pancreas units within gastroenterology departments. Organizational and operational standards for a patient-centered service.Domínguez-Muñoz JE, Martínez Moneo E, Bolado Concejo F, Alberca de Las Parras F, Carballo Álvarez F, Elola Somoza FJ Gastroenterologia y hepatologia (2024)
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      Pancreaticobiliary Cytology Practice in 2021: Results of a College of American Pathologists Survey.Li Z, Tabbara SO, Nwosu A, Souers RJ, Goyal A, Kurian EM et al. Archives of pathology & laboratory medicine (2024)
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      Completion Pancreatectomy. Indications and Outcomes: A Systematic Review.Vouros D, Bramis K, Alexakis N, Kotsarinis V, Antonakis P, Memos N et al. The American surgeon (2023)
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      Fatty change of the pancreas: the Pandora's box of pancreatology.Petrov MS The lancet. Gastroenterology & hepatology (2023)
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      Etomidate-ketamine versus dexmedetomidine-ketamine for entropy-guided procedural sedation during endoscopic retrograde cholangiopancreatography procedures: A randomized single blind study.Singh J, Pathania J, Bodh V, Sharma R, Kumar R, Sharma B Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology (2023)
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      Sedation for Endoscopic Retrograde Cholangiopancreatography in Elderly Patients - the Effect of Intravenous Lidocaine Infusion. A Randomised, Double-Blind, Placebo Controlled Trial.Breazu CM, Alexa AL, Urs O, Mercea V, Tantau M, Bartos A et al. Journal of gastrointestinal and liver diseases : JGLD (2022)
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