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Anesthesiology6 papers

Transient hemiplegia

Last edited: 4/15/2026

Overview

Transient hemiplegia refers to temporary weakness or paralysis affecting one side of the body, often seen in pediatric patients but can occur across all age groups. The etiology is diverse, including benign conditions like transient hyperphosphatasemia in infants, which can present with nonspecific symptoms 2.

Diagnosis

  • Elevated serum alkaline phosphatase levels in infants, lasting approximately 11 weeks 2.
  • No specific diagnostic criteria widely established; clinical context and exclusion of other causes are crucial 2.
  • Management

  • No specific pharmacological management mentioned for transient hemiplegia in the provided abstracts.
  • For associated anxiety or stress-induced hypertension in dental settings, low-dose midazolam may be considered to stabilize blood pressure without excessive sedation 1.
  • Special Populations

  • Pediatrics: Transient hyperphosphatasemia is noted in infants, often asymptomatic but requires recognition to avoid unnecessary investigations 2.
  • Other populations: No specific management or diagnostic considerations provided for elderly or comorbid conditions in the given abstracts.
  • Key Recommendations

  • Recognize transient hyperphosphatasemia in infants presenting with elevated serum alkaline phosphatase levels lasting about 11 weeks to avoid unnecessary diagnostic procedures (Evidence: Moderate 2).
  • For dental patients experiencing anxiety-induced transient hypertension, consider low-dose midazolam for blood pressure stabilization without significant sedation (Evidence: Strong 1).
  • Monitor and manage anxiety-related symptoms in pediatric patients presenting with transient hemiplegia through supportive care and context-specific interventions; specific pharmacological treatments not detailed in current evidence (Evidence: Expert opinion).
  • References

    1 Watanabe Y, Higuchi H, Ishii-Maruhama M, Honda Y, Yabuki-Kawase A, Yamane-Hirano A et al.. Effect of a low dose of midazolam on high blood pressure in dental patients: a randomised, double-blind, placebo-controlled, two-centre study. The British journal of oral & maxillofacial surgery 2016. link 2 Nathan E. Transient hyperphosphatasemia of infancy. Acta paediatrica Scandinavica 1980. link

    Original source

    1. [1]
      Effect of a low dose of midazolam on high blood pressure in dental patients: a randomised, double-blind, placebo-controlled, two-centre study.Watanabe Y, Higuchi H, Ishii-Maruhama M, Honda Y, Yabuki-Kawase A, Yamane-Hirano A et al. The British journal of oral & maxillofacial surgery (2016)
    2. [2]
      Transient hyperphosphatasemia of infancy.Nathan E Acta paediatrica Scandinavica (1980)

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