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Cardiology57 papers

Hemangioma of liver

Last edited: 4/14/2026

Overview

Hepatic hemangiomas are benign vascular tumors characterized by dilated sinusoidal spaces within liver parenchyma. They are typically asymptomatic and discovered incidentally, though complications such as pain, bleeding, or compression can occur 234.

Diagnosis

  • Imaging: Ultrasound (US), CT, MRI, and contrast-enhanced ultrasound (CEUS) are primary diagnostic tools 12.
  • CEUS Artifacts: Recognize "pseudowashout" artifacts that can mimic complications like necrosis 1.
  • Grading: Size classification (e.g., giant hemangiomas > 10 cm) aids in management decisions 2.
  • Differential Diagnosis: Rule out other liver lesions including malignancies through imaging characteristics and clinical context 2.
  • Management

  • Conservative Management: Recommended for asymptomatic lesions 2.
  • Surgical Intervention: Indicated for symptomatic lesions, complications (e.g., abscess formation), or large hemangiomas requiring resection 45.
  • Hemorrhage Control: Teflon strips sutured with catgut for controlling bleeding during resection 5.
  • Special Populations

  • Comorbidities: Abdominal pain in patients with hemangiomas may be associated with irritable bowel syndrome or other gastrointestinal diseases 2.
  • Giant Hemangiomas: Higher risk of complications necessitates closer monitoring and potential surgical intervention 24.
  • Key Recommendations

  • Monitor Asymptomatic Lesions: Regular imaging follow-up is advised for asymptomatic patients to detect any changes 2 (Evidence: Moderate).
  • Surgical Consideration for Symptomatic or Giant Lesions: Consider surgical resection for symptomatic lesions or those exceeding 10 cm to prevent complications 24 (Evidence: Moderate).
  • Recognize Pseudowashout Artifacts: Be aware of CEUS artifacts that can mimic complications to avoid unnecessary interventions 1 (Evidence: Expert opinion).
  • References

    1 Papachristodoulou A, Rafailidis V, Chartambilas E, Yusuf GT, Prassopoulos P. "Pseudowashout" artifact on liver haemangioma on CEUS: what to expect and how to avoid!. Medical ultrasonography 2022. link 2 Etemadi A, Golozar A, Ghassabian A, Zarei M, Hashemi Taheri AP, Dawsey SM et al.. Cavernous hemangioma of the liver: factors affecting disease progression in general hepatology practice. European journal of gastroenterology & hepatology 2011. link 3 Jayanthi V, Shankar TR, Ravindran C, Sudalaimuthu S, Chandrasekar TS. Diffuse hepatic hemangiomatosis: case report. Tropical gastroenterology : official journal of the Digestive Diseases Foundation 2000. link 4 Sharma V, Chaudhuri MM, Chandra AK. Giant cavernous hemangioma of liver. Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology 1991. link 5 Butsch JL, Butsch DW. A method of controlling hemorrhage for resection of massive hemangiomas of the liver. The American surgeon 1984. link

    Original source

    1. [1]
      "Pseudowashout" artifact on liver haemangioma on CEUS: what to expect and how to avoid!Papachristodoulou A, Rafailidis V, Chartambilas E, Yusuf GT, Prassopoulos P Medical ultrasonography (2022)
    2. [2]
      Cavernous hemangioma of the liver: factors affecting disease progression in general hepatology practice.Etemadi A, Golozar A, Ghassabian A, Zarei M, Hashemi Taheri AP, Dawsey SM et al. European journal of gastroenterology & hepatology (2011)
    3. [3]
      Diffuse hepatic hemangiomatosis: case report.Jayanthi V, Shankar TR, Ravindran C, Sudalaimuthu S, Chandrasekar TS Tropical gastroenterology : official journal of the Digestive Diseases Foundation (2000)
    4. [4]
      Giant cavernous hemangioma of liver.Sharma V, Chaudhuri MM, Chandra AK Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology (1991)
    5. [5]

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