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Cardiology27 papers

Atrial septal aneurysm

Last edited: 4/22/2026

Overview

Atrial septal aneurysm (ASA) is a localized bulging of the interatrial septum, often characterized by a base diameter ≥ 15 mm and excursion ≥ 10 mm, potentially leading to complications such as arrhythmias, right-to-left shunts, and systemic embolism 134.

Diagnosis

  • Echocardiography: Essential for diagnosis, typically using transthoracic echocardiography with tissue Doppler imaging to assess atrial electromechanical delay (AEMD) 14.
  • Criteria: Minimal aneurysmal base ≥ 15 mm and excursion ≥ 10 mm 1.
  • Views: Best visualized in subcostal four-chamber and parasternal short-axis views 4.
  • Additional Techniques: Ultrasound contrast can confirm the diagnosis 5.
  • Management

  • Anticoagulation: Recommended for patients with a history of systemic embolism to prevent recurrent events 34.
  • Monitoring: Regular echocardiographic follow-up to assess aneurysm size and function 5.
  • Surgical Intervention: Considered in cases causing significant obstruction or refractory symptoms 2.
  • Special Populations

  • Comorbidities: Patients with mitral valve prolapse or atrial septal defects may require specific management considerations 4.
  • Symptomatic vs Asymptomatic: Asymptomatic patients may only need surveillance, while symptomatic patients may require more aggressive intervention 5.
  • Key Recommendations

  • Echocardiographic Monitoring: Regular echocardiographic evaluation to assess AEMD and aneurysm dynamics is crucial for early detection of complications (Evidence: Moderate 14).
  • Anticoagulation Therapy: Initiate anticoagulation in patients with a history of systemic embolism due to ASA to reduce recurrence risk (Evidence: Moderate 34).
  • Surgical Evaluation: Consider surgical intervention for symptomatic patients or those with significant right atrial obstruction (Evidence: Weak 2).
  • References

    1 Okutucu S, Evranos B, Aytemir K, Kaya EB, Deveci OS, Deniz A et al.. Relationship between atrial septal aneurysms and atrial electromechanical delay. The international journal of cardiovascular imaging 2011. link 2 Angelini P, Wilansky S, Gaos C, Montazavi A, Boncompagni E, Cooley DA. Prolapsing large aneurysm of the atrial septum simulating a right atrial mass. Catheterization and cardiovascular diagnosis 1992. link 3 Shenoy MM, Vijaykumar PM, Friedman SA, Greif E. Atrial septal aneurysm associated with systemic embolism and interatrial right-to-left shunt. Archives of internal medicine 1987. link 4 Gallet B, Malergue MC, Adams C, Saudemont JP, Collot AM, Druon MC et al.. Atrial septal aneurysm--a potential cause of systemic embolism. An echocardiographic study. British heart journal 1985. link 5 Wysham DG, McPherson DD, Kerber RE. Asymptomatic aneurysm of the interatrial septum. Journal of the American College of Cardiology 1984. link80155-2)

    Original source

    1. [1]
      Relationship between atrial septal aneurysms and atrial electromechanical delay.Okutucu S, Evranos B, Aytemir K, Kaya EB, Deveci OS, Deniz A et al. The international journal of cardiovascular imaging (2011)
    2. [2]
      Prolapsing large aneurysm of the atrial septum simulating a right atrial mass.Angelini P, Wilansky S, Gaos C, Montazavi A, Boncompagni E, Cooley DA Catheterization and cardiovascular diagnosis (1992)
    3. [3]
      Atrial septal aneurysm associated with systemic embolism and interatrial right-to-left shunt.Shenoy MM, Vijaykumar PM, Friedman SA, Greif E Archives of internal medicine (1987)
    4. [4]
      Atrial septal aneurysm--a potential cause of systemic embolism. An echocardiographic study.Gallet B, Malergue MC, Adams C, Saudemont JP, Collot AM, Druon MC et al. British heart journal (1985)
    5. [5]
      Asymptomatic aneurysm of the interatrial septum.Wysham DG, McPherson DD, Kerber RE Journal of the American College of Cardiology (1984)

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