Overview
The primary tuberculous complex refers to the initial site of infection and the associated lymph node involvement in tuberculosis. It is a key concept in understanding the pathogenesis and initial presentation of tuberculosis, particularly in children.Diagnosis
Low-complexity automated nucleic acid amplification tests (LC-aNAATs) are recommended for the simultaneous detection of Mycobacterium tuberculosis* complex and rifampicin resistance in non-respiratory specimens for extrapulmonary tuberculosis 1.Management
Special Populations
Key Recommendations
References
1 Kohli M, Inbaraj LR, Salomon A, Scandrett K, Korobitsyn A, Ismail N et al.. Low-complexity automated nucleic acid amplification tests for extrapulmonary tuberculosis and rifampicin resistance in adults and adolescents. The Cochrane database of systematic reviews 2025. link 2 Haraka F, Kakolwa M, Schumacher SG, Nathavitharana RR, Denkinger CM, Gagneux S et al.. Impact of the diagnostic test Xpert MTB/RIF on patient outcomes for tuberculosis. The Cochrane database of systematic reviews 2021. link