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Oncology2 papers

Benign neoplasm of anal canal

Last edited: 4/16/2026

Overview

Benign neoplasms of the anal canal are rare tumors that originate from various cell types, including apocrine sweat glands. These lesions are typically asymptomatic but can present as masses in the anal region 1.

Diagnosis

  • Clinical examination often reveals a palpable mass in the anal canal or perianal region.
  • Histopathological examination is crucial for definitive diagnosis, identifying specific cellular characteristics such as those seen in apocrine fibroadenomas.
  • Imaging studies (e.g., MRI, ultrasound) may be used to assess extent and relationship to surrounding structures but are not primary diagnostic tools 1.

    • Management

  • Surgical excision is the primary treatment modality, aiming for complete removal with clear margins.
  • Recurrence is rare but should be monitored in cases where complete excision is challenging.
  • No specific drug therapy is indicated for benign neoplasms of the anal canal 1.

    • Special Populations

  • No specific management guidelines are provided for pregnancy, pediatrics, elderly, or patients with comorbidities based on the given abstracts 1.

    • Key Recommendations

  • Definitive diagnosis requires histopathological examination of the lesion 1 (Evidence: Expert opinion).
  • Surgical excision should be performed for symptomatic or suspicious lesions to ensure complete removal 1 (Evidence: Expert opinion).
  • Regular follow-up is recommended post-excision to monitor for recurrence, particularly in cases with incomplete excision 1 (Evidence: Expert opinion).

    • References

    1 Assor D, Davis JB. Multiple apocrine fibroadenomas of the anal skin. American journal of clinical pathology 1977. link

    Original source

    1. [1]
      Multiple apocrine fibroadenomas of the anal skin. — Assor D, Davis JB American journal of clinical pathology (1977)
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