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Anesthesiology20 papers

Neoplasm of uncertain behavior of coccygeal body

Last edited: 4/15/2026

Overview

Neoplasm of uncertain behavior of the coccygeal body refers to a mass in the coccyx region whose biological behavior cannot be definitively classified as benign or malignant based on initial evaluation. 3

Diagnosis

  • Imaging studies (e.g., MRI, CT) are essential for characterization of the mass 3.
  • Histopathological examination via biopsy is crucial for determining behavior but may not always be conclusive 3.
  • Clinical history and symptoms (e.g., pain, mass effect) guide suspicion 3.
  • Management

  • Non-operative therapy (e.g., conservative management, pain control) is often attempted initially but frequently fails 3.
  • Total coccygectomy may be considered for symptomatic relief in cases refractory to conservative treatment 3.
  • Surgical excision of perineural cysts causing coccygodynia can provide pain relief 4.
  • Special Populations

  • No specific data provided regarding pregnancy, pediatrics, or elderly populations 1234.
  • Key Recommendations

  • Initiate with non-operative management including pain control and conservative measures for coccygeal neoplasms of uncertain behavior 3 (Evidence: Moderate).
  • Consider total coccygectomy for patients with persistent symptoms despite non-operative treatment, given high satisfaction rates 3 (Evidence: Moderate).
  • Exclude other causes of coccygeal pain, such as perineural cysts, through imaging and targeted surgical intervention if indicated 4 (Evidence: Weak).
  • References

    1 Herold N, Spray S, Horn T, Henriksen SJ. Measurements of behavior in the naked mole-rat after intraperitoneal implantation of a radio-telemetry system. Journal of neuroscience methods 1998. link00028-4) 2 Zayer M. Coccygodynia. The Ulster medical journal 1996. link 3 Grosso NP, van Dam BE. Total coccygectomy for the relief of coccygodynia: a retrospective review. Journal of spinal disorders 1995. link 4 Ziegler DK, Batnitzky S. Coccygodynia caused by perineural cyst. Neurology 1984. link

    Original source

    1. [1]
      Measurements of behavior in the naked mole-rat after intraperitoneal implantation of a radio-telemetry system.Herold N, Spray S, Horn T, Henriksen SJ Journal of neuroscience methods (1998)
    2. [2]
      Coccygodynia.Zayer M The Ulster medical journal (1996)
    3. [3]
      Total coccygectomy for the relief of coccygodynia: a retrospective review.Grosso NP, van Dam BE Journal of spinal disorders (1995)
    4. [4]
      Coccygodynia caused by perineural cyst.Ziegler DK, Batnitzky S Neurology (1984)

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