Sudden cardiac death

Overview

Diagnosis

Management

Special Populations

Key Recommendations

References

Showing 100 most recent of 428 indexed papers.

1 Youssfi Y, Fanet L, Beganton F, Dumas F, Cariou A, Empana JP et al.. One year healthcare consumption prior to sudden cardiac death. European heart journal. Quality of care & clinical outcomes 2026. link 2 Avison A, Pyle WG, Sears W, Physick-Sheard PW. QT interval and cardiac restitution dynamics in racehorses: observations during maximal effort. American journal of physiology. Heart and circulatory physiology 2026. link 3 Cerra L, Nardi E, Aulino G, Polacco M, Oliva A, Arena V. Left ventricular false tendons as incidental findings in a case of sudden cardiac death: What is their role?. Journal of forensic and legal medicine 2026. link 4 Barranco R, Caristo I, Molinelli A, Rocca G, Vernazza N, Ventura F. Update on the similarities between SADS, SIDS, and SUDEP: Three sides of the same pyramid?. International journal of legal medicine 2026. link 5 MacLachlan H, Bhatia R, Raju H, Mellor G, Androulakis E, Basu J et al.. Cardiac Screening for Conditions Associated With Sudden Cardiac Death: Yield, Interventions, and SCA/SCD Incidence in 104,369 Young Individuals. Journal of the American College of Cardiology 2026. link 6 Salzillo C, Marzullo A. Post-mortem genetic testing: Role in sudden cardiac death in the young. Forensic science international. Genetics 2026. link 7 Fan ZH, Yue ZQ, Liu ZK, Jin ZF, Zhang WH, Chen H. Integrative Proteomic and Transcriptomic Profiling Identifies Candidate Biomarkers for Discriminating Anaphylactic from Cardiac Sudden Death. International journal of molecular sciences 2026. link 8 Kamar AAM, Mavroudis I, Ciobica A, Gheban D. Salivary Redox Biomarkers as a Non-Invasive Research Framework for Exploring Redox-Related Cardiac Electrical Vulnerability in Sudden Unexplained Cardiac Death: A Mechanistic and Narrative Review. Medicina (Kaunas, Lithuania) 2026. link 9 Fastenrath F, Sattler K, Duerschmied D, Lewandowski M, Akin I, Kuschyk J. Contemporary implantable cardiac device trials for sudden cardiac death and future guidelines: how can we shape the future?. Expert review of cardiovascular therapy 2026. link 10 Kinney HC. Reflections on a Career in Pediatric Neuropathology, with a Note of Gratitude. Annual review of pathology 2025. link 11 Torell MF, Svennblad B, Wisten A, Börjesson E, Bergfeldt L, Stattin EL et al.. Sudden Arrhythmic Death Syndrome in the Young: Risk Factors are Identifiable Prior to Sudden Cardiac Arrest. The American journal of cardiology 2025. link 12 Rhee TM, Lee KY, Choi J, Choi EK, Ahn HJ, Lee SR et al.. Neuroticism and sudden cardiac death: a prospective cohort study from UK biobank. Clinical research in cardiology : official journal of the German Cardiac Society 2025. link 13 Lüker J, Strik M, Andrade JG, Raymond-Paquin A, Elrefai MH, Roberts PR et al.. Incidence of premature battery depletion in subcutaneous cardioverter-defibrillator patients: insights from a multicenter registry. Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing 2025. link 14 Blanco-Verea A, Carracedo Á, Brion M. Challenges of genetics in the diagnosis of sudden cardiac death. Interest for forensic and legal medicine. Medicina clinica 2025. link 15 Nossen M, Andersen GØ. A man in his 30s with cardiac arrest. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 2025. link 16 Chauhan K, Royse A, Goh I, Crozier I, Wynn G. Oldest-in-Human Successful Extraction Experience of a Novel Substernal Extravascular Defibrillator. Journal of cardiovascular electrophysiology 2025. link 17 Katapadi A, Lakkireddy A, Korlakunta S, Maganti L, Ghazal R, Mudr AM et al.. A novel scoring system and correlative analysis of the strength and effectiveness of nationwide high school cardiopulmonary resuscitation mandates: Insights from a high school CPR study. Heart rhythm 2025. link 18 Kondo Y, Chiba T, Osawa M, Kawasaki Y, Goto T, Coles JA et al.. Medical Cost Analysis of Implantable Cardioverter Defibrillators for Primary Prevention Among Cardiac Arrest Patients. Circulation journal : official journal of the Japanese Circulation Society 2025. link 19 Barkauskas R, Jenewein T, Scheiper-Welling S, Wilmes V, Niess C, Petzel-Witt S et al.. From rare events to systematic data collection: the RESCUED registry for sudden cardiac death in the young in Germany. Clinical research in cardiology : official journal of the German Cardiac Society 2025. link 20 Caudal A, Liu Y, Pang PD, Maison DP, Nakasuka K, Feng J et al.. Transcriptomic Profiling of Human Myocardium at Sudden Death to Define Vulnerable Substrate for Lethal Arrhythmias. JACC. Clinical electrophysiology 2025. link 21 Vamos M, Zsigmond EJ, Biffi M, Gausz FD, Keller N, Kupo P et al.. Efficacy and safety of the subcutaneous implantable cardioverter-defibrillator in patients with and without obesity: A meta-analysis. Heart rhythm 2025. link 22 He S, Du M, Wang Z, Zang Y, Ning G, Pang S et al.. Artificial intelligence in electrocardiogram signals for sudden cardiac death prediction: a systematic review and meta-analysis. Systematic reviews 2025. link 23 Duncker D, Garcia R, Bonderman D, Casolo G, Farkowski M, Israel C et al.. A review on wearable cardioverter-defibrillators in clinical practice for sudden cardiac death prevention and heart failure management. Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 2025. link 24 Palsøe MK, Hansen CJ, Torp-Pedersen C, Winkel BG, Linnet K, Tfelt-Hansen J et al.. Proarrhythmic drugs, drug levels, and polypharmacy in victims of sudden arrhythmic death syndrome: An autopsy-based study from Denmark. Heart rhythm 2024. link 25 Zhang L, Liu B, Li S, Wang J, Mu Y, Zhou X et al.. Deep learning-based measurement of echocardiographic data and its application in the diagnosis of sudden cardiac death. Biotechnology & genetic engineering reviews 2024. link 26 Sottmann L, Schmeling A. Philemon and Baucis death: a literature review. International journal of legal medicine 2024. link 27 Zhang X, Xiao J, Yang F, Qu H, Ye C, Chen S et al.. Identification of sudden cardiac death from human blood using ATR-FTIR spectroscopy and machine learning. International journal of legal medicine 2024. link 28 Fahy L, Rowe S, Nehme Z, Stub D, Zentner D, James P et al.. Prevalence of atrial septal defects and patent foramen ovale in a cohort of sudden cardiac death patients undergoing autopsy. Journal of cardiology 2024. link 29 Hansen CJ, Svane J, Palsøe MK, Isbister JC, Paratz E, Molina P et al.. Toxicology Screening in Sports-Related Sudden Cardiac Death: A Multinational Observational Study. JACC. Clinical electrophysiology 2024. link 30 Van Goethem A, De Temmerman G, Van Hoyweghen A, Volders W, Bracke P, Jacobs W. Air bubble artifact: why postmortem brain MRI should always be combined with postmortem CT. Forensic science, medicine, and pathology 2024. link 31 Márquez-Murillo MF, Chávez-Gutiérrez CA, Díaz-Tostado S, Bustillos-García G, Gómez-Flores J, Nava-Townsend S. Use of subcutaneous cardioverter-defibrillator. First cases reported from National Institute of Cardiology Ignacio Chávez-Mexico. Archivos de cardiologia de Mexico 2023. link 32 Galambos C, Bush D, Abman SH, Caplan M. Prominent Intrapulmonary Shunt Vessels and Altered Lung Development in Infants With Sudden Unexplained Infant Death. The Journal of pediatrics 2023. link 33 Cornelissen A, Guo L, Neally SJ, Kleinberg L, Forster A, Nair R et al.. Relationships between neighborhood disadvantage and cardiovascular findings at autopsy in subjects with sudden death. American heart journal 2023. link 34 Petek BJ, Drezner JA, Churchill TW. The International Criteria for Electrocardiogram Interpretation in Athletes: Common Pitfalls and Future Directions. Cardiology clinics 2023. link 35 Ha FJ, Han HC, Sanders P, La Gerche A, Teh AW, Farouque O et al.. Sudden cardiac death related to physical exercise in the young: a nationwide cohort study of Australia. Internal medicine journal 2023. link 36 Cavarretta E, Pingitore A, Della Porta S, Capitani R, Bernardi M, Sciarra L et al.. Accuracy of the "International Criteria" for ECG screening in athletes in comparison with previous published criteria: rationale and design of a diagnostic meta-analysis. Minerva cardiology and angiology 2022. link 37 Servick K. Geneticists find clues to unexplained child deaths. Science (New York, N.Y.) 2022. link 38 D'Ascenzi F, Valentini F, Pistoresi S, Frascaro F, Piu P, Cavigli L et al.. Causes of sudden cardiac death in young athletes and non-athletes: systematic review and meta-analysis: Sudden cardiac death in the young. Trends in cardiovascular medicine 2022. link 39 Egger F, Scharhag J, Kästner A, Dvořák J, Bohm P, Meyer T. FIFA Sudden Death Registry (FIFA-SDR): a prospective, observational study of sudden death in worldwide football from 2014 to 2018. British journal of sports medicine 2022. link 40 Ishii T, Nawa N, Morio T, Fujiwara T. Association between nationwide introduction of public-access defibrillation and sudden cardiac death in Japan: An interrupted time-series analysis. International journal of cardiology 2022. link 41 Dalgaard CV, Hansen BL, Jacobsen EM, Kjerrumgaard A, Tfelt-Hansen J, Weeke PE et al.. Sudden unexplained death versus nonautopsied possible sudden cardiac death: Findings in relatives. Journal of cardiovascular electrophysiology 2022. link 42 Frontera A, Anselmino M, Matta M, Baccelli A, Vlachos K, Bonsignore A et al.. Ante-mortem characterization of sudden deaths as first-manifestation in Italy. Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing 2022. link 43 Warming PE, Ågesen FN, Lynge TH, Jabbari R, Smits RLA, van Valkengoed IGM et al.. Harmonization of the definition of sudden cardiac death in longitudinal cohorts of the European Sudden Cardiac Arrest network - towards Prevention, Education, and New Effective Treatments (ESCAPE-NET) consortium. American heart journal 2022. link 44 Fan L, Yin P, Xu Z. The genetic basis of sudden death in young people - Cardiac and non-cardiac. Gene 2022. link 45 Williams AF, Bryan AF, Tomasek K, Fulmer CA, Gregory K, Bozeman C et al.. Developmental changes in cardiac expression of KCNQ1 and SCN5A spliceoforms: Implications for sudden unexpected infant death. Heart rhythm 2022. link 46 Moey MYY, Wilkin M, Gandjbakhch E, Bachelot A, Abbar B, Pinna B et al.. Androgens, QT, sex and ventricular repolarization-a double-edged sword: A case series. Therapie 2022. link 47 Albiński M, Saubade M, Menafoglio A, Meyer P, Capelli B, Perrin T et al.. Diagnostic yield and cost analysis of electrocardiographic screening in Swiss paediatric athletes. Journal of science and medicine in sport 2022. link 48 Philippon F, Domain G, Sarrazin JF, Nault I, O'Hara G, Champagne J et al.. Evolution of Devices to Prevent Sudden Cardiac Death: Contemporary Clinical Impacts. The Canadian journal of cardiology 2022. link 49 Palmieri F, Gomis P, Ferreira D, Pueyo E, Martinez JP, Laguna P et al.. Weighted Time Warping Improves T-Wave Morphology Markers Clinical Significance. IEEE transactions on bio-medical engineering 2022. link 50 Duffy M, Garland J, Ondruschka B, Paton JFR, Bardsley EN, Wong CX et al.. Stellate ganglionitis in sudden cardiac death: A case report. Autonomic neuroscience : basic & clinical 2021. link 51 Neuharth-Pritchett S, Salm Ward T, McLaughlin KC, Jackson VM. A comparison of safe sleep violations in child care and family child care learning homes in Georgia. Child: care, health and development 2021. link 52 Goldenberg I, Erath JW, Russo AM, Burch AE, Assmus B, Bonderman D et al.. Sex differences in arrhythmic burden with the wearable cardioverter-defibrillator. Heart rhythm 2021. link 53 Jaouadi H, Bouyacoub Y, Chabrak S, Kraoua L, Zaroui A, Elouej S et al.. Multiallelic rare variants support an oligogenic origin of sudden cardiac death in the young. Herz 2021. link 54 Ripoll-Vera T, Pérez Luengo C, Borondo Alcázar JC, García Ruiz AB, Sánchez Del Valle N, Barceló Martín B et al.. Sudden cardiac death in persons aged 50 years or younger: diagnostic yield of a regional molecular autopsy program using massive sequencing. Revista espanola de cardiologia (English ed.) 2021. link 55 Cheung CC, Olgin JE, Lee BK. Wearable cardioverter-defibrillators: A review of evidence and indications. Trends in cardiovascular medicine 2021. link 56 Banner J, Basso C, Tolkien Z, Kholova I, Michaud K, Gallagher PJ. Autopsy examination in sudden cardiac death: a current perspective on behalf of the Association for European Cardiovascular Pathology. Virchows Archiv : an international journal of pathology 2021. link 57 Zhao A, Shen J, Ding Y, Sheng M, Zuo M, Lv H et al.. Long-read sequencing identified a novel nonsense and a de novo missense of PPA2 in trans in a Chinese patient with autosomal recessive infantile sudden cardiac failure. Clinica chimica acta; international journal of clinical chemistry 2021. link 58 Blix AS. A possible cause of Sudden Infant Death Syndrome. Medical hypotheses 2020. link 59 Sontag JM, Singh B, Ostfeld BM, Hegyi T, Steinberg MB, Delnevo CD. Obstetricians' and Gynecologists' Communication Practices around Smoking Cessation in Pregnancy, Secondhand Smoke and Sudden Infant Death Syndrome (SIDS): A Survey. International journal of environmental research and public health 2020. link 60 Sassone B, Mandini S, Grazzi G, Mazzoni G, Myers J, Pasanisi G. Impact of COVID-19 Pandemic on Physical Activity in Patients With Implantable Cardioverter-Defibrillators. Journal of cardiopulmonary rehabilitation and prevention 2020. link 61 Willy K, Reinke F, Bögeholz N, Köbe J, Eckardt L, Frommeyer G. Performance of the entirely subcutaneous ICD in borderline indications. Clinical research in cardiology : official journal of the German Cardiac Society 2020. link 62 Holkeri A, Eranti A, Haukilahti MAE, Kerola T, Kenttä TV, Tikkanen JT et al.. Impact of age and sex on the long-term prognosis associated with early repolarization in the general population. Heart rhythm 2020. link 63 Thomas KL, Sullivan LT, Al-Khatib SM, LaPointe NA, Sears S, Kosinski AS et al.. Videos to reduce racial disparities in ICD therapy Via Innovative Designs (VIVID) trial: Rational, design and methodology. American heart journal 2020. link 64 Cao Z, Zhao M, Xu C, Zhang T, Jia Y, Wang T et al.. Evaluation of Agonal Cardiac Function for Sudden Cardiac Death in Forensic Medicine with Postmortem Brain Natriuretic Peptide (BNP) and NT-proBNP: A Meta-analysis. Journal of forensic sciences 2020. link 65 Holkeri A, Eranti A, Haukilahti MAE, Kerola T, Kenttä TV, Tikkanen JT et al.. Predicting sudden cardiac death in a general population using an electrocardiographic risk score. Heart (British Cardiac Society) 2020. link 66 Szymanski LJ, Ernst LM. Cartilaginous Metaplasia Involving the Atrioventricular Node and Bundle of His Contributing to Sudden Early Neonatal Death. Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society 2020. link 67 Li X, Zhao S, Chen K, Hua W, Su Y, Yang J et al.. Dose-response association of implantable device-measured physical activity with long-term cardiac death and all-cause mortality in patients at high risk of sudden cardiac death: a cohort study. The international journal of behavioral nutrition and physical activity 2020. link 68 Sterliński M, Oręziak A, Przybylski A, Średniawa B. Experts of the Heart Rhythm Section of the Polish Cardiac Society: opinion on the use of wearable cardioverter-defibrillators in Poland. Kardiologia polska 2019. link 69 Campi R, Bonati M. Can we still do something-and what?-for a seemingly missing syndrome?. Italian journal of pediatrics 2019. link 70 Paterick ZR, Paterick TE. Preparticipation Cardiovascular Screening of Student-Athletes with Echocardiography: Ethical, Clinical, Economic, and Legal Considerations. Current cardiology reports 2019. link 71 Kaya E, Jánosi RA, Azizy O, Wakili R, Rassaf T. Conscious sedation during subcutaneous implantable cardioverter-defibrillator implantation using the intermuscular technique. Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing 2019. link 72 Mongkhonsiri P, Tong-Un T, Wyss JM, Roysommuti S. Blunted Nighttime Sympathetic Nervous System Response to Stress Among Thai Men with Positive Family History of Sudden Unexplained Nocturnal Death Syndrome. International heart journal 2019. link 73 Bates K, Sweeting J, Yeates L, McDonald K, Semsarian C, Ingles J. Psychological adaptation to molecular autopsy findings following sudden cardiac death in the young. Genetics in medicine : official journal of the American College of Medical Genetics 2019. link 74 Srettabunjong S. Sudden Unexplained Nocturnal Death Syndrome: Epidemiological and Morphological Characteristics in Thai Autopsy Cases. Journal of forensic sciences 2019. link 75 Reinier K, Rusinaru C, Chugh SS. Race, ethnicity, and the risk of sudden death<sup/>. Trends in cardiovascular medicine 2019. link 76 Tang Y, Williams N, Sampson BA. Genetic testing in sudden unexpected natural death in the young: New York City Office of Chief Medical Examiner's experience and perspective. Forensic science, medicine, and pathology 2019. link 77 Ebrahimzadeh E, Foroutan A, Shams M, Baradaran R, Rajabion L, Joulani M et al.. An optimal strategy for prediction of sudden cardiac death through a pioneering feature-selection approach from HRV signal. Computer methods and programs in biomedicine 2019. link 78 Haïssaguerre M, Nademanee K, Hocini M, Cheniti G, Duchateau J, Frontera A et al.. Depolarization versus repolarization abnormality underlying inferolateral J-wave syndromes: New concepts in sudden cardiac death with apparently normal hearts. Heart rhythm 2019. link 79 Michaels NL, Anderson SE, McKenzie LB, Katz ML. Infant Safe Sleep: A Survey of the Knowledge, Attitudes, and Behaviors of Obstetric Physicians. Journal of community health 2018. link 80 Dvir H, Elbaz I, Havlin S, Appelbaum L, Ivanov PC, Bartsch RP. Neuronal noise as an origin of sleep arousals and its role in sudden infant death syndrome. Science advances 2018. link 81 Adams WM, Scarneo SE, Casa DJ. Assessment of Evidence-Based Health and Safety Policies on Sudden Death and Concussion Management in Secondary School Athletics: A Benchmark Study. Journal of athletic training 2018. link 82 Miars CW, Stamatis A, Morgan GB, Drezner JA. Cardiovascular Screening Practices and Attitudes From the NCAA Autonomous "Power" 5 Conferences. Sports health 2018. link 83 Dave S, Feinstein R. Cardiovascular Clearance for Sports Participation. Current problems in pediatric and adolescent health care 2018. link 84 Bjune T, Risgaard B, Kruckow L, Glinge C, Ingemann-Hansen O, Leth PM et al.. Post-mortem toxicology in young sudden cardiac death victims: a nationwide cohort study. Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 2018. link 85 Lin Y, He S, Liao Z, Feng R, Liu R, Peng Y et al.. Whole exome sequencing identified a pathogenic mutation in RYR2 in a Chinese family with unexplained sudden death. Journal of electrocardiology 2018. link 86 Jenewein T, Neumann T, Erkapic D, Kuniss M, Verhoff MA, Thiel G et al.. Influence of genetic modifiers on sudden cardiac death cases. International journal of legal medicine 2018. link 87 Viani S, Soldati E, DI Cori A, Segreti L, Paperini L, DE Lucia R et al.. Prevention of sudden cardiac death: from wearable to subcutaneous cardioverter defibrillator. Minerva cardioangiologica 2018. link 88 Bogle BM, Ning H, Goldberger JJ, Mehrotra S, Lloyd-Jones DM. A Simple Community-Based Risk-Prediction Score for Sudden Cardiac Death. The American journal of medicine 2018. link 89 Aquila I, Gratteri S, Sacco MA, Fineschi V, Magi S, Castaldo P et al.. The Biological Effects of Kambo: Is There a Relationship Between its Administration and Sudden Death?. Journal of forensic sciences 2018. link 90 Vora A, Burkule N, Contractor A, Bhargava K. Prevention of sudden cardiac death in athletes, sportspersons and marathoners in India. Indian heart journal 2018. link 91 Hagnäs MJ, Lakka TA, Mäkikallio TH, Kurl S, Savonen K, Rauramaa R et al.. High Leisure-Time Physical Activity Is Associated With Reduced Risk of Sudden Cardiac Death Among Men With Low Cardiorespiratory Fitness. The Canadian journal of cardiology 2018. link 92 Ye Y, Larrat EP, Caffrey AR. Algorithms used to identify ventricular arrhythmias and sudden cardiac death in retrospective studies: a systematic literature review. Therapeutic advances in cardiovascular disease 2018. link 93 Ebrahimzadeh E, Manuchehri MS, Amoozegar S, Araabi BN, Soltanian-Zadeh H. A time local subset feature selection for prediction of sudden cardiac death from ECG signal. Medical & biological engineering & computing 2018. link 94 Agarwal M, Narcisse D, Khouzam N, Khouzam RN. Wearable Cardioverter Defibrillator "The Lifevest": Device Design, Limitations, and Areas of Improvement. Current problems in cardiology 2018. link 95 Hudzik B, Hudzik M, Lekston A, Gasior M. Sudden unexplained cardiac deaths in young adults: a call for multidisciplinary approach. Acta cardiologica 2018. link 96 Wu J, Wu Q, Dai W, Kong J, Lv J, Yu X et al.. Serum lipid feature and potential biomarkers of lethal ventricular tachyarrhythmia (LVTA) induced by myocardial ion channel diseases: a rat model study. International journal of legal medicine 2018. link 97 Kentaro S, Kimiharu I, Sari M, Shojiro T, Yuko K. Exploration of Predictive Biomarkers for Sudden Unexplained Cardiac Death in Nonelderly People: A Case-Control Study With Biochemical Parameters Related to Heart Failure. The American journal of forensic medicine and pathology 2018. link 98 Bennett M, Parkash R, Nery P, Sénéchal M, Mondesert B, Birnie D et al.. Canadian Cardiovascular Society/Canadian Heart Rhythm Society 2016 Implantable Cardioverter-Defibrillator Guidelines. The Canadian journal of cardiology 2017. link 99 Christensen ED, Berger J, Alashari MM, Coon H, Robison C, Ho HT et al.. Sudden infant death "syndrome"-Insights and future directions from a Utah population database analysis. American journal of medical genetics. Part A 2017. link 100 Lucas C, Kerkhof DL, Briggs JE, Corrado GD. The Use of Echocardiograms in Preparticipation Examinations. Current sports medicine reports 2017. link